Granulomatous Inflammation (Leziel done q & a)

1. Feature of a case of active pulmonary granuloma

2. Duration of granuloma development

3. Infectious cause of pulmonary granulomas

4. Granulomatous inflammation in this lung can lead to __ necrosis

Numerous confluent granulomas

Months to years

Tuberculosis

Caseous Necrosis

1. Grossly, a granuloma tends to be a ___ lesion

2. Location example of granuloma

3. What type of necrosis happening? due to?

Focal Lesion

Hilar Lymph Node

Caseous Necrosis, Mycobacteria

1. Distribution of focal nature of granulomas in lung parenchyma

2. Radiographic pattern of granulomatous disease

3. Key microscopic features of a granuloma

Scattered

Reticulonodular

Pale pink central caseous necrosis, Dark blue lymphocytes, Elongated epithelioid cells, Multnucleated Langhans giant cells.

1. Location example of pulmonary granuloma

2. Cellular composition of granulomatous inflammation

Bronchiole

Epithelioid macrophages, Langhans giant cells, lymphocytes, plasma cells, fibroblasts, neutrophils

1. Cause of granulomatous inflammation

2. Typical morphology of granuloma

3. the fungus known as Coccidioides immitis, giant cell in the center, presents 

Persistent agents

Rounded and focal nature

Spherules

Ren