Adaptive Immunity

Major histocompatibility antigens are

autoantigens involved in epitope recognition.

Which of the following statements about T lymphocytes is FALSE?

T lymphocytes produce antibody molecules.

The perforin-granzyme pathway involves

the production of special cell-killing proteins that act on infected or abnormal cells.

Which of the following statements concerning the chemical structure of an antibody is FALSE?

The heavy and light chains are connected by hydrogen bonds.

The lymphocytes of adaptive immunity called ________ mature in the red bone marrow.

B cells

IgE antibodies are best described as

a cause of basophil and eosinophil degranulation.

What type of immunity is produced by the body when a person contracts a disease?

naturally acquired active immunity

Which of the following statements concerning plasma cells is FALSE?

They live for many years and function as memory cells.

The antibody-binding site of an antibody is made up of

the variable regions of both light and heavy chains.

Enhanced immune responses to subsequent exposures to an antigen to which the body has already been exposed are known as ________ responses.

memory

Which of the following is a characteristic of the third line of defense that makes it significantly different from the second line?

The response is specific to a single antigen.

Class II MHC are found on

professional antigen-presenting cells.

Exogenous antigens are processed for immune recognition by ________ cells.

dendritic and macrophage

Which of the following statements regarding the lymphatic system is FALSE?

The lymphatic vessels contract to move lymphatic fluid.

Clonal deletion of developing T lymphocytes takes place in which location(s) in the body?

the thymus

Class I MHC molecules are essential for

presentation of endogenous antigens.

Which of the following statements about lymphocytes is FALSE?

B and T lymphocytes can be differentiated using a bright-field light microscope.

The most prevalent antibody class in the blood is

IgG.

Cell-mediated immunity is a function of

T lymphocytes.

Adaptive immunity is sometimes also called acquired immunity. Which of the following statements provides a basis for the alternative name?

To become activated, lymphocytes require exposure to the epitope for which they are specific.

The type of immunoglobulin illustrated in Figure 16.1 is

IgM.

The white blood cells primarily responsible for adaptive immunity are

B lymphocytes and T lymphocytes.

Which of the following is the result when a CTL (cytotoxic T cells) interacts with a virally infected cell?

The cell undergoes apoptosis.

Which of the following function in agglutination?

IgA and IgG antibodies

What is the result when a dendritic cell phagocytizes a microbe and processes it?

display of microbial epitope-MHC II complexes on the cell surface