Macrolides

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Description and Tags

Aerospace Engineering

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5 Terms

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Uses
Alternate to penicillin

Treating streptococci

Work better on Gram positive

RTI, STIs, GI, SSTI

Oral
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Examples
Erythromycin, Clarithromycin
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MOA
Binds to 23s rRNA 50s subunit

Reducing translocation
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Side effects
C.diff risk, GIT direct and indirect

Jaundice

Reversible ototoxicity
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Dosing
4x daily Erythromycin, 2x daily Clarithromycin