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What does HIV target
CD4 white blood cells
Acute HIV infection s/s
Fever
Night sweats
Chills
Headache
Muscle ache
Sore throat
Rash
What marks is staged as acute HIV
Rapid rise in the HIV viral load
Decreased CD4+ cells
Increased CD8 cells
What is AIDS characterized with
Life-threatening opportunistic infections
What stage is the end stage of HIV
AIDS
Without treatment of AIDS, how long until death
Death occurs within 5 year
Stage 1 HIV CD4 t-lymphocyte count
500 cells
Stage 1 HIV CD4 t-lymphocytes % of total lymphocytes
29% or more
Stage 2 HIV CD4 t-lymphocyte count
200 - 499 cells
Stage 2 HIV CD4 t-lymphocyte % of total lymphocytes
14% - 28%
Stage 3 (AIDS) CD4 lymphocyte count
Less than 200 cells
Stage 3 (AIDS) CD4 t-lymphocytes % of total lymphocytes
Less than 14%
health promotion of HIV
Teach pt how to virus is transmitted and ways to prevent it (condom, abstinence, avoid sharing needles)
Maintain vaccines (yearly influenza, pneumococcal polysaccharide vaccine)
Older female pt experience
Vaginal wall dryness and thinning increasing the risk of HIV
Lab test of HIV
CBC (abnormal anemia)
Platelets ( less than 150,000
What age is recommended to get tested for HIV
Between 13 andd 64
What do fusion inhibitors meds do
Enfuvirtide blocks the fusion of HIV with the host cell
What do entry inhibitors meds do
Maraviroc block CCR5 receptor on the CD4 T cell to prevent progression of the infection
What does nucleoside reverse transcriptase inhibitors meds do
Zidovudine interferes with the virus ability to convert RNA into DNA
What do protease inhibitors meds do
-vir prefix
They inhibit an enzyme needed for the virus to replicate
What do integrate inhibitor meds do
Raltegravir and dolutegravir inhibit viral replication by stopping HIv enzyme interface from inserting into the host cell
What do antineoplastic meds do
Interlocking is an immunostimulant that enhances the immune response and reduce cancer cell production
What is the ratio of normal CD4 to CD8
2:1
What does a CD4 to CD8 ratio of 1 indicate
Anything less than 1 indicates more severe disease manifestation
What are alternative therapies for HIV
Vitamins
Herbal products
Shake cartilage
They help alleviate manifestations of HIV
What should pt with HIV avoid
Raw food (fruits and veggies)
Crowded places
Countries with poor sanitization
Cleaning litter box (reduce the risk of toxoplasmosis)
Undercook food
What to do for pt with wasting syndrome
Rinse mouth with saline or sodium chloride
Maintains nutrition orally or TPN
Provide between meal supplements and snack
Decrease fat content
Serve at least 6 small feedings with high protein value