Top 200 Medications of 2025 - RxTechExam.com

Ethinyl Estradiol/Norgestimate

Brand: Ortho Tri-Cyclen

Class: Oral Contraceptive

Contraindication: Pregnancy Category X

Indication: Pregnancy Prevention, Hormone Regulation

Schedule: NCLM

Ethinyl Estradiol/Drosperinone

Brand: Yaz, Yazmin, Gianvi, Nikki

Class: Oral Contraceptive

Contraindication: Pregnancy Category X

Indication: Pregnancy Prevention, Hormone Regulation

Schedule: NCLM

Semaglutide

Brand: Ozempic

Class: GLP-1 agonists

Indication: Type 2 Diabetes (off-label weight loss)

Schedule: NCLM

Metoprolol tartrate

Brand: Lopressor

Class: Beta-blocker

Indication: Antihypertensive

Schedule: NCLM

Clopidogrel

Brand: Plavix

Class: P2Y12 Inhibitor, Anti-platelet

Drug Interaction: PPIs can reduce effectiveness

Indication: Clot Prevention

Schedule: NCLM

Venlafaxine

Brand: Effexor

Class: SNRI

Interaction: Serotonin Syndrome with MAOIs

Indication: Antidepressant

Schedule: NCLM

Clonazepam

Brand: Klonopin

Class: Benzodiazepine

Drug Interaction: Opioids can cause respiratory depression

Contraindication: Pregnancy Category D

Indication: Anxiety, Sedative

Schedule: IV

Allopurinol

Brand: Zyloprim

Class: Xanthine Oxidase Inhibitor

Indication: Gout Treatment

Schedule: NCLM

Methylphenidate

Brand: Ritalin, Concerta

Class: Stimulant

Indication: ADHD

Schedule: II

Donepezil

Brand: Aricept

Class: Cholinesterase Inhibitor

Indication: Alzheimer's

Schedule: NCLM

Losartan/Hydrochlorothiazide

Brand: Hyzaar

Class: ARB/Thiazide Diuretic

Drug Interaction: Can increase Digoxin activity

Indication: Antihypertensive

Schedule: NCLM

Hydroxyzine

Brand: Atarax, Vistaril

Class: H1RA, Anti-Histamine

Indication: Allergies

Schedule: NCLM

Prednisolone

Brand: OraPred

Class: Corticosteroid

Indication: Anti-inflammatory

Schedule: NCLM

Spironolactone

Brand: Aldactone

Class: Potassium-Sparing Diuretic

Drug Interaction: Can increase Digoxin activity

Indication: Antihypertensive

Schedule: NCLM

Oxybutynin

Brand: Ditropan

Class: Anticholinergic

Indication: Overactive Bladder

Schedule: NCLM

Thyroid Extract

Brand: Armour Thyroid

Class: Thyroid Hormone

Indication: Hypothyroidism

Schedule: NCLM

Fenofibrate

Brand: Tricor

Class: Fibric Acid Derivative

Indication: Cholesterol Lowering

Schedule: NCLM

Triamterene/HCTZ

Brand: Dyazide, Maxzide

Class: Potassium Sparing Diuretic/Thiazide Diuretic

Drug Interaction: Can increase Digoxin activity

Indication: Antihypertensive

Schedule: NCLM

Guanfacine

Brand: Tenex

Class: Alpha-2 Agonist

Indication: ADHD, Antihypertensive

Schedule: NCLM

Cephalexin

Brand: Keflex

Class: Cephalosporin Antibiotic

Drug Interactions:

1) reduce effectiveness of birth control

2) Increased risk of bleeding with anticoagulants

Indication: Bacterial Infection

Schedule: NCLM

Lisinopril

Brand: Prinivil

Class: ACEi

Contraindication: Pregnancy Category D

Indication: Antihypertensive

Schedule: NCLM

Atorvastatin

Brand: Lipitor

Class: HMG-CoA Reductase Inhibitor

Food Interaction: Grapefruit inhibits metabolism leading to muscle damage

Contraindication: Pregnancy Category X

Indication: Cholesterol lowering

Schedule: NCLM

Levothyroxine

Brand: Synthroid, Levoxyl

Class: Thyroid hormone

Indication: Hypothyroidism

Schedule: NCLM

Metformin

Brand: Glucophage

Class: Biguanide

Indication: Diabetes medication

Schedule: NCLM

Amlodipine

Brand: Norvasc

Class: Calcium Channel Blocker

Indication: Antihypertensive

Schedule: NCLM

Metoprolol succinate ER

Brand: Toprol XL

Class: Beta-blocker

Indication: Antihypertensive

Schedule: NCLM

Omeprazole

Brand: Prilosec

Class: PPI

Drug Interaction: Can reduce effectiveness of clopidogrel

Indication: Acid-Reflux/GERD

Schedule: OTC & NCLM (strength)

Simvastatin

Brand: Zocor

Class: HMG-CoA Reductase Inhibitor

Food Interaction: Grapefruit inhibits metabolism leading to muscle damage

Contraindication: Pregnancy Category X

Indication: Cholesterol lowering

Schedule: NCLM

Losartan potassium

Brand: Cozaar

Class: ARB

Indication: Antihypertensive

Schedule: NCLM

Albuterol

Brand: ProAir HFA, Ventolin HFA

Class: Beta agonist

Indication: Bronchodilator, asthma

Schedule: NCLM

Gabapentin

Brand: Neurontin

Class: Anticonvulsant

Indication: Neuropathic pain, seizures

Schedule: NCLM, V (some states)

Hydrochlorothiazide

Brand: Microzide

Class: Thiazide diuretic

Drug Interaction: Can increase Digoxin activity

Indication: Antihypertensives

Schedule: NCLM

Hydrocodone/APAP

Brand: Vicodin, Norco, Lortab

Class: Opioid analgesic combination

Drug Interaction: Benzodiazepines can cause respiratory depression

Indication: Pain reliever

Schedule: II

Sertraline

Brand: Zoloft

Class: SSRI

Interaction: Serotonin Syndrome with MAOIs

Indication: Antidepressant

Schedule: NCLM

Fluticasone

Brand: Flonase

Class: Nasal steroid

Indication: Allergic rhinitis

Schedule: OTC & NCLM as generic

Montelukast

Brand: Singulair

Class: Leukotriene modulator

Indication: Asthma treatment

Schedule: NCLM

Furosemide

Brand: Lasix

Class: Loop of Henle diuretic

Drug Interactions:

1) Can increase Digoxin activity

2) Increased risk of bleeding with Anticoagulants

Indication: Antihypertensive

Schedule: NCLM

Amoxicillin

Brand: Amoxil

Class: Penicillin Antibiotic

Drug Interactions:

1) reduce effectiveness of birth control

2) Increased risk of bleeding with anticoagulants

Indication: Bacterial Infection

Schedule: NCLM

Pantoprazole Sodium

Brand: Protonix

Class: PPI

Drug Interaction: Can reduce effectiveness of clopidogrel

Indication: Acid-Reflux/GERD

Schedule: NCLM

Acetaminophen

Brand: Tylenol

Class: Anti-pyretic, analgesic

Indication: Pain Relief

Schedule: NCLM

Citalopram

Brand: Celexa

Class: SSRI

Interaction: Serotonin Syndrome with MAOIs

Indication: Antidepressant

Schedule: NCLM

Mixed Amphetamine Salts

Brand: Adderall

Class: Stimulant

Indication: ADHD

Schedule: II

Ibuprofen

Brand: Motrin

Class: NSAID

Drug Interactions:

1) Can lead to higher Lithium Levels

2) Can lead to higher Methotrexate Levels

Interaction: Increased Risk of Bleeding with Coumadin

Contraindication: Pregnancy Category X

Indication: Pain/Inflammation Relief

Schedule: OTC & NCLM (strength)

Carvedilol

Brand: Coreg

Class: Beta-Blocker

Indication: Antihypertensives

Schedule: NCLM

Trazodone

Brand: Desyrel

Class: Antidepressant

Interaction: Serotonin Syndrome with MAOIs

Indication: Antidepressant, Sleep

Schedule: NCLM

Fluoxetine

Brand: Prozac

Class: SSRI

Indication: Antidepressant

Schedule: NCLM

Tramadol

Brand: Ultram

Class: Opioid Analgesic

Drug Interaction: Benzodiazepines can cause respiratory depression

Indication: Pain Relief

Schedule: IV

Rosuvastatin

Brand: Crestor

Class: HMG-CoA Reductase Inhibitor

Food Interaction: Grapefruit inhibits metabolism leading to muscle damage

Contraindication: Pregnancy Category X

Indication: Cholesterol Lowering

Schedule: NCLM

Insulin Glargine

Brand: Lantus

Class: Long-Acting Insulin

Indication: Diabetes Agent

Schedule: NCLM

REFRIGERATE

Propranolol

Brand: Inderal

Class: Beta-Blocker

Indication: Antihypertensive

Schedule: NCLM

Zolpidem Tartrate

Brand: Ambien

Class: Sedative

Indication: Sleep

Schedule: IV

Tamsulosin

Brand: Flomax

Class: Alpha-Blocker

Indication: Enlarged Prostate

Schedule: NCLM

Aspirin

Brand: Bayer

Class: NSAID, Anti-Platelet

Drug Interactions:

1) Can lead to higher Lithium Levels

2) Can lead to higher Methotrexate Levels

Interaction: Increased Risk of Bleeding with Coumadin

Indication: Pain relief, Clot Prevention

Schedule: OTC

Atenolol

Brand: Tenormin

Class: Beta-Blocker

Indication: Antihypertensive

Schedule: NCLM

Cyclobenzaprine

Brand: Flexeril

Class: Muscle Relaxer

Indication: Pain Relief

Schedule: NCLM

Oxycodone

Brand: OxyContin

Class: Opioid Analgesic

Drug Interaction: Benzodiazepines can cause respiratory depression

Indication: Pain Relief

Schedule: II

Potassium

Brand: Klor-Con

Class: Electrolyte

Indication: Electrolyte

Schedule: NCLM

Lisinopril/HCTZ

Brand: Zestoretic

Class: ACEi/Thiazide Diuretic

Drug Interaction: Can increase Digoxin activity

Contraindication: Pregnancy Category D

Indication: Antihypertensives

Schedule: NCLM

Ethinyl Estradiol/Norethindrone

Brand: Gildess, Junel, Loestrin, Microgestin

Class: Oral Contraceptive

Contraindication: Pregnancy Category X

Indication: Pregnancy Prevention, Hormone Regulation

Schedule: NCLM

Meloxicam

Brand: Mobic

Class: NSAID

Drug Interactions:

1) Can lead to higher Lithium Levels

2) Can lead to higher Methotrexate Levels

Interaction: Increased Risk of Bleeding with Coumadin

Indication: Pain/Inflammation Relief

Schedule: NCLM

Warfarin

Brand: Coumadin

Class: Vitamin K Antagonist

Drug Interactions: NSAIDs, Antibiotics, Fish Oil, Coenzyme 10, Garlic Supplements, Ginko Biloba, Vitamin K

Side Effects: Excessive bruising / bleeding

Contraindication: Pregnancy Category X

Indication: Anticoagulation, Blood Thinner

Schedule: NCLM

Glipizide

Brand: Glucotrol

Class: Sulfonylurea

Indication: Diabetes Agent

Schedule: NCLM

Azithromycin

Brand: Zithromax

Class: Macrolide Antibiotic

Drug Interactions:

1) reduce effectiveness of birth control

2) Increased risk of bleeding with anticoagulants

Indication: Bacterial Infection

Schedule: NCLM

Duloxetine

Brand: Cymbalta

Class: SNRI

Interaction: Serotonin Syndrome with MAOIs

Indication: Antidepressant

Schedule: NCLM

Ergocalciferol

Brand: Deltalin

Class: Vitamin D Supplement

Indication: Vitamin D Supplement

Schedule: NCLM

Metronidazole

Brand: Flagyl

Class: Antibiotic

Drug Interactions:

1) reduce effectiveness of birth control

2) Increased risk of bleeding with anticoagulants

Indication: Bacterial Infection

Schedule: NCLM

Insulin Aspart

Brand: Novolog

Class: Rapid Acting Insulin

Indication: Diabetes Agent

Schedule: NCLM

REFRIGERATE

Loratadine

Brand: Claritin

Class: H1RA, Anti-Histamine

Indication: Allergies

Schedule: NCLM

Lorazepam

Brand: Ativan

Class: Benzodiazepine

Drug Interaction: Opioids can cause respiratory depression

Contraindication: Pregnancy Category D

Indication: Anxiety, Sedative

Schedule: IV

Lamotrigine

Brand: Lamictal

Class: Anticonvulsant

Indication: Seizure Prevention

Schedule: NCLM

Estradiol

Brand: Estrace

Class: Female Hormone

Indication: Hormone Supplement

Schedule: NCLM

Glimepiride

Brand: Amaryl

Class: Sulfonylurea

Indication: Diabetes Agent

Schedule: NCLM

Fluticasone/Salmeterol

Brand: Advair Diskus

Class: Inhaled Corticosteroid/Long-Acting Beta-Agonist

Indication: Asthma Treatment

Schedule: NCLM

Folic Acid

Brand: Folate

Class: Vitamin Supplement

Indication: Vitamin Supplement

Schedule: NCLM

Cetirizine

Brand: Zyrtec

Class: H1RA, Anti-Histamine

Indication: Allergies

Schedule: OTC

Sumatriptan

Brand: Imitrex

Class: 5HT1 Agonist

Indication: Migraine treatment

Schedule: NCLM

Hydroxychloroquine

Brand: Plaquenil

Class: Anti-Malarial

Indication: Anti-Malaria, Rheumatoid Arthritis, Lupus

Schedule: NCLM

Ramipril

Brand: Altace

Class: ACEi

Contraindication: Pregnancy Category D

Indication: Antihypertensive

Schedule: NCLM

Paroxetine

Brand: Paxil

Class: SSRI

Interaction: Serotonin Syndrome with MAOIs

Indication: Antidepressant

Schedule: NCLM

Naproxen

Brand: Aleve

Class: NSAID

Drug Interactions:

1) Can lead to higher Lithium Levels

2) Can lead to higher Methotrexate Levels

Interaction: Increased Risk of Bleeding with Coumadin

Indication: Pain/Inflammation Relief

Schedule: OTC & NCLM (strength)

Testosterone

Brand: AndroGel

Class: Male Hormone Therapy

Indication: Hormone Therapy

Schedule: III

Pregabalin

Brand: Lyrica

Class: Anticonvulsant

Indication: Neuropathic Pain, Seizures

Schedule: V

Triamcinolone

Brand: Kenalog

Class: Corticosteroid

Indication: Anti-Inflammatory

Schedule: NCLM

Valsartan/HCTZ

Brand: Diovan HCT

Class: ARB/Thiazide Diuretic

Drug Interaction: Can increase Digoxin activity

Indication: Antihypertensive

Schedule: NCLM

Insulin Regular

Brand: Humulin R, Novolin R

Class: Short Acting Insulin

Indication: Diabetes Agent

Schedule: NCLM

REFRIGERATE

Benazepril

Brand: Lotensin

Class: ACEi

Contraindication: Pregnancy Category D

Indication: Antihypertensive

Schedule: NCLM

Diazepam

Brand: Valium

Class: Benzodiazepine

Drug Interaction: Opioids can cause respiratory depression

Contraindication: Pregnancy Category D

Indication: Sedative, Anti-Anxiety

Schedule: IV

Budesonide/Formoterol

Brand: Symbicort

Class: Inhaled Corticosteroid/Long-Acting Beta-Agonist

Indication: Asthma Treatment

Schedule: NCLM

Hydralazine

Brand: Apresoline

Class: Vasodilator

Indication: Angina, Heart Failure

Schedule: NCLM

Ethinyl Estradiol/Levonorgestrel

Brand: Amethia, Amethyst

Class: Oral Contraceptive

Contraindication: Pregnancy Category X

Indication: Pregnancy Prevention, Hormone Regulation

Schedule: NCLM

Diltiazem

Brand: Cardizem

Class: Calcium Channel Blocker

Indication: Antihypertensive

Schedule: NCLM

Celecoxib

Brand: Celebrex

Class: COX-2 Selective NSAID

Drug Interactions:

1) Can lead to higher Lithium Levels

2) Can lead to higher Methotrexate Levels

Interaction: Increased Risk of Bleeding with Coumadin

Indication: Pain/Inflammation Relief

Schedule: NCLM

Clindamycin

Brand: Cleocin

Class: Lincomycin Antibiotic

Drug Interactions:

1) reduce effectiveness of birth control

2) Increased risk of bleeding with anticoagulants

Indication: Bacterial Infection

Schedule: NCLM

Ciprofloxacin

Brand: Cipro

Class: Fluoroquinolone Antibiotic

Drug Interaction: Increased risk of bleeding with anticoagulants

Indication: Bacterial Infection

Schedule: NCLM

Gemfibrozil

Brand: Lopid

Class: Fibrate Derivative

Indication: Cholesterol Lowering

Schedule: NCLM

Topiramate

Brand: Topamax

Class: Anticonvulsant

Indication: Seizures, Migraines

Schedule: NCLM

Ropinirole

Brand: Requip

Class: Dopamine Agonist

Indication: Parkinson's Treatment

Schedule: NCLM

Metformin/Sitagliptin

Brand: Janumet

Class: Biguanide/DPP-4 Inhibitor

Indication: Diabetes Agent

Schedule: NCLM

Bacitracin/Neomycin/Polymyxin B

Brand: Neosporin

Class: Triple Antibiotic

Drug Interaction: Increased risk of bleeding with anticoagulants

Indication: Bacterial Infection

Schedule: OTC

Rivaroxaban

Brand: Xarelto

Class: Factor Xa Inhibitor

Drug Interactions:

1) Increased risk of bleeding with NSAIDs

2) Increased risk of bleeding with antibiotics

Interaction: Excessive bruising / bleeding

Indication: Anticoagulant, Blood Thinner

Schedule: NCLM