Trueperella, Rhodococcus, Listeria, and Erysipelothrix

Trueperella pyogenes

Rhodococcus equi

What bacteria are in the Actinobacteria phylum?

Listeria

Erysipelothrix rhusiopathiae

What bacteria are in the Firmicutes phylum?

Pleomorphic gram + coccobacilli that don't form spores

What kind of bacteria are Trueperella pyogenes?

Capnophiles - facultative anaerobes on enriched media

What environment do Trueperella pyogenes grow best in?

Commensal bacteria of mucus membranes (Opportunistic pathogens)

Trueperella pyogenes are considered ____?

Contagious mastitis

Trueperella pyogenes is a common agent in contagious ____ in cows?

Hematogenous dissemination

Trueperella pyogenes can cause lesions all over the body, how does it get around?

Pyrolysis O - cytotoxic to WBC and RBC

Neuraminidase - adhesions

What are the virulence factors of Trueperella pyogenes?

Fusobacterium necrophorum

Trueperella pyogenes often acts as a synergistic pathogen in bovine liver abscesses w/ what organism?

Septic arthritis - pigs

Severe mastitis - Cattle

Trueperella pyogenes causes ___ in swine and ___ in cattle?

Drain abscess

Antibiotics (not well responded to in vivo)

What is tx for Trueperella pyogenes?

gram positive facultative intracellular coccobacillus

What kind of bacteria is Rhodococcus equi?

Oppurtunistic of young foals (commensal of GI tract)

What will Rhodococcus equi primarily effect?

Inhalation/ ingestion of virulent strains from contaminated soil

How do most foals get Rhodococcus equi?

Pyogranulomatous bronchopneumonia

What will Rhodococcus equi cause?

Vap proteins allow it to live in marophages

Capsule

Mycolic acids

Cholesterol oxidase

What are virulences factors of Rhodococcus equi?

Rifampin and Macrolide

Supportive care

How do you tx Rhodococcus equi?

Gram +,

non-spore forming,

Coccobacilli

Facultative intracellular

Listeria monocytogenes is what kind of bacteria?

Blood agar - facultative anaerobe - capnophile

Listeria monocytogenes grows best in what environment?

Ingested of contaminated food

Vertical transmission in Utero

How is Listeria monocytogenes transmitted?

Lymph,

Blood

CNS via nerves

How does Listeria monocytogenes travel in the body?

Brainstem - encephalitis

Septicemia - organ necrosis

Fetus abortions

Where will we see lesions w/ Listeria monocytogenes?

Listeriolysin O

What are the virulence factors of Listeria monocytogenes?

Ruminants

Listeria monocytogenes most commonly affects what animals?

Penicillin

Oxytetracyclines

How do you Tx Listeria monocytogenes?

Gram +

Non spore forming

Rods/ filaments

Erysipelothrix rhusiopathiae is what kind of bacteria?

Faculatative anaerobes - Enriched media

Where will Erysipelothrix rhusiopathiae grow best?

Pigs - tonsils/ GI tract

What is an important reservoir for Erysipelothrix rhusiopathiae?

Via blood stream, causes vascular damage and hemoragic lesions in tissues and joints

How does Erysipelothrix rhusiopathiae travel through the body?

Neuraminidase - adhesins

Hyaluronases - invasins

Capsules

What are virulence factors of Erysipelothrix rhusiopathiae ?

Abortion

Endocarditis

Arthritis

Erysipelothrix rhusiopathiae can cause what lesions?

Zoonotic

Erysipelothrix rhusiopathiae can be ____ which makes it an occupational hazard?

Penicillin (resistant to tetracyclines)

What is the DOC for Erysipelothrix rhusiopathiae ?