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Components of cytoskeleton
Actin
tubulin
protofilament
Functions of cytoskeleton
Structure and support
Intracellular transport
Contractility and mobility
Spatial organization
Skeletal muscles
a-actin
Cardiac muscles
b-actin
Smooth muscles
a & b actin
non-muscle tissues
y-actin
Mechanisms of sliding filament theory
Myosin cross-bridge attaches to actin myofilament
Myosin head pivots and pulls on the actin filament (ADP +Pi released)
New ATP attached to myosin head, cross bridge detaches
ATP hydros used, erecting the myosin head
Amoeboid migration
Most common mode of locomotion in eukaryotic cells
caused by the protrusion of cytoplasm of the cell involving the formation of pseuopodia
