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119 Terms

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they need both if they are producing animal gametes
Why do some species employ both mitosis and meiosis, whereas other species use only mitosis?
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92; two chromatids per chromosome
A human bone marrow cell, in prophase of mitosis, contains 46 chromosomes. How many chromatids does it contain?
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they have uncoiled to form long, thin strands
Why is it difficult to observe individual chromosomes with a light microscope during interphase?
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32
Starting with a fertilized egg (zygote), a series of five cell divisions would produce an early embryo with how many cells?
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cytokinesis and mitosis; mitotic phase (M)
Which of these phases encompasses all of the stages of mitosis but no other events?
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the mitotic phase
During \_____ both the contents of the nucleus and the cytoplasm are divided.
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interphase
During \_____ the cell grows and replicates both its organelles and its chromosomes.
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they are sites at which microtubules attach to chromosomes
Which of the following is true of kinetochores?
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G1: follows cell division
Which of the following correctly matches a phase of the cell cycle with its description?
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large cells containing many nuclei
In some organisms, such as certain fungi and algae, cells undergo the cell cycle repeatedly without subsequently undergoing cytokinesis. What would result from this?
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duplicated chromosomes attach to the plasma membrane
Which of the following is found in binary fission but not in mitosis?
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cleavage
Cytochalasin B is a chemical that disrupts microfilament formation. How would this interfere with cell division?
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centrosome
Where do the microtubules of the spindle originate during mitosis in animal cells?
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the formation of the mitotic spindle
Taxol is an anticancer drug extracted from the Pacific yew tree. In animal cells, Taxol disrupts microtubule formation by binding to microtubules and accelerating their assembly from the protein precursor, tubulin. Surprisingly, this stops mitosis. Specifically, Taxol must affect \_____.
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16; 16
A group of cells is assayed for DNA content immediately following mitosis and is found to have an average of 8 picograms of DNA per nucleus. How many picograms would be found at the end of S and the end of G2?
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a groove in the plasma membrane between daughter nuclei
What is a cleavage furrow?
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radioactive-labeled nucleotides
Using which of the following techniques would enable your lab group to distinguish between a cell in G2 and a cell from the same organism in G1?
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E
What is the correct chromosomal condition for one daughter nucleus at telophase of mitosis?
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formation of telophase nuclei
If the cell whose nuclear material is shown in the figure continues toward completion of mitosis, which of the following events would occur next?
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gamma contains more DNA than beta
Of the following, the best conclusion concerning the difference between the S phases for beta and gamma is that \_____.
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are actually in the G0 phase
The best conclusion concerning delta is that the cells \_____.
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cell cycle checkpoints are not in place to stop cells with chromosome abnormalities
Cells from advanced malignant tumors often have very abnormal chromosomes as well as an abnormal number of chromosomes. What might explain the association between malignant tumors and chromosomal abnormalities?
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- cigarette smoke
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- testosterone
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- UV light
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- fat
Are carcinogens
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any substance capable of causing cancer in living tissue
Carcinogen
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Fat
\_____ is a carcinogen that promotes colon cancer.
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G1
Cells will usually divide if they receive the proper signal at a checkpoint in which phase of the cell?
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they remain confined to their original site
Which of the following is true of benign tumors, but not malignant tumors?
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Cdk
Which of the following is a protein maintained at constant levels throughout the cell cycle that requires cycling to become catalytically active?
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cyclin
Which of the following is a protein synthesized at specific times during the cell cycle that associates with a kinase to form a catalytically active complex?
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activating a process that destroys cyclin components
The MPF protein complex turns itself off by \_____.
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Cdk is present throughout the cell cycle and is an enzyme that attaches phosphate groups to other proteins
Which of the following describe(s) cyclin-dependent kinase (Cdk)?
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when they stop dividing, they do so at random points in the cell cycle; they are not subject to cell cycle controls; and they do not exhibit density-dependent inhibition when growing in culture
Which of the following is true concerning cancer cells?
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infection causes lymphocytes to divide more rapidly
Nucleotides can be radiolabeled before they are incorporated into newly forming DNA and can therefore be assayed to track their incorporation. In a set of experiments, a student-faculty research team used labeled T nucleotides and introduced these into the culture of dividing human cells at specific times.
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The research team used the setup to study the incorporation of labeled nucleotides into a culture of lymphocytes and found that the lymphocytes incorporated the labeled nucleotide at a significantly higher level after a pathogen was introduced into the culture. They concluded that \_____.
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suffering from cervical cancer
When cells were first taken from Henrietta Lacks, she was \_____.
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cells were taken while she was being treated for cancer many years ago, and these cells have been cultured in the lab ever since
How did doctors harvest and culture cells from Henrietta Lacks?
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she was never told that her cells were being taken, and neither she nor her family has been compensated
Did doctors ask Henrietta Lacks' permission to take her cells, and was she paid for them?
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they continue to divide and multiply after decades of culture
What property of Henrietta Lacks' cells was most unusual when they were grown in the laboratory?
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- the development of a polio vaccine
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- new treatments for cancer
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- tests of the effects of atomic radiation on life
Cells taken from Henrietta Lacks have been used for experiments leading to \_____.
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III
MPF reaches its threshold concentration at the end of this stage.
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it interferes with rapidly dividing cells
For a chemotherapeutic drug to be useful for treating cancer cells, which of the following is most desirable?
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separase enzyme cleaves cohesins and allows chromatids to separate
At the M phase checkpoint, the complex allows for what to occur?
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Bacteria Only:
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- chromosome separation begins at the origin of replication on DNA
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Eukaryotes Only:
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- before separation duplicated chromosomes condense
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- nuclear envelope fragments permitting chromosome separation
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- two copies of the duplicated chromosome are attached at their centromeres before separating
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Both Bacteria and Eukaryotes:
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- chromosomes replicate before cell division
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- replicated chromosomes separate by attaching to some other structural feature of the cell
In all cells, separation of replicated chromosomes is a prerequisite for cell division. However, the mechanism of chromosome separation in bacteria is distinct from that in eukaryotes in several ways.
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- the cell plate consists of the plasma membrane and cell wall that will eventually separate the two daughter cells
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- vesicles from the Golgi apparatus move along microtubules, coalesce at the plane of cell division, and form a cell plate
Which of the following statements are true of cytokinesis in plant cells?
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true; true; false
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false; false; true
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true; false; true
Plant and animal cells also require cytoskeletal proteins for cytokinesis, although the roles these proteins play differ among bacteria, plants, and animals.
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For each space in the table, drag the appropriate label to indicate if the statement is true or false for each group of organisms.
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cytokinesis when the cytoplasm divides forming two new cells
Select the part of the cell cycle where the cell actually produces two new identical cells.
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as cells become more numerous, the amount of required growth factors and nutrients per cell becomes insufficient to allow for cell growth
Density-dependent inhibition is a phenomenon in which crowded cells stop dividing at some optimal density and location. This phenomenon involves binding of a cell-surface protein to its counterpart on an adjoining cell's surface. A growth inhibiting signal is sent to both cells, preventing them from dividing. Certain external physical factors can affect this inhibition mechanism. Select the statement that makes a correct prediction about natural phenomena that could occur during the cell cycle to prevent cell growth.
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meiosis
Human gametes are produced by \_____.
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23
Normal human gametes carry \_____ chromosomes.
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16
A diploid organism whose somatic (nonsex) cells each contain 32 chromosomes produces gametes containing \_____ chromosomes.
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produces offspring genetically identical to the parent
Asexual reproduction \_____.
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44 autosomes and 2 sex chromosomes
What number and types of chromosomes are found in a human somatic cell?
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include genes that determine an individual's sex
The human X and Y chromosomes \_____.
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sporophyte
In alternation of generations, what is the diploid stage of a plant that follows fertilization called?
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homologous chromosomes contain the same gene loci but may have different alleles of a particular gene. Sister chromatids are identical copies of each other produced during DNA replication
How are sister chromatids and homologous chromosomes different from each other?
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each cell has eight homologous pairs
Which of the following is true of a species that has a chromosome number of 2n \= 16?
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63 chromosomes in 21 sets of 3
A triploid cell contains three sets of chromosomes. If a cell of a usually diploid species with 42 chromosomes per cell is triploid, this cell would be expected to have which of the following?
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a plantlike protist
Which of the following can utilize both mitosis and meiosis in the correct circumstances?
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an error in either egg or sperm meiotic anaphase
Which of the following might result in a human zygote with 45 chromosomes?
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two diploid cells ... four haploid cells
Mitosis results in the formation of how many cells; meiosis results in the formation of how many cells?
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synapsis occurs
Which of the following occurs during meiosis but not during mitosis?
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the exchange of homologous portions of nonsister chromatids
What is crossing over?
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it has half the amount of DNA as the cell that began meiosis
If a cell has completed the first meiotic division and is just beginning meiosis II, which of the following is an appropriate description of its contents?
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haploid, and the chromosomes are each composed of two chromatids
After telophase I of meiosis, the chromosomal makeup of each daughter cell is \______.
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the statement is true for mitosis and meiosis II
Chromatids are separated from each other.
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the statement is true for meiosis I and meiosis II
A cell divides to produce two daughter cells that are genetically different.
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four sister chromatids
A pair of homologous chromosomes includes which of the following sets of DNA strands?
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3
The following question refers to the essential steps in meiosis described below.
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1. Formation of four new nuclei, each with half the chromosomes present in the parental nucleus
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2. Alignment of tetrads at the metaphase plate
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3. Separation of sister chromatids
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4. Separation of the homologs; no uncoupling of the centromere
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5. Synapsis; chromosomes moving to the middle of the cell in pairs
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Which of the steps takes place in both mitosis and meiosis?
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one chromosome 12 with one blue gene and one chromosome 19 with one long gene
A certain female's number 12 chromosomes both have the blue gene and number 19 chromosomes both have the long gene. As cells in her ovaries undergo meiosis, her resulting eggs (ova) may have which of the following?
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one-half blue short and one-half orange short gene eggs
If a female of this species has one chromosome 12 with a blue gene and another chromosome 12 with an orange gene, and has both number 19 chromosomes with short genes, she will produce which of the following egg types?
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-random fertilization
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-independent assortment of chromosomes in meiosis
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-crossing over
Which processes lead to most genetic variation in sexually reproducing organisms?
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B and C
Which of these gametes contains one or more recombinant chromosomes?
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meiosis
The shuffling of chromosomes that occurs during both fertilization and \_____ can lead to genetic variation.