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Evidence-based decision making (EBDM)
Making decisions grounded in the best available research, professional experience, and factors related to each patient's context, including needs and preferences
Evidence-based practice (EBP)
Application of EBDM across diverse clinical and nonclinical professions incorporates the knowledge and expertise from diverse professions (i.e., collaboration among medical, dental, and research) to provide the best quality of care to patients
Purpose of EBP
Provides care that optimizes a patient's outcomes through integration of best evidence
Need for EBP
Integrating best evidence into practice and management, being able to answer patient questions, and updating ourselves on current practices
3 major elements of EBP
clinical expertise
patient preferences
best evidence
Best available research evidence
Review of relevant, current, and high-quality clinical research that identifies best-practice treatment choices
Patient preferences or values
Consider, respect, and evaluate the patient's needs, wants, expectations, and personal context (i.e., cultural, religious, capabilities, health status, and demographics)
Clinical expertise
Enhances the ability to identify the patient's health, risks, needs, and potential for various interventions
Skills for EBP
Understand EBDH practice, follow a systematic approach, read and understand research, be computer literate, embrace self-directed learning, and be a resource for others
Systematic approach
Step-by-step approach by asking questions related to clinical practice to ensure success
Read and understand research
Recognize valid and reliable information. Determine strengths and limitations of publications, journal articles, research methods, study designs, and biostatistics
Be computer literate
Develop the skill to search for scientific literature effectively and efficiently. Practice critical thinking skills to evaluate information found online
Embrace self-directed learning
Develop a plan for continuing education and reading of professional literature that will help to maintain current knowledge
Be a resource for others
Help patients and colleagues identify and value scientific support for clinical recommendations
Systematic steps
Assess
Ask
Acquire
Appraise
Apply
Audit
Assess: determine clinical issue
Completes an assessment of the patient or population.
Next step is to identify what the clinical issue or problem is for the patient or population.
Purpose is to clarify the clinical issue or problem
Ask: develop a research question
Asking the right research question is fundamental and critical to the EBP model.
Research questions should be focused, neither too broad nor too narrow.
A researchable question includes four parts, referred to as PICO.
Good research questions should also adhere to the FINER criteria.
PICO
Patient problem or population
Intervention
Comparison
Outcome
Patient problem or population
Most important issues the patient or population of interest is facing
Intervention
Plan to address the patient's or population of interest's issues
Comparison
What is the main alternative being suggested? Compare the alternative with the standard intervention for the patient or population of interest
Outcome
What is the desired measurable outcome, accomplishment, improvement, or effect from the proposed intervention on the patient or the population of interest?
FINER criteria
Feasibility
Interesting
Novel
Ethical
Relevant
Acquire: search for scientific evidence
Select appropriate resources and conduct a thorough literature review.
Scientific articles are available through library databases and by using appropriate search engines. Focus the literature review toward current and higher levels of evidence publications
Types of information sources
Primary, secondary, tertiary
Primary sources
Original accounts of events and/or publications, they provide unfiltered access to an original record of thought and/or achievement during a specific period in history
Examples of primary sources
Narratives, speeches, autobiographies, government documents, patents, raw data sets, and experimental research reports
Secondary sources
Published materials that synthesize and/or analyze original sources
Examples of secondary sources
Biographies, literature reviews, and non-experimental scholarly articles
Tertiary sources
Published materials that provide overviews of particular topics with information gathered from multiple sources
Examples of tertiary sources
Encyclopedias, textbooks, and websites
Questions when considering validity of publication
Who is sponsoring?
Is there an editorial review board?
Are the journal articles peer-reviewed?
What are the credentials of the contributors?
Are there advertisements? How many?
Are there good-quality production standards?
Textbooks
Generally accepted as credible basic-level resources.
Drawn-out publication processes can make textbooks become outdated quickly
Commercial-based journals/magazines
Often free and based on product and/or service sponsorships.
Potentially written by in-house staff members without professional credentials.
Some articles summarize recent research that may contain selective reference citations, but not include all available scientific evidence
Professional journals
Produced by professional organizations. Membership dues payment is required, or receiving publications is a benefit of being a member.
Part or all of the publication is devoted to scientific studies. Most contain articles with supporting reference citations
Peer-reviewed (refereed) publications
Subject matter experts (SMEs) critically examine all components of submitted manuscripts before recommending for or against publication.
Contributing author(s) must revise the manuscript and address all significant concerns or answer questions expressed by the reviewing SMEs before receiving approval for publication.
This helps assure the validity, reliability, and objectivity of published journal articles.
Peer-reviewed journals usually list all review board members and their respective credentials in each issue of the journal
Online information
American adults are increasingly using online resources to diagnose either themselves or others, which can lead to newspaper and magazine articles or websites that may not provide science-based and/or research-supported information.
Search engines cannot assure the validity, accuracy, and objectivity of information and display fractions of all available resources on a specific topic.
High credibility
Governmental sources (.gov) and educational sources (.edu)
Moderate credibility
Organizational sources (.org) and institutional sources (.net)
Lowest credibility
Commercial sources (.com)
CRAP test
Currency
Reliability
Authority
Purpose
Currency
Consider when the source was published and if the information is still current or relevant today (sites with outdated information should be avoided)
Reliability
Consider credibility and applicability of the information. Reliable information will come from websites that are peer-reviewed, published by dependable organizations, and provide references
Authority
Consider the reputation of the author. Authors of an information source, whether individuals or organizations, should hold appropriate academic and professional credentials
Purpose
Consider the intent of the website. Sources may have the intent to inform, educate, entertain, persuade, or provide satirical information
Some health-related information from governmental agencies & nongovernmental associations
HealthFinder
MedlinePlus
Medical Library Association
Accrediting organizations provide certification w/ objective health information
Health on the Net Foundation
URAC Health Website Accreditation Program
MEDLINE database
U.S. National Library of Medicine's (NLM) main scientific database
-Provides access to articles from more than 5,600 scientific journals, including PubMed & Cochrane Collaboration database.
Cochrane Collaboration Database
Global, independent, network working to promote access to credible and unbiased health information for practitioners and patients.
Appraise: clinically evaluate evidence
Evaluate evidence based on currency, validity, & clinical value
Descriptive statistics
Numerical data used to measure and describe characteristics of groups. Includes measures of central tendency and measures of variation
Inferential statistics
Numerical data that allows one to generalize
- infer from sample data the probability of something being true of a population
Statistical significance
Likelihood that a relationship between two or more variables is due to something other than chance
Clinical significance
Practical relevance & importance among multiple therapies. It focuses on whether the significant probability of a particular therapy has a noticeable effect on a patient or population
Apply: Integrate and apply evidence
Integrate and apply evidence with clinical expertise and the patient's preferences.
Consider the circumstances and clinician's ability to help obtain potential results.
Document interventions in the patient's chart as part of clinical progress notes
Audit: Evaluate outcomes
Determine whether:
Application of EBP model successfully helped the patient.
There is a need for additional research strategies and information, or modification in the original outcome goal.
Research designs
Qualititative, quantitative, and mixed-methods research
Qualitative research
Data are collected and reported through participant observations, interviews, open-ended questions, field notations, and narrative reflections
Quantitative research
Sample sizes are typically larger and randomly selected.
Data are collected and reported as quantifiable numbers and/or statistics
Mixed-methods research
Purpose is to combine the best of both qualitative and quantitative research approaches.
Sample sizes and random selection may vary.
Data are collected and reported as both qualitative insight and quantitative analysis
Research types
Descriptive, correlational, quasi-experimental, experimental, review
Descriptive research
Observes behavior to describe that behavior objectively and systematically (case studies, natural observations)
Correlational research
Identifies whether an association or relationship between two factors exists (ex: cohort studies, population surveys)
Quasi-experimental research
Researcher cannot assign participants to conditions or manipulate the independent variable (ex: correlational studies)
Experimental research
Designed to discover causal relationships between various factors (ex: randomized controlled trials)
Review research
-synthesizes relevant information on a particular research topic
-intended to summarize and evaluate scientific literature (ex: meta-analysis)
Levels of evidence
Hierarchal framework to determine the strength of an article
Levels of scientific evidence pyramid
Meta anaylsis
Systematic reviews, Randomized controlled trials
Cohort Studies
Case Control studies
Case Studies
Animal and Lab Preclinical Trials
Meta-analysis
A "study of studies" that combines the findings of multiple studies to conclude (Platinum)
Systematic reviews
Rigorous and systematic synthesis of research findings about a clinical problem (Diamond)
Randomized controlled clinical trials
Carefully planned experiments introduce a treatment or exposure to study its effect on real patients. They include methodologies that reduce the potential for bias (randomization and blinding) allowing for comparison between intervention groups and control (no intervention) groups (Gold)
Cohort studies
Follow the same subject group from the present to a specified point in the future. This research design compares a group with exposure against a group without an exposure
Case control studies
Explore into the past to identify common factors between two groups, one with an exposure and the other without an exposure
Case studies
In-depth analyses and descriptions of a series of cases of an unusual or complex condition
Case reports
Professional articles describing the diagnostic, preventive, and therapeutic services rendered to one patient with an unusual or complex condition
Narrative reviews
Basic, descriptive-based literature reviews that synthesize information on a particular topic without a methodological approach
Editorials
Articles in a newspaper or magazine that express the opinion of its editor or publisher
In vitro trials
Experimental testing completed through test tubes and other similar equipment in the laboratory
In vivo trials
Experimental testing completed through test tubes and other similar equipment in the laboratory
Prospective study
Observes for outcomes, such as the development of a disease, between the present and some defined point in the future
Retrospective study
Observes established outcomes, such as an existing disease, but examines by exploring potential risk or protective factors within a specified timeframe in the past
Cross-sectional study
Examines several different samples at one specified point in time (i.e., provide a snapshot)
Longitudinal study
Examines the same sample over an extended period (i.e., several points in time). Results from longitudinal studies can indicate potential causality claims
Human subjects dental hygiene studies
Studies on extracted teeth, discarded gingiva, other tissues, saliva, blood, urine, etc.
Ethical research standards
Self-determination.
Privacy
Anonymity and confidentiality
Fair treatment
Protection from discomfort and harm
Understanding the risks and benefits of participating in the study
Informed consent
Institutional Review Board (IRB)
Committee of administrators, scientists, and community members that reviews proposals for research involving human participants
SOAP
Subjective
Objective
Assessment
Plan
Example of subjective
Chief complaint, symptoms
Example of objective
Clinical signs, patient examined, and some diagnoses
Example of assessment
Reviewing scientific literature and applying
Example of plan
Verbal and written instructions to the patient on steps to take to improve or maintain their condition