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These flashcards cover key concepts related to cell signaling, including receptor types, signal transduction pathways, and communication methods.
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Ligand-gated ion channels
Receptors located in the plasma membrane that open or close in response to the binding of a ligand, allowing for the diffusion of specific ions.
G protein coupled receptors (GPCRs)
The largest category of cell surface receptors that, upon ligand binding, activate G proteins to initiate a cellular response.
Signal transduction pathways
The series of molecular events and chemical reactions that lead to a cellular response following the reception of a signal.
Reception
The first stage of cell signaling where a ligand binds to a receptor.
Transduction
The conversion of an extracellular signal to an intracellular signal within a cell.
Response
The final stage in cell signaling where the cellular process is altered as a result of the signal received.
Local signaling
Communication between cells that occurs over short distances, such as paracrine and synaptic signaling.
Long-distance signaling
Communication between cells that occurs over long distances, typically through hormones.
Second messengers
Small, non-protein molecules that amplify the signal in a signal transduction pathway.
Chemical stimulus
An external signal that can cause a ligand to bind to receptors, influencing the behavior of cells.