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Fluid makes up what percentage of our body
45-75%, this is affected by age and tissue ratio (adipose to skeletal ratio)
Rank the ages that have the most to the least amount of body make up from fluid
infants>young>elderly
What percent of skeletal muscles is water
75%
Filtrate vs urine
Filtrate: urine which is able to be modified
Urine: cannot be modified anywhere
Do we lose muscle mass when get older?
yes
What percentage of water is adipose tissue
20%
Why is having alot of adipose tissue bad
makes you more susceptible to fluid imbalance
What percent of fluid is found intracellulary
around 60-65% (majority of fluids in the body found intracellularly)
How is extracellular fluid split
Majority and can vary: interstitial fluid (32%) and blood plasma (8%)
Minority and is static: synovial fluid, eye fluid, CSF, inner ear, and serous fluid
How is interstitial fluid formed
by blood plasma
what is plasma
medium of blood which transports: gases, waste products and
When we eat something salty, water comes from what to balance the salt levels
interstitial fluid.
What are the main electrolytes we look at
Na+, Cl-, Mg+2
What is osmosis
the movement of water (it follows ions) through a selectively permeable membrane
Wha pressure does osmosis create
osmotic pressure
What is osmotic pressure
Pressure exerted on hypertonic side of membrane to prevent movement of water from hypotonic side
How does the kidney help with osmoregulation
reclaim ions or get rid of them
What is osmoles
number of particles/L of solution
How much Osmoles are produces when 1mol NaCl is dissolved
1 mol of Na+ and 1 mol of Cl- so two osmoles
If we regulate particle number (osmoes) we must also regulate
water
To control water level what do we move
anything dissolved in water
What is a major macromolecule which is metabolized and what is the waste product
protein and nitrogenous wastes
What molecules/products are seen in the byproduct of metabolism
H2O, CO2, and nitrogenous waste
What are the major processes the kidney is involved in
pH regulation: metabolic regulation
RBC production: Erythropoietin
Blood pressure regulation: Reinin-aldosterone-angiotensin pathway
What are the nitrogenous wastes
Ammonia, Urea, and Uric acid
Main way nitrogenous waste is excreted
The kidney
Why is the kidney involved in the blood cell production
it’s a major user of oxygen
What nitrogenous waste needs the most energy to be produced
1) Uric Acid
2) Urea
3) Ammonia
The more energy a nitrogenous waste is needed produced the___ is needed to excrete
less water
How do we get rid of ammonia
it enters the liver to be apart of the urea cycle (MAMMALS)
What is the use of Urea
it actually helps establish an osmotic gradient in the interstitial fluid and maintain cell volume
What is so dangerous about uric acid
it precipitate in water to form crystals which can cause gout
(due to, to much uric acid and typically seen around joints)
What animals produce uric acid
animals found in the desert and birds
(due to low levels of water)
What animal makes ammonium
basically every animal, as long as you have access to water you can make ammonia
(aquatic or terrestrial dwellers)
How is creatinine produced
from creatine metabolism in muscle, the metabolism uses a nonprotein source
What is creatinine
waste product and it’s only secreted
What is the characteristic of ammonia’s toxicity
highly toxic it can disrupt pH and chemical reaction
Who can produce urea
aquatic and terrestrial animals, all animals that have access to water
What is the characteristic of urea’s toxicity
less toxic than ammonia it can interfere with chemical reactions, it’s still toxic to cells must animals have evolved to get around the toxicity
What animal habitat produces a lot of uric acid
habitats with limited/no access to water: terrestrial dwellers and shelled embryos
What is the characteristic of Uric Acid toxicity
least toxic, but it’s secreted as semisolid paste or dense pallets
What animals are seen to secrete uric acid
reptiles, birds, insects, some species of arboreal frogs, and cockroaches
What do cockroaches do with uric acid
recycle nitrogen source when on a low protein diet to retain water
What is osmoconformer
They are isotonic with the environment, (REDO)
What animals are osmoconformer
mainly invertebrates (star fishes, crabs, jelly fishes, lobsters)
sharks, skates and hagfish
Osmoregulators
maintains H2O and ionic composition independent of the environment, (REDO)
What animals are typically osmoregulator
vertebrates
marine invertebrates living in costal lagoons and estuaries.
What are two ways animals with no multicellular excretory structure regulate osmotic pressure
via organelles like contractile vacuoles
via specialized glands like renette glands
How are protists omsmogregulators
They have contractile vacuole to regulate water content, to result in regulation of osmotic pressure
How do nematodes go through ostomicregulation
they have a renette glands
How does renette gland work
they take up fluid, MAY get some ion regulation, it is not organized into the kidney and could be stand alone or connected by tubules.
the fluid goes to the body surface and leaves (ions may leave with fluid)
Where have seen something like the renette gland before
the antennal gland in crustascens (crayfish)
nephridia meaning
relating to kidney like structure
What type of animals have nephridial organs
invertebrates
What does nephridial organ do
seen in osmoregulation and excretion
What is the structure of nephridial organ
they are simple or branching tubules which is connected to the nephridiopores
What is nephridiopores
a surface opening found in invertebrates
Two types of nephridial organs found in invertebrates
protonpehridia and metanephridia
What animals have protonephria
acoelamtes and coelomates, platyhelminths and some annelids
(INSECTS)
If we want fluid to keep leaving a pore we need…
a current (seen in protonephrida, metanephridia and us)
What are the structures/characteristics involved with protonephridida
tubules, flame cells, excess fluid, hypoostmoic urine
closed internally by flame cells
What is the tubule structure characteristic of protonephridia
they have interstitial flame cells on the end of tubules and internal cilia which propel intersistial fluid into tubules
What do the flame cells in protonephrida do
they create a current, because they have cilia which beat to draw water in tubule
What is the placement of flamecell
hanging into the lumen, it has slit like openings with cilia that hangs down
What does the slits in the flame cells do
they act as hole to move interstitial fluid into excretory duct
In protonephridia is the fluid inside the tubule filtrate or urine
filtrate
In protonehphrdia how does urine leave
through the nephridapore
What is the composition of protonephrdia urine/waste
it is hypoostmic and most of their nitrogenous waste leaves across body surface
What kind of animals have a metanephridida
most annelids, mollusks and crustaceans, and coelomates
How is the tubule structure of metaphridida
it is open to the inside and outside end of the nephrdidapore
How is the current created in metanephridida
they have a funnel cell structure
What is the characteristics of funnel cell structure
open into intersititum and found on end of tubules they have cilia that extends out from the internal opening
What does the cilia do in the funnel cells structure of metanephridia
they beat to draw fluid into tubule
What is around the tubule of metanephridia
circulatory system which is able to add or take out things from the filtrate
What happens with when there is excess fluid in metanephrida
it still goes into the tubules but solutes from the coelem goes into the nephridpore
What does circulatory system around tubules in metanephridia allow for
for urine to be hypotonic, isotonic, and hypertonic
What is odd about metanephridida
there is intake of fluid one segment and modification in another segment
Insects have what kind of tubules
Malpighian tubules
Where is the malpighian tubules located in sects
intersititum and it extends from the gut wall and it closed to the interstitium
There is no cilia in malpighian tubules so how do we create a current
by moving ions into tubules so that water follows
How does the mapighian tubules work
ions (K-, Cl-) and uric acid is transported into lumen (via a pump) the lumen is now hypertonic so water follows, fluid is then modified (to a pallet due to pH) and passes along tubules, which it empties into gut where cells in the rectum can modify it
What kind of circulation does the mapighian tubules and gut have
counter current
What does impact on counter current flow of malpighian tubules and gut
water can be taken up from the gut
What kind of urine can malpighian tubules produce
all 3 types, hypotonic, isotonic, and hypertonic
All vertebrates have what type of osmoregulation and excretion
the same as us
In vertebrates what does the kidney do
main osmoregulatory and excretion organ,
we do have other structures which can excrete waste product it’s not the major one
How does kidney produce waste product
producing urine
How does digestive system get rid of waste product
through feces
How doe skin get rid of waste product
sweat
How do lungs get rid of waste products
exhaling air which contains water vapor and carbon dioxide
What is within the sweat that we excrete
water, ammonia, urea, and salt
A freshwater fish is what to their enviorment
hypertonic
The largest exposed surface to water of a fish
the gills
What does gills do in fish
we gain alot of water via osmosis but the gills help us with ion regulation
What does kidney of freshwater fish produce
large volume of dilute urine which is 10% nitrogenous waste
How does water move in freshwater fish
it moves inside of them but they are not drinking it, this cause a very dilute urine, and urine is hypertonic to the cell
(any water needed is taken up by the gills)
In saltwater fish what is the fish to the enviorment
hypotonic
Since we lose water to the environment what is the kidney production level
produce very little amounts of urine which is isotonic and it has small or no glomeruli