Red Flags/Adverse Reactions

Amoxicillin

Watery or bloody diarrhea

mouth pain

Vaginal burning, itching, discharge

Allergic reaction: rash ,sob, wheezing, swelling of mouth, tongue or lips

Cephalexin

C-diff

Bleeding

Alergic reactions: rash/hives, anaphylaxis

Thrombophlebitis

DIsulfiram-like reaction of taken with alcohol

Aztreonam

Pain

Thrombophlebitis and inflammations at IV site

Wheezing, nasopharyngeal pain with inhalation

Imipenem

Thrombophlebitis

penicillin or carbapenem allergy

seizure disorder

renal impairment

Vancomycin

toxicity - renal failure

With rapid infusion - Red Man Syndrome (tachycardia, hypotension, rash, pruritus, urticaris, flushing

ototoxicity ( tinnitus, hearing loss, vertigo and balance issues)

tetracyclines

hepatotoxicity (stomach pain, N/V, fatigue, jaundice loss of appetite, dark urine)

photosensitivity - easily sunburned

Discolor teeth

breaks down both ( dont take if prego or <8 yo)

erythromycin

ventricular dysrhythmias

Ototoxicity - hearing loss, vertigo, tinnitus

Gentamicin

Ototoxicity - headache, ataxia, vertigo, tinnitus

Nephrotoxicity- fluid retention, decreased urine output, hypertension

Ciprofloxacin

CNS - dizziness and headache, confusion

rupture of achilles tendon

photosensitivity

seizures

increased intracranial pressure

suicidal ideation

hepatotoxicity

trimethoprim and sulfamethoxazole

renal damage - crystalluria

superinfection - c-diff

steven-johnson syndrome

Blood Dyscrasias (agranulocytosis, aplastic anemia, thrombocytopenia

Nitrofurantoin

Pulmonary distress (dyspnea, chest pain, chills, cough, sob, fever)

Pulmonary fibrosis

peripheral neuropathy

Blood Dyscrasias

discolored urine

liquid form can stain teeth

isoniazid

Hepatotoxicty and liver damage

peripheral neuropathy

CNS - dizziness, ataxia, seizures psychosis

DRESS 9rash, facial swelling, lymphadenopathy, eosinophilla, atypical lymphocytosis

Rifampin

urine salvia, tears , and sweat may turn red-range

liver toxicty

hepatitis

metronidazole

heart, liver, renal failure

N/V, diarrhea

metallic taste anorexia dry mouth

darkening of urine

seizure disorders

CNS ( Ha, vertigo, ataxia)

teratogenic

history of blood disorders

chloroquine

visual symptoms

Nausea and Diarrhea

liver disease

Amphotericin B

infusion reaction( chills, fever, nausea, tachycardia, hypotension, headache)

renal toxicity

red blood cell suppression

thrombophlebitis

ketoconazole

topical=burning itching, redness, and localized hypersensitivity

liver toxicity

N/V, constipation, diarrhea

drowsiness, dizziness

Acyclovir

topical = buring, itching at application site

N/V, diarrhea

headache, vertigo

renal, cns toxicity

thrombophlebitis

thrombophlebitis

inflammation of a vein often caused by blood clots

ataxia

lack of muscle coordination, clumsy movement

DRESS

Druf Reaction with Eosinophilia and Systemic Symptons

Pulmonary Fibrosis

scarring and thickening of lung tissue, making it difficult to breathe

blood dyscrasias

abnormality in the components of the blood

agranulocytosis

severe reduction in granulocytes (wbc) leading to increase susceptibility to infections

aplastic anemia

bone marrow doesn’t produce enough rbc, wbc, and platelets

thrombocytopenia

low platelet number in blood can cause bleeding

tinnitus

ringing, buzzing or clinking in the ear

nephrotoxicity

kidney damage from exposure to toxic substances

pruritus

itching

urticaria

skin condition, itchy red raised welt or bumps in the skin

c-diff

diarrhea and colitis(inflammation of colon)

Stevens-johnsons syndrome

severe life-threatening skin reaction, painful rash, blisters and skin peeling

crystalluria

crystals in the urine