Macrolides
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Last updated 11:44 AM on 12/22/25
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5 Terms
1
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Uses
Alternate to penicillin
Treating streptococci
Work better on Gram positive
RTI, STIs, GI, SSTI
Oral
Treating streptococci
Work better on Gram positive
RTI, STIs, GI, SSTI
Oral
2
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Examples
Erythromycin, Clarithromycin
3
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MOA
Binds to 23s rRNA 50s subunit
Reducing translocation
Reducing translocation
4
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Side effects
C.diff risk, GIT direct and indirect
Jaundice
Reversible ototoxicity
Jaundice
Reversible ototoxicity
5
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Dosing
4x daily Erythromycin, 2x daily Clarithromycin
Note 
Flashcards (39)