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Technological Techniques
Advanced imaging methods used to study brain structure (anatomy) and function (activity). They allow psychologists to correlate observed brain activity/structure with specific behaviors or cognitive processes
MRI (Magnetic Resonance Imaging)
Uses powerful magnetic fields to create detailed structural images of brain tissue. Helps identify tumors, lesions, or developmental abnormalities.
fMRI (functional MRI)
Measures blood oxygen levels (blood flow changes) to show which brain areas are active during specific tasks (e.g., memory recall, language). Has high spatial resolution (precision in location).
Historical Techniques
Earlier methods like post-mortem examinations (e.g., Broca ), lesion studies (e.g., Phineas Gage, H.M. ), and EEG(measuring electrical activity ). These provide pre-fMRI context for studying the brain
Localization of Function
The idea that specific brain regions control particular functions. It provides a fundamental framework in neuroscience (e.g., motor cortex controls movement, hippocampus for memory).
Supporting Evidence
Examples of specialization: Broca's area for speech production ; the visual cortex for sight ; and how strokes/disease affect specific regions (e.g., Alzheimer's initially affecting memory regions)
Limitations/Modern View
Strict localization is oversimplified. Most complex functions (like language) emerge from networks spanning multiple brain regions. The brain also shows plasticity (functions can shift after injury)
Functional Distribution
A concept challenging strict localization: A single function (e.g., language) often depends on multiple brain regionsworking together
Neural Networks
Circuits built from individual neurons that communicate through synapses. Activity creates cascading patterns that coordinate complex functions across distributed brain areas. Modern view emphasizes connectivity
PFC-Amygdala Circuit
An example of a network, often called the emotion regulation network or fear circuit. It involves bidirectional communication.
Function of the Circuit
The Prefrontal Cortex (PFC) sends inhibitory signals to the amygdala to regulate and calm emotional responses (emotional regulation). It also helps with fear extinction and decision-making under emotional conditions.
Clinical Relevance
Disrupted PFC-amygdala connectivity is implicated in mental disorders like anxiety, PTSD, and depression
Hormones
Chemical messengers produced by endocrine glands that travel through the bloodstream. They create widespread effects on brain function and behavior, unlike neurotransmitters that work at specific synapses.
Cortisol
primary stress hormone. Prolonged exposure (chronic stress) damages the body. Moderate levels enhance memory, but high levels impair it (e.g., during extreme stress).
Other Key Hormones
Testosterone influences aggression and competition. Estrogen affects mood and cognition. Oxytocin promotes social bonding and trust.
Berthold (1849)
Historical study showing that chemical signals (later identified as hormones from the testes) affected behavior (aggressiveness) in roosters