Antidepressants II: SSRIs, SNRIs & Alternative Treatments

Flashcards covering key concepts related to SSRIs, SNRIs, and alternative treatments for depression based on recent lecture notes.

The first SSRI used as a first-line antidepressant was __.

Fluoxetine (Prozac)

Which SSRI is known to have a half-life of about 22 hours and is more potent than Fluoxetine in 5-HT reuptake inhibition? __.

Sertraline (Zoloft)

Venlafaxine is an example of a __ which also has low to moderate NE reuptake inhibition.

Serotonin-norepinephrine reuptake inhibitor (SNRI)

The 'F.I.N.I.S.H.' symptoms are associated with __.

Antidepressant Discontinuation Syndrome

Duloxetine (Cymbalta) is often used to treat both depression and __.

Anxiety

The pharmaceutical compound __ is fast-tracked as a breakthrough therapy for treatment-resistant MDD.

Ketamine

St. John's wort is noted for its reduction in __ scores in meta-analysis of RCTs as monotherapy.

Ham-D

The group of antidepressants that includes Trazodone and Bupropion are considered to be __ medications.

Antidepressants

The therapeutic effect of SSRIs is mainly due to the reuptake inhibition of __.

5-HT (serotonin)

The most prescribed antidepressant in recent years has been __.

Sertraline (Zoloft)