Exam 2- Ultraviolet

What is the use of artificial UV light for therapeutic purposes?

Phototherapy

What is the use of artificial UV light with a chemical photosensitizing agent for therapeutic purposes?

Phtochemcial effect

Physiological and therapeutic effects of UV light?

Induce skin erythema response

Inhibit epidermal hyper proliferation

Enhance apoptosis

Induce local immunosuppression

Decrease cutaneous cell turnover

Increase vitamin B production

Ultraviolet radiation is absorb in the first _______ of skin

1-2mm

The physiological effects of UV radiation are?

Very superficial

-alters cell biochemistry

-cell damage and death

-inflammatory reaction

-increased capillary permeability

How do you determine the does of UV radiation?

Minimal erythma dose

Estimate based on Fitzpatrick`s Skin Phototype

Why is UV light not used much for healing?

It's photogermicidal

-meaning it can kill the bacteria but also kill the tissue it is trying to heal too

What is UV radiation used for?

Clearance of psoriasis

Clearance of atopic dermatitis or eczema

Regimentation vitiligo

What are some photosensitivity agents

Psoriasis- psoralen

Creams and oral meds

Contraindications of UV radiation

Over the eye

Malignant skin

History of melanoma

SLE, Porphyria's, pellagra sarcoidosis, herpes simplex

Active tuberculosis

Kidney, cardiac, and liver disease

Hyperthyroidism

Diabetes mellitus

Acute eczema or dermatitis

Risks of UV radiation

Areas recently exposed to other radiation's

Fever

Large dose

Children's

Pregnant or lactating

Photosensitizing drugs