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31 Terms

1
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Body system including skin, hair, nails, and glands that protects, regulates temperature, and maintains homeostasis.

Integumentary System

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The largest organ of the human body, covering about 2 square meters in adults; composed of the epidermis and dermis.

Skin

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The thin, outer layer of the skin made mostly of keratinized epithelial cells; lacks blood vessels and nerves.

Epidermis

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The thicker inner layer of the skin made of connective tissue and collagen fibers; contains nerves, blood vessels, and glands.

Dermis

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A fatty connective layer beneath the dermis that insulates and cushions the body.

Hypodermis (Subcutaneous Layer)

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Main cells of the epidermis that produce keratin, giving skin strength and waterproofing.

Keratinocytes

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Pigment-producing cells in the epidermis that make melanin for UV protection and skin color.

Melanocytes

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Glands that secrete sebum to lubricate and waterproof the skin and hair.

Sebaceous (Oil) Glands

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Glands that secrete sweat to regulate temperature and remove waste through evaporation.

Sweat (Sudoriferous) Glands

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Structures in the dermis that produce hair and contain stem cells that assist in skin regeneration.

Hair Follicles

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The process by which the skin helps regulate internal body balance, including temperature and water loss.

Homeostasis

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A wound that affects only the epidermis; healed by rapid epithelial cell division.

Shallow Cut

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A wound extending into the dermis or subcutaneous layer; triggers bleeding and clot formation.

Deep Cut

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A mesh of fibrin, blood cells, and platelets that seals a wound and prevents fluid loss.

Blood Clot

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Dried tissue fluid and clot that forms a protective layer over a healing wound.

Scab

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A protective response where blood flow increases and macrophages clean up debris and pathogens.

Inflammation

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Phagocytic white blood cells that remove dead cells and bacteria during wound healing.

Macrophages

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Connective tissue cells that secrete collagen fibers to strengthen and bind a wound.

Fibroblasts

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Strong protein strands in the dermis that provide structural support and help form scar tissue.

Collagen Fibers

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Stage of healing when epithelial cells multiply and new tissue forms.

Proliferation Phase

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Final healing stage where tissue strengthens and the scab falls off; scars may form.

Remodeling (Maturation) Phase

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Superficial burn damaging only the epidermis; causes redness and mild pain; heals without scarring.

First-Degree Burn

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Burn damaging the epidermis and part of the dermis; produces blisters and pain; heals with little or no scarring.

Second-Degree Burn

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Full-thickness burn destroying epidermis, dermis, and accessory structures; may require skin grafts.

Third-Degree Burn

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A medical procedure transferring healthy skin to cover a severe burn or wound.

Skin Graft

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A method for estimating the percentage of body surface area affected by burns.

Rule of Nines

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Used to plan fluid replacement, electrolyte management, and treatment for burn patients.

Purpose of Rule of Nines

28
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A pigment produced by melanocytes that gives skin its color and protects against UV damage.

Melanin

29
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Components of the skin such as hair, nails, and glands that assist in protection and regulation.

Accessory Structures

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Regulates body temperature, water balance, and excretion, while protecting internal organs.

Homeostatic Role of Skin

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