Antidepressants

Nortriptylin

TCA

Amitriptyline

TCA; Also indicated for migraines and chronic pain. Turns urine green.

Doxepin

TCA; Also used as a hypnotic and anti-pruritic due to it’s histamine blocking effects.

Impiramine

TCA; Also indicated for bed-wetting in children (causes contraction of the external urinary sphincter).

Trimipramine

TCA

Reserpine

A drug used in the treatment of HTN and schizophrenia can cause depression because it depletes the vesicular storage of amine neurotransmitters

Phenelzine

Classic MAOI; Irreversible and non-selective; Cause sexual dysfunction; More sedative than other MAOIs. Hepatotoxicity is likely.

Tanylcypromine

Classic MAOI; Irreversible and non-selective; Cause sexual dysfunction.

Isocarboxazid

Classic MAOI; Irreversible and non-selective. Hepatotoxicity is likely.

Moclobemide

Reversible inhibitor of MAO-A (RIMA).

Deprenyl

AKA Selegeline is a selective MAO-B inhibitor and a non-selective MAO inhibitor in high doses. It is used for the treatment of neurodegenerative diseases in lower doses.

Fluoxetine

SSRI; The active metabolite of this drug has a 7-9-day half-life. Also used to treat OCD and Bulimia nervosa; Usually prescribed after breakfast because of it’s effects on sleep. Inhibits CYP450.

Citalopram

SSRI

Sertraline

SSRI; Also used to treat PTSD

Fluvoxamine

SSRI; Also used to treat OCD and GAD. Inhibits CYP450.

Paroxetine

SSRI; Also used to treat PTSD. Inhibits CYP450.

Clomipramine

TCA; Also used to treat OCD

Venlafaxine

SNRI; Weak inhibitor of NET. Also used to treat GAD.

Doluxetine

SNRI;

Desvenlafaxine

SNRI

Milnacipran

SNRI

L-milnacipran

SNRI

Amoxapine

SNRI; Not tricyclic.

Mirtazapine

SNRI; Presynaptic alpha2 inhibitor. Potent H1 antagonist.

Maprotiline

SNRI; Not tricyclic.

Trazodone

SARI; 5-HT2A modulator.

Nefazodone

SARI; 5-HT2A modulator.

Bupropion

NDRI; Causes presynaptic release of catecholamines (amphetamine). No sexual dysfunction. Used in smoking cessation. Used along Naltrexone for weight-loss.