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Water Content of the Body (Differences in populations)
Accounts for approx 60% of adult weight
Varies with sex, body mass and age
Men have more water content than women, because men have more lean tissue (less fat cuz fat contains less water than lean tissue)
Infants have a body water content of approx 70-80% while older adults have a content of approx 45-55%. This makes both populations more vulnerable to fluid-related problems.
Functions of Body Water (6)
In constant motion.
Transport nutrients, electrolytes and O2 to cells and carry waste away.
Regulate body temp
Lubricates joints and membranes
Medium for food digestion
Water shifts between compartments
Body Fluid Compartments
Intercellular (60% of body fluid inside cells)
Extracellular (outside cells)
Interstitial (between cells in tissue. Ex: between individual skin cells)
Intravascular (in blood and plasma)
Transcellular (Contained within epithelial lines spaces. Ex: pleural cavity)
Osmosis
Movement of WATER through a semipermeable membrane from an area of high concentration to an area of low concentration
Osmotic Pressure
Pressure needed to counter osmosis.
Colloid Osmotic Pressure
Water being pulled from the intracellular fluid into the intravascular compartment (bvs) due to a greater solute concentration in the plasma
This solute concentration exists due to plasma proteins such as albumin (greatest), globulins, and fibrinogen
Hydrostatic Pressure
"Force exerted by fluids within a compartment", in the case of intravascular fluid, is caused by heart contractions. Thus, hydrostatic pressure (bp) is greater in the arterioles than the veins, causing a pressure gradient, allowing blood to flow through the capillaries
Diffusion
Movement of IONS AND MOLECULES across a semipermeable membrane from an area of high conc to low conc.
Filtration
Movement of SOLUTES AND SOLVENTS across a semipermeable membrane AT THE CAPILLARY LEVEL OF CIRCULATION
Forces and Values of Filtration
The force behind filtration is hydrostatic pressure (the force a fluid exerts due to gravity and/or fluid movement). In the capillaries, hydrostatic pressure is generated by the pumping action of the heart.
Filtration results in 2-4L of fluid per day entering the interstitial fluid from the intravascular space.
Filtration is important for urine production
Body response to dehydration
During dehydration your blood osmolality increases. Osmoreceptors in the hypothalamus detect this change and make you thirsty. In addition to that, they tell the posterior pituitary to increase ADH which increases renal water reabsorption by increasing the permeability of the tubules and collecting duct to water. Both these actions make fluid balance normal again
Natriuretic Peptides
Natriuretic peptides are released when there’s too much blood volume (ANP released by the heart). These peptides facilitate diuresis by increasing Na+ and water loss. Natriuretic peptides also block the release of ADH and aldosterone and reduce thirst.
Aldosterone
Aldosterone is released by the adrenal cortex in response to hyperkalemia (lots of K) or hyponatremia (less Na) to counteract hypovolemia (low blood volume). Aldosterone acts on distal renal tubules to reabsorb sodium, and excrete K and H
GI Fluid Regulation w/ values
Your gastric lumen receives 1.5L of fluid from intestinal secretions, 1.5L from pancreatic juice, 0.5-1L from bile, 1.5L from gastric secretions, 1.5L from saliva swallowing, and 2L from drinking. In total it receives about 8.9L of fluid
Your intestines absorb 8.8L and therefore only 100mL is lost in feces
Diarrhea and vomiting can result in significant imbalance and loss.
Insensible Water Loss
600mL-900mL of water a day is lost from the skin and lungs, but this can change depending on fever and exercise.
Symptoms of Hypervolemia
Increased cardiac symptoms (turn up the heart)
Weight gain and edema
Average Adult I&O
Intake
Oral fluids: 1.1-1.4L
Food: 0.8-1L
Metabolism Generates: 0.3L
Output
Skin: 0.5-0.6L
Lungs: 0.4L
GI: 0.1-0.2L
Urine: 1.2-1.5L
Total intake and output should be equal at around 2.2-2.7L
What urine rate is a cause for concern?
Hourly output of <30mL/hour for 2 hours is cause for concern.
Urethra sizes
Urethra is 3-4cm in females and 18-20cm in males
Urge to void
Urge to void first felt when bladder is 250-300mL full
Strong urge at 500mL
Positive vs Negative Balances
Positive Balance: Input>Output
Negative Balance: Input<Output
Adult and Infant Urine Rates
Adults urinate approx 1.5-1.6L of urine a day. Approx every 4-5hours
Up to age 2: 2mL/kg/hour
Age 2+: 1mL/kg/hr
How does Age Influence Fluid Imbalances in the Body
Infants: Have more water and therefore have more oppurtunity for defecits
Children (2-12): Less ability to regulate imbalnces. Frequent illness can affect imbalances
Adolesence: More metabolism = greater need for hydration
Older adults: Less ability to compensate for imbalances.
Fluid volume deficit (FVD)
aka hypovolemia, condition where body losses an excessive amount of fluid
Fluid volume excess (FVE)
aka hypervolemia, condition where body contains/retains an excessive amount of fluid
How can urinary retention affect fluid imbalances in the body?
Accumulation of urine in the bladder due to the bladder's inability to empty , causing feelings of discomfort, pressure, tenderness, restlessness, and diaphoresis. Can result in UTI and UI
What are 7 types of urinary incontinences?
Transient UI= caused from factors outside of urinary system
Urge UI= Involuntary loss of urine with urgency, frequency, or nocturia
Stress UI= Involuntary loss of urine upon physical exertion
Mixed UI= Urge + Stress UI
UI assoc with chronic retention of urine = involuntary loss of urine when bladder does not completely empty with a high residual urine volume
Functional UI = loss due to inability to reach toilet
Neurogenic bladder dysfunction = lower urinary tract dysfunction, causing urge incontinence, frequency, and retention
What urine characteristics should be noted during a urinary assessment?
Color
Normal: pale straw
Amber/ Bleeding: dark red from kidney or liver dysfunction, bright red from bladder or urethra/ also influenced by food and medication
Clarity
Normal: Transparent
Cloudy+Foamy: Renal disease, bacteria
Mucous: normal w/ pts with urinary diversions, increased production= UTI
Odor
More concentrated = stronger
Incontinent = ammonia odour
Diabetes mellitus or starvation = sweet-fruity odor
Amount
(<30ml/hr for 2 hours is concerning)
How should urine collection be adjusted for pediatric patients?
- Offering water 30 minutes before collection
- Using terms that children can understand
-Use of potty chair or toilet seat instead of receptacles
-Use of clear plastic single use bags for toddlers that are not potty trained
What are the steps to using a bladder scanner
1. Identify patient and perform hand hygiene
2. Place patient supine with head slightly elevated, expose abdomen
3. Turn scanner on, clean before use
4. Palpate pubic bone, apply ultrasound gel to midline abdomen above pubic bone
5. Place scanner on gel and apply light pressure, point downward slightly toward bladder