Cell migration steps

what is the first step in cell migration

name the regulators in this steps and say where they are (either front or side or rear)

cell polarisation

SIDE / REAR

PTEN, MYOSIN 2

FRONT

activated CDC42, RAC

PIP3

activated integrin

MTOC/GOLGI

MTs

CDC42, PARS, aPKC

what is at the rear in cell polarisation

wat step in the process is this

SIDE / REAR

PTEN, MYOSIN 2

first step

WHAT IS AT THE FRNT OF CELL THE IN CELL POLARISATION

CDC42, PAR proteins, aPKC, involved in generation of polarity intrisnic to migration

FRONT

activated CDC42, RAC

PIP3

activated integrin

MTOC/GOLGI

MTs

CDC42, PARS, aPKC

what is organised at front of nucleus

MTs and MTOC and nucleus

what is

CDC42

MTOC

RAC

RHO

PTEN

CDC42: cell division control protein 42 homolog- small Rho GTPase family- FOUND AT PM and GA

MTOC- MT organising complex

RAC-rHO FAMILY gtpASES

RHO

PTEN