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Psychoactive Substance
substance that alters mental ability, mood, or behavior
ex. nicotine, LSD, alcohol
Substance use disorder
A pattern of substance use leading to clinically significant impairment or distress
Symptoms: at least 2, occurring within a 12 month period
number of symptoms of substance abuse
11 symptoms fit into 4 categories
4 categories of substance abuse symptoms
Impaired control
Social impairment
Risky use
Tolerance/Withdrawal
Substance abuse severity
Determined by the number of criteria/symptoms met
mild: 2-3
moderate: 4-5
severe: 6+
Category: Impaired control
Substances used in larger amounts or for a longer amount of time than intended
Wants to stop, reports that they can't
Spends a lot of time getting/using/recovering from effects of substances
Craves substances often
Category: Social impairment
Recurrent substance abuse results in failure to fulfill major obligations (work, school, home etc.)
Continued use despite issues it causes
Important activities might be given up due to substance use
Category: Risky Use
Recurrent substance use in situations where its physically harmful
Continued use of substance use despite knowing that substance may be physiologically or psychologically impairing
Category: Tolerance and Withdrawal
Tolerance:
Marked increased dose of the substance to get the same effect
Reduced effect when the usual dose is consumed
Withdrawal: a set of physiological symptoms a person experiences when drug use is stopped or decreased
Ex. throwing up, feeling sick
These are indicators of physiological dependence
How does cocaine interact with the brain?
It blocks the reabsorption (reuptake) of dopamine
Substance use at UIUC
67.8% of UIUC drank alcohol in the last year (2018)
Alcohol use disorder: prevalence
Age
Highest among young adults (18-29)
Lowest among elderly (65+)
Gender
Men are 5x more likely to chronically use alcohol
Trans individuals show higher use than gen pop
Substance use disorder comorbid with anxiety and depression
Race/ethnicity
Indigenous Americans have highest rates of alcohol abuse and dependence
Alcohol use disorder: etiology - genetic factors
Gender
Males: MZ = 56%, DZ = 33%
Females: MZ = 30%, DZ = 17%
Binary gender differences in alcoholism for MZ and DZ twins could be attributed to:
Women have lower physical tolerance
Negative social attitudes towards public intoxication for women
Cloninger adoption study
Type 1: bio parents had later onset of drinking problems with absence of criminal behavior
Type 2: bio parents had early onset of drinking problems and had undergone treatment or presence of criminal behavior
Children of Type 1 and Type 2 parents were adopted into 2 kinds of homes: heavy drinking and absence of heavy drinking; also had a control group
Results: Type 1 genes increase risk of alcoholism only in the presence of an alcohol household, whereas alcoholism is primarily genetically determined whenever Type 2 genes are present
Results of Cloninger Study (Type 1)
- Without genes, environment didn't make much of a difference in STABLE homes
- Environment played bigger role in Type 1 than Type 2
- High percentage of genetically predisposed had alcoholism in UNSTABLE homes
**G x E Environment**
Results of Cloninger Study (Type 2)
- Having Type 2 genes increased risk for alcoholism REGARDLESS of adoptive father's drinking habits
- Very high rates of alcoholism in children in unstable homes, still larger percentage in stable homes
**PRIMARILY GENETIC EFFECT**
Substance use disorder: etiology - social factors
Cultural/religious influence on early exposure/attitudes
Initial experimentation more likely in rebellious and extraverted or if peers/parents encourage
Increased risk with affiliate with peers who use drugs if unstable home environment, low parental monitoring, systematic problems
Gateway Hypothesis: using one psychoactive substance increases the likelihood of using others
NOT supported by research
Substance use disorder: etiology - psychological factors
Expectations of alcohol
enhances social and physical pleasure
enhances sexual performance
improves mood
reduces tension
increases social assertiveness
Positive expectations have a stronger influence
Operant conditioning: drug use is more likely to continue through positive reinforcement and negative reinforcement
Classical conditioning: “drug cues” elicit conditioned responses through repeated pairings with drug use
Substance use disorder: etiology - common liabilities model
Study followed 7-9th graders into adulthood
Teens who later developed substance abuse were also likely to exhibit other “problem behaviors”
Might stem from the same underlying factors (ex. common liabilities to neurological, psychological, or social factors)
This model tries to explain comorbidity between substances and between psychopathology
What drug seems to be the most addictive?
Tobacco
DARE Program (Drug Abuse Resistance Education)
a common prevention program
not effective in reducing substance use
Pediatric substance abuse
Higher risks than adult substance use:
impacts on developing brain
more likely to cooccur with other risky behaviors
likely to influence future behaviors
Substance abuse disorder: Treatment considerations
most people don't seek treatment
compliance in treatment is low and attrition is high
high comorbidity rate of alcoholism and mental disorders → makes treatment more challenging
(ex: individual with social anxiety disorder might feel more comfortable in social situations after having a few drinks)
detoxification and antabuse
Treatment goals: abstinence vs harm reduction
abstinence: stop taking substance entirely
harm reduction: trying to reduce the harm to the individual and society that may come from substance abuse and dependence
Detoxification (Medical Detox)
- specific to alcoholism
- medically assisted withdrawal
- gradual decrease of alcohol usage over time
Goal of Detoxification
to help wean a person off of alcohol by slow decrease of usage to avoid severe withdrawal symptoms, under doctor's care
Antabuse
medication (pill) that makes body unable to process alcohol, taking Antabuse makes person throw up + other violent symptoms
Why does Antabuse work?
CLASSICAL CONDITIONING
- brain pairs negative outcome of consuming alcohol with violent symptoms, person less likely to consume alcohol
What type of therapy is Antabuse?
Aversion therapy; decreases appeal of drinking through physiological effects
Which of the following is NOT true about Antabuse?
a. It blocks the processing of alcohol by the body.
b. It reduces alcohol cravings by pairing alcohol use with a negative response.
c. It is administered to prevent lethal withdrawal symptoms.
d. It operates under the principles of classical conditioning.
c. It is administered to prevent lethal withdrawal symptoms.
Treatment Goals: Harm Reduction
- minimize harm associated with drug use for the individual or society, valid way to treat
- Ex: recovery programs that distribute clean needles or other things that encourage safe use if individual is going to continue usage, take-home Narcan, supervised consumption facilities
**IDEA: there will always be people that use dangerous substances, would rather create a safe environment to reduce death, no pressure to stop or slow usage**
Motivational Interviewing
A non-judgmental, non-confrontational, non-adversarial approach that attempts to increase clients' awareness of:
potential problems
consequences
risks faced as a result of behavior
Based on 5 general principles:
expressing empathy
developing discrepancy
rolling with resistance
supporting self-efficacy
avoiding argumentation (and direct confrontation)
Other Treatments for Substance Abuse Disorder
CBT
12-step program
Residential treatment
Family therapy
12 Step Program for Substance Abuse
- three main ideas:
1. acceptance: drug addiction is a chronic illness, life has become unmanageable
2. person must surrender giving themselves over to a higher power, big turn-off for a lot of people because many people do not believe in a higher power
3. active involvement with others, have to go to your meetings
Residential Treatment
- dealing with things currently and making plans to help in the future, what it feels like waking up without drinking, removes them from access to substance
Family Therapy
- targeting adolescents, highlights need to introduce family into treatment, address a wide variety of problems in addition to drug problem, how they address conflict, communication, problems with school/peer conflicts
Treatment Outcomes for Substance Abuse
relapse is not uncommon
no one treatment is superior to others
improvements in general health, social, and occupational functioning usually accompany reduction in drug use
positive long-term outcomes are most favorable when:
high degree of coping resources
available social support
low stress situations
Opioid epidemic
Quick summary
700,000 deaths from a drug overdose → 68% of which were opioids
What’s being done:
national public awareness campaign
big fight between law enforcement vs education
Feeding and Eating Disorders
- Anorexia Nervosa
- Bulimia Nervosa
- Binge Eating Disorder
Binge Eating
- someone eats a large amount of food in a short amount of time
- DSM-5 lists as two hours
- larger amount of food being consumed than the average during same time period
- loss of control must be present to meet criteria for a binge in DSM-5
Objective Binge
- eating a lot of food according to scientific standards
- is associated with a loss of control
Subjective Binge
- someone feels loss of control
- person feels that they are eating a lot for THEIR own standards, in reality, not a lot of food
Compensatory Behaviors
- bunch of different behaviors aimed at offsetting food consumption for weight loss
- could be over-exercising
- present in both anorexia and bulimia
Purging
- any behaviors someone participates in to try and get rid of food right after consumption in order to lose weight
- Ex: throwing up, misusing laxatives
The eating behaviors that the young woman in the video describes appear to be an example of...
a. An objective binge
b. A subjective binge
c. Compensatory behaviors
d. Purging
a. An objective binge
Anorexia Nervosa
- Restriction of energy intake, SIGNIFICANTLY low body weight
- Intense fear of gaining weight that does not diminish
- Distorted sense of body shape, undue influence of body weight or shape on self-evaluation, OR lack or recognition of seriousness of low body weight
Anorexia Types
- Restricting type
- Binge-eating/purging type
Restricting type
- Limit the amount of food eaten
- No recurrent episodes of binge eating or purging in the last 3 months
Binge-eating/purging type
- Recurrent episodes of binge eating or purging in the last 3 months
Bulimia Nervosa
- Binge eating (objective)
- Inappropriate compensatory behaviors to prevent weight gain
- Binge eating and compensatory behaviors must occur ONCE a week for 3 months
- Self-evaluation is unduly influenced by body shape and weight
**NOT UNDERWEIGHT, usually normal weight or overweight**
Anorexia Bodily Functions
- low blood pressure
- cold and lethargic
- no energy from starvation
- no fat to keep warm
Lanugo
thin white hair that develops all over the body, body's last resort to maintain body hear because there us little to no fat on body
**ANOREXIA**
Amenorrhea
no menstruation, no symptoms of period aside from blood, used to be required for diagnosis
- PROLONGED AMENORRHEA CAN LEAD TO INFERTILITY
**ANOREXIA**
Pollinia
- electrolyte imbalance that can cause heart failure, kidney failure, and can lead to seizures
- most dangerous part of anorexia
Bulimia Bodily Functions
- repeated vomiting can lead to erosion of tooth enamel, dentist may be first to know
- overly sensitive gag reflex even when not intentional
- swelling in face
- electrolyte imbalance
Further health issues occur from bulimia because...
electrolytes regulate nerve and muscle function and rebuilding damaged tissues, same consequences in anorexia
Electrolyte Imbalance in Bulimia
electrolytes interact with water and hydration over time; someone vomiting and using diuretics will often throw off electrolytes and lose water
Binge Eating Disorder
1. Recurrent binge eating (same as bulimia)
2. Episodes associated with 3 (or more) of there following:
- eating more rapidly that normal
- eating until uncomfortably full
- eating large amounts of food when not physically hungry
- eating alone because of embarrassment
- feeling disgusted with self after binge
3. Marked distress from binge eating is present
4. The binge eating occurs at least ONCE a week for 3 months
*NOT associated with obesity*
Anorexia-Restricting Type Common Features
- Significantly underweight
- No binge eating
- Compensatory behaviors
Anorexia-Binge/Purge Type Common Features
- Significantly underweight
- Binge eating
- Compensatory behaviors
Bulimia Nervosa Common Features
- Normal or overweight
- Binge eating
- Compensatory behaviors
Binge Eating Disorder Common Features
- Normal or overweight
- Binge eating
- No compensatory behaviors
For the last few years, 25 y/o Lauren has struggled with her weight. She constantly wants to lose weight but is never satisfied when she does lose weight. If and when she does eat, she eats large quantities of food. She then exercises for 5 hours and throws up after. Her current BMI is 16 and she is beginning to have issues with her physical health. What eating disorder would she likely be diagnosed with?
(Note: a BMI of 18 to 24.9 is considered healthy for adults)
a. Bulimia Nervosa
b. Binge Eating Disorder
c. Anorexia Nervosa, Restrictive subtype
d. Anorexia Nervosa, Binge Purge subtype
d. Anorexia Nervosa, Binge Purge subtype
For the last few years, 23 y/o Chelsea has been struggling with her body image. At least once a week, she will eat large quantities of food (> 3,000 calories) in one sitting and then will exercise for 5 hours and take laxatives in order to prevent weight gain. Her current BMI is 27. What eating disorder would she likely be diagnosed with?
(Note: a BMI of 18 to 24.9 is considered healthy for adults)
a. Bulimia Nervosa
b. Binge Eating Disorder
c. Anorexia Nervosa, Restrictive subtype
d. Anorexia Nervosa, Binge Purge subtype
a. Bulimia Nervosa
Eating Disorder Social Factors
- Prevalence in U.S. increased with thin ideals
- Media effects
- More common in career fields emphasizing thinness
- Gender stereotypes
- Standards of beauty
- Peer groups
- Pro-Ana websites, #thinspo
Pro-Ana
blogs, chat forms, TikTok pages, any online source that supports a form of disordered eating; these websites strengthen disease of anorexia and praise weight-loss, discourage healthy body shapes and sizes
Eating Disorders Biological Factors
- Genetics; high heritability, weight set points
- Brain differences; decreased functioning of hypothalamus, differences in serotonin
- Poor interoceptive awareness
Decreasing functioning of the hypothalamus is associated with
hunger
Decreased seratonin can lead to
cravings of carbs; more likely to engage in binge
Interoceptive
being aware of internal body cues
Eating Disorders Personality and Cognition
- excessive concern of opinions of others, need to please (socialized for women)
- struggle with control
- high perfectionism
- neuroticism
- impulsivity
Which of the following is NOT a health complication often associated with bulimia?
a. Electrolyte imbalance
b. Lanugo
c. Dehydration
d. Eroded tooth enamel
b. Lanugo
Eating Disorders - Family
- Low parental warmth and high demands
- Enmeshment
- Overprotectiveness
- Rigidity: Avoid dealing with events that require change
- Conflict avoidance or lack of resolution
- Modeling preoccupations or direct messages about thinness
Enmeshment
an extreme form of over-involvement and intimacy in family
*more common in anorexia
Ex: parents do not allow closed doors in house
Overprotectiveness
an extreme level of concern for each other's welfare
*more common in anorexia
Eating Disorders Maintenance Factors: Emotion
- Binge eating is a way to deal with negative emotions (NEGATIVE REINFORCEMENT)
- Research shows that negative emotions are higher immediately after binge eating
Eating Disorders Dieting
Dietary restraint - overly restrictive eating predicts binge eating
- overly restrictive diet -> hunger, frustration -> increased risk of binge eating
*strict dieting is likely to contribute to subsequent binge-eating especially in those with bulimia*
Lucas has episodes 2x a week in which he orders 3 chili cheese dogs, French fries, 2 large chocolate cake shakes, and a strawberry shortcake. He eats everything in 1 hour. After each episode, he spends the rest of that day running on a treadmill (5+ hours) and spends the next few days fasting and avoiding all food in order to avoid weight gain. His BMI is 23. What eating disorder best represents Lucas' experiences?
a. Bulimia Nervosa
b. Binge Eating Disorder
c. Anorexia Nervosa, Restrictive subtype
d. Anorexia Nervosa, Binge Purge subtype
e. None of the above
a. Bulimia Nervosa
Anorexia Nervosa Epidemiology
- Cisgender women: ~1% lifetime prevalence
- Cisgender men: ~0.3% lifetime prevalence
- Trans folks: 2x-4x the prevalence
- Non-binary folks: mixed results; greater or comparable risk to trans folks
Bulimia Nervosa Epidemiology
- Cisgender women: ~1.5% lifetime prevalence
- Cisgender men: ~0.5% lifetime prevalence
(trans/non-binary stats consistent across all ED's)
Binge Eating Disorder Epidemiology
- Cisgender women: ~3.5% lifetime prevalence
- Cisgender men: ~2% lifetime prevalence
(trans/non-binary stats consistent across all ED's)
Eating Disorders Intersectionality
- Higher risk for individuals who identify as having experienced marginalization or discrimination
- Racial identity and gender identity interact in U.S.
- Only difference in binge eating disorder in Asian Americans/Pacific Islanders
Eating Disorder Epidemiology and Culture
- Anorexia found in many cultures throughout history
- Bulimia occurs in same frequencies in industrialized countries
- White women at greatest risk for disordered eating
- Culture appears to have a stronger effect on the prevalence of bulimia versus anorexia
Necessary Steps for Treating Eating Disorders
- Multidisciplinary approach is necessary
- Dietician, psychiatrist, general practitioner
- Need to make sure dietary needs are met
- Hospitalization is often necessary for anorexia
Goals of Treatment of Anorexia
2 major goals
- weight gain
- address difficulties that maintain the problem
- Interpersonal relationships
Challenges to Treatment of Anorexia
- Ego-syntonic issues of pride; fear of weight gain
Which of the following is the etiological factor for eating disorders that describes family members' excessive togetherness and weak family boundaries?
a. Interoceptive awareness
b. Rigidity
c. Enmeshment
d. Overprotectiveness
c. Enmeshment
As a teenager, Cori began perceiving their body negatively, fearing weight gain, and spending much of their time researching "fat-burning" exercise, restrictive diets, and "cleanses". Cori began denying themself enough food and excessively exercising such that their BMI went from 25 to 20 within a school year. At this time, they would be diagnosed with ______________. However, over the next 12 months they start to misuse laxatives after eating and their BMI drops to 17. Following, they would receive a diagnosis of ______________.
(Note: a BMI of 18 to 24.9 is considered healthy for adults.)
a. No diagnosis; Anorexia Nervosa - binge/purge type
b. Anorexia Nervosa - restricting type; Anorexia Nervosa - binge/purge type
c. No diagnosis; Anorexia Nervosa - restricting type
d. Bulimia Nervosa; Anorexia Nervosa - binge/purge type
a. No diagnosis; Anorexia Nervosa - binge/purge type
Two Primary Family Intervention Approaches for Anorexia
- Maudsley approach
- Minuchin approach
Maudsley Approach
- separates child from illness, provide support to parents
- MULTIPLE PHASES:
- First phase: parents take complete control over child's eating
- Second phase: control is gradually shifted back to child
- Third place: child gains proper autonomy towards eating
Minuchin Approach
- (ENMESHMENT) therapy that specifically focuses on enmeshment; helps parents adopt developmentally appropriate behaviors
- Ex: parents originally did not allow closed doors in house; parents now allow closed doors in house
**AIMS TO CHANGE FAMILY BEHAVIOR TO HELP HEAL EATING DISORDERS**
Common Outcomes of Eating Disorders
9% die from eating disorder illness
Bulimia Nervosa: Treatment
- Occurs mostly in outpatient settings in individual, group, or combination therapy
- Nutritional intervention (instructions on modifying eating patterns) and meal planning
Bulimia Nervosa Treatment Goals
- Stabilization of eating patterns
- Address maintenance factors such as emotional dysregulation, interpersonal relationships, etc.
Bulimia Nervosa CBT Example
works to collaboratively identify maintenance factors, introduce regular eating
(ex:
BEFORE therapy: breakfast-skip;
lunch-green salad;
snack-skip;
dinner-binge.
AFTER therapy:
breakfast-cereal w/ milk;
lunch-green salad;
snack-granola;
dinner-steak and potatoes)
Abstinence Violation Effect
negative effects when someone has been avoiding an activity, "cheats", and then engages in indulging too much
Bulimia Nervosa CBT
1. Collaboratively identity maintenance factors, introduce regular eating
2. Address maintenance factors
3. Focus on the future
- exposure to "forbidden" foods and preventing purging behaviors; similar treatment in OCD
- Abstinence violation effect
Bulimia Nervosa Interpersonal Therapy
- originally developed for depression
- focus on themselves and their lives
Biological Treatment for Eating Disorders
antidepressants are somewhat effective
Comparing Treatments for Eating Disorders
- Success rates treating bulimia higher than anorexia treatment rates
- 70% of people with bulimia show complete improvement from symptoms
- CBT is superior to medication at preventing relapse for BN and BED
- For youth, family therapy superior to individual therapy for treating youth with eating disorders
**COMBINATION THERAPY IS THE BEST APPROACH**
Childhood and Mental Health Disorders
- Autism Spectrum Disorder
- Attention-Deficit/Hyperactivity Disorder