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Denominational switching:  People who move from one sect of Christianity to another  “spiritual supermarket syndrome” “pew hoppers” or “switchers” -> name calling - Growing trend in western world towards denominational switching - People no longer making lifelong commitments to one church but more likely to swap based on where they feel comfortable and are catered for o Contrast to historic patterns where individuals and families traditionally remained affiliated with one denomination for generations - Reflection of modern consumer society - Reason for increase: mobility o Growth in car ownership since 1945 makes it easier to travel to favoured church rather than local parish church - Main losers of switching are older, mainstream, traditional denominations o Lutherans, uniting church, presbyterian, Anglicans NOTE: number of Catholics switching is very low - Pentecostal churches -> reason for switch is charismatic leaders in Pentecostal churches preach with great authority and services include rock bands Interdenominational switching: - Pentecostal churches have been greatest beneficiaries of “switchers” due to: o Aggressive evgelization o Focus on personal salvation o “up-tempo” gospel services o Attractive services to under 40’s in particular o Less focus on social, ethical or moral issues o Personal following of preachers - Revolving door syndrome -> Pentecostal churches loose membership as fast as they are gained Who switches and why? - Under 40s less likely to view lifetime loyalty to particular type of church as important (15%), compared to 60+ (38%) - People with active Christian faiths more likely to switch to seek stronger Christian community and exclusively provided - Family breakdown was another factor -> children of divorce 64% more likely to cease identifying with family faith than those of non-divorced parents o Catholics 1.7x more likely to switch to a moderate protestant (methodist) denomination and 2.6x more likely to switch to conservative protestant (Baptist, evangelical) denomination Denominational dissatisfaction: - Most people who stop attending church regularly don’t stop attending completely -> they continue to be searchers - Found services to be boring - Looking for openness to different views of religious matters and broad approach to worship catering for different spiritualities - Former adherents baulk at ‘hard-line’ moral and ethical stances on contentious issues e.g. abortion Rise of new age religions:  Extremely diverse in nature with focus on fostering individual fulfillment in regard to happiness, health and meaning in life (individualism)  New age religions can be followed instead of traditional religious practices or can be practised alongside traditional religions - Popular bc traditional religions fail to resonate with modern people - New age religions have been growing since 1970s and now include: o Feng shui o Tarot cards o Astrology o Meditation o Scientology o Spiritualism o Philosophy - New age religions tend to reject monotheism, but may except polytheism, worship of nature (pantheism), goddesses, or monism (belief that everything is one) - New age religions often adopt elements of eastern religions, and may incorporate elements of numerology, astrology, yoga, tai chi, paganism and feng shui - Part of appeal is they provide freedom for adherents to pick and choose what they believe fulfills them in spiritual manner - From 1996-2001 140% growth in new age religions in census Reasons for growth include: - Disillusionment with traditional religion and traditional worship - Frustration with slowness of change - Desire for personal fulfillment - Desire to find new ways of seeking inner peace and health - Response to globalisation and de-centring of western ‘truths’ - Ease of travel - Lessening of commitment to traditional structures such as churches Links to religious traditions: - Trend towards new age religions introduced number of Hindu concepts into language and practice of many people who may not necessarily consider themselves religious - Practices include meditation, yoga and concepts such as reincarnation and karma Secularism:  Movement/concept which rejects religious belief or adherence  Belief that religion should not interfere with or be integrated into the public affairs of a society - Significant number of Australians are not religious, and number is still growing - Trend could be result of greater levels of technological and scientific knowledge + perseverance of many religions in antiquated and conservative attitudes - Some perceive to be hypocrisy that religions still try hold themselves to be moral authorities Promotes idea that society would be better off by not being controlled by religion for reasons including: - Pluralism: diversity of beliefs and cultures - Individualism, materialism and scepticism towards supernatural as result of scientific progress - Disillusionment with traditional religions Reasons for reduced membership of religious or attendance at church are varied but include: - Church practices that are boring or unfulfilling - Disagreement with church theology or stance on moral and social issues - Alternative practices that meet same needs as church e.g. social groups - No time for church - Personal dislike of religion - Technology and scientific advances that conflict with church Effects of secularism: - Loss of religious value - Lack of religious church practice e.g. civil marriages, non-religious funerals - Seeking alternative “religions” or “forms of spirituality” - Greater trust in science and belief in supernatural is contradictory to what many believe to be empirically true - Rise of new age religions which focus on personal satisfaction, self-help groups, happiness, mind and spirit exhibitions - Until 1973, australians only had two options for where + how they could get married (church or registry office) o Today 80%+ wedding ceremonies now performed by civil celebrants (up from 50% in 2021) Ecumenical movements within Christianity: - Increasingly secularised society - Involvement in issues of peace and social justice to renew relevance - Multifaith society requires ongoing dialogue with those who have different beliefs and practices - In australia today, relationships between Christian churches (ecumenism) and relations between various religious traditions (interfaith dialogue) are characterised by mutual tolerance and respect Ecumenism: - Movement among Christian churches to promote the restoration of unity among all Christians -> “collective movement” - Aims to bring branches (denominations) of church back to single community of faith or ‘body of Christ’ Sectarianism = Conflict between two groups of a particular faith - Sectarianism found in other countries is less vigorous in Australia Ecumenism is recent philosophical approach in life of church and australians have supported ecumenical ideas - Uniting Church in Australia - National Council of Churches - NSW Ecumenical Council Uniting church: - Formed 22nd June 1977 - Result of union of three individual churches o Congregational union of australia o Methodist church of australia o Presbyterian church of australia - “most significant ecumenical event in Australia’s history” (Francis Rush – Catholic Archbishop of Brisbane) - Particularly known for social justice approach and support for marginalised sections of society National council of churches in Australia: - Umbrella organisation bringing many of Australia’s churches together - Happens in both practical and organisational cooperation and discussion on faith-bade issues - Officially became NCCA in 1994 with inclusion of Catholic Church NSW Ecumenical Council: - Founded in 1982 - Encourages social justice and operates on an ecumenical level to achieve this - Central bond is that they’re all followers of Christ, so there’s unity amongst adherents o Rather than competing against each other, they come together in accordance with sense of Christian duty - Gives churches shared voice when following religious beliefs and undertakings - Involved in community projects such as helping settle refugees and providing accommodation to poor - Christmas Bowl initiative -> local church projects that aid people with needs - Local + international initiatives allow churches to have more significant impact o If they were separated there wouldn’t be as much impact - Domestic violence project -> raises awareness about how to respond to domestic violence and how to support survivors - Commission on middle east -> international initiative where member churches come together to advocate for Christians, minority groups and asylum seekers in Middle East Interfaith Dialogue:  Move to greater cooperation and harmony between people of different religious traditions  Involves positive communication and cooperation resulting from discussion between different faiths  Often involves discussing matters of societal + faith concern  Often led by ecumenical groups within a religion Example: NCCA (est. 1994) has ongoing dialogue with Australian Federation of Islamic Councils and Executive Council of Australian Jewry - Important to include all sectors of each religion “No World Peace without peace between the religions” Importance of interfaith dialogue: - Topics impact everyday Australian life - Discussing impacts of belief or behaviour reduces tension and misunderstanding - Some topics of community concern are important not only to religious community but also wider secular society of Australia and the world * Building understanding, goodwill and sense of community * Consider issues as a whole community * Encourages and allows individuals to learn about each other and different faiths * Encourages activities and projects of commonality within and between faiths * Importance for young people -> idealism and enthusiasm of youth Recent interfaith initiatives: 1991: Australian Council of Christians and Jews - Goal is to recognise common heritage and promote understanding 2004: The Columban Centre for Christian-Muslim Dialogue - Located in Turramurra -> focuses on dialogue between Christians and Muslims particularly among women 2007: one of largest groups to attend the Dalai Lama’s visit to Canberra was the Association for Studies of Religion Presently: as recognised by Cambridge text, the provision of Studies of Religion in the NSW HSC is, in itself, an example of interfaith dialogue 2023: last world parliament of religions in Chicago (where all faiths come together) Atomi Notes (need to fix): Current religious landscape in Australia: Christianity as major religious tradition: Immigration: - Most immigration from Britain 1945: migration brought Christianity into Australia (mainly Catholicism) - Was mainly impacted by new variety of ethnic backgrounds 1945-60: jews arrive from Europe 1960: drastic moves to restrict racial diversity in Australia 1973: white australia policy abandoned - Planned program for asian immigration 1975: asian immigration dramatically increased following Vietnam War - Australia accepted 120,000 refugees from Indochina Post 1975: spike in total Muslim population in Australia Denominational switching: People moving between sects of Christianity - Only comes from people who attend church - Source of information is from National Church Life Survey o Only 8% of people attend church - Christianity not further defined was biggest growing Christian response in 2016+2021 Rise of new age religions: Alternative spiritualities that aim to foster personal happiness, health and meaning in life - Popular bc traditional religions fail to resonate with modern people Mind, body, spirit festival -> Secularism: Belief religion should not interfere with or be integrated into public affairs of society - Promotes ideas that society would be better off by not being controlled by religion o Pluralism: diversity of beliefs and cultures o Individualism, materialism and scepticism towards supernatural as result of scientific progression o Disillusionment Ecumenism: • Impact of movements within australia (syllabus dot point) - Movement for dialogue and mutual understanding between Christian Churches o Response to immigration post 1945 National council of churches australia (NCCA): - Formed 1944 and consists of 18 member Churches across Australia - Runs programs o Act for peace o Safe church awareness o Australian churches refugee taskforce  Aims to apply Christian moral voice to suffering of refugees and asylum seekers  Gives combined Christian churches political voice in scheme of australia’s secularism  Combined power of churches means they have bigger impact on this social issue o Christmas bowl mission  Sends aid assistance to countries throughout Africa, asia, middle east and pacific NSW ecumenical council: - Formed 1982 with 18 member churches - Runs many initiatives o Domestic violence project  Allows church to have greater impact together rather than being separate o Commission on middle east  International initiative where member churches come together to advocate Christians, minority groups and asylum seekers in middle east How to answer a 5 marker: - Combine content with census data dot point - Always refer to stimulus explicitly o Look for dates, change in denomination, changed services offered 1) Intro -> Identify changes in australia’s religious landscape a. Denominational switching b. Immigration c. Secularisation 2) Explanation -> go through each change, referencing the syllabus Extra class notes: - Salvation army is a Christian denomination Examine the relationship between aboriginal spiritualities and religious traditions in the process of Reconciliation Reconciliation: - Process which changes relationship between individuals or groups for the better - Mainly used in Australia to describe way of improving relationships between Indigenous and non-Indigenous Australians - Involves acknowledgement of injustices of past and dispossession, willingness + commitment to rectify these wrongs where possible, to improve the position of Aboriginal peoples in the future Key events: 1991 -> Land rights movement Dec 10, 1992 -> Redfern speech (PM Paul Keating) May 28, 2000 -> Sorry Day Sydney Harbour Bridge walk - More than 250 000 people walked across bridge to press Federal Government to apologise Feb 13, 2008 -> Federal Government apology - PM Rudd apologised on behalf of the Parliament and Government of Australia for past injustices - Stated apology was to “Remove a stain from the soul of Australia” and “It was time for all Australians, to come together, truly reconcile and together build a truly great nation” Kanyani video notes: - Country is family for Indigenous people o They live in + amongst nature e.g. walking around in natural state, no houses (huts) and sleep under the stars on the earth o All animals living with them are family - Born from Mother Earth and supported by her o “she looks after us with meat, bush tucker as well as water” - Trained to look after ceremonies, land and each other -> main importance - Never take more than you need and don’t destroy to the level where it cannot produce again o Duty to the land and caring for it - Each person is given totem animals o Not allowed to ever kill that animal - Spirit, psyche, mental, physical are all connected with every form - Oneness + completeness of oneness for everything - Every inch of land + waterways is sacred Aboriginal Spirituality Dreaming: - Definition: The Dreaming is infinite and links the past with the present to determine the future. It encapsulates the stories of creation and life in Aboriginal culture. - The Dreaming is the central and deepest reality of the Aboriginal world. - It is the spiritual dimension of reality that has existed from the beginning and continues to be present in all aspects of life. o The Dreaming is inextricably linked with the land Characteristics and features of the Dreaming - Dreaming is experiences through songs, stories, rituals and symbols. - Dreaming establishes the lore linking the relationship between Aboriginal people, the land, and all things associated with Aboriginal life. - This is evident through: o Kinship structures of society o Rules and obligations for social behaviours o Ceremonies performed to maintain the life of the land. - Quote: “The Dreaming refers to all that is known and all that is understood. It is the way Aboriginal people explain life and how their world came to being.” – 2024 Aboriginal Art and Culture, Alice Springs Australia. Kinship: - Kinship systems define where a person fits into the community, binding people together in relationships of sharing and obligation to one another and the land. - Connection to Dreaming: o Kinship binds culture, Country, family and community together it is a way of being. o Kinship systems assign the responsibility to transmit the knowledge of the Dreaming from Elders to the younger generation - Quote: “All people with the same skin grouping as my mother’s… They have the right, the same as my mother, to watch over me, to control what I’m doing, to make sure I do the right thing. It’s an extended family thing… It’s a wonderful secure system.” – Wadjularbinna Doomadgee Gungalidda leader, Gulf of Carpentaria, 1996 Ceremonial life: - The spirituality of Aboriginal people comes from their belief and understanding of the Dreaming, and how this has been taught to them throughout generations. - Ceremonial life is an essential expression of the Dreaming, connecting individuals with their ancestors, the land, and each other. Connections between ceremonial life and the Dreaming (STAR) - Stories from the Dreaming describe Aboriginal law and lifestyle, teaching about the way of life - Totems represent the individual as they existed in the Dreaming and carry ceremonial responsibilities (the embodiment of each individual in their primordial state) - Art communicated the Dreaming and the multiple layers of meaning - Rituals form the Dreaming and is a way to relive activities of ancestor spirits Obligations to the land and people - In Aboriginal society, people do not own the land it is a part of them, and it is part of their duty to respect and look after Mother Earth - Land has significance for all First Nations people as the sacred places provide a sense of identity and connection - Relationships within kinship groups connect people to places and define their obligations to each other - The land is an important aspect of Dreaming stories, particularly those associated with the time of Creation. - Custodianship o Custodianship of the land is a sacred duty bestowed upon Aboriginal people by the Dreaming - Sacred Sites o Specific locations are considered sacred because of the physical manifestations of the Dreaming. o These sites require special care and are often the focus of rituals - Sustainability Practices o Dreaming stories often includes teachings on how to care for the land o Practices such as controlled burning and seasonal hunting aim to ensure the land remains healthy for future generations. Aboriginal people believe they are related to, and custodians of natural world - This relationship provides advantages of survival and life and also imposes responsibilities of preservation and education In the land, aboriginal people see evidence of Dreaming and creation Dreaming stories which describe ancestors or Creation are set in land and describe actual land where people live Aboriginal people believe the Dreaming ancestor became the land Aboriginal people describe themselves as being descendants of particular ancestral beings Therefore have continuous and living relationship with features of the land Inseparable from the land and so believe if they are removed from the land then they will die (spiritually not literally) Ceremonial life: - By performing ceremonies, the Dreaming and its giving power loves on through human beings and animals - Ceremonies highlight the connection to the Dreaming, the importance of land, and relationships between people - Examples: initiation ceremony, men’s law and women’s law, funeral ceremonies, celebration ceremonies Purpose of aboriginal ceremonies: Rites of passage Inform all of the new status of the individual e.g. initiations and funerals Information Transfer from elder to younger generation Changes the social custodians of history Personal Support personal friendships Support personal or group activities e.g. intertribal or totemic group trade or cultural meetings Spiritual Maintain the link and connect people with the spiritual world or the Dreaming Types of aboriginal ceremonies: Ceremony Description Initiation ceremony Teaches young people bout the law and the spiritual beliefs Allows them to take their place as an elder in the community Men’s law and women’s law Each tribe has gender-specific roles and ceremonies Respect for individuals and the whole family is shown by accepting men’s and women’s law Funeral ceremonies Rite of passage from the living world to the spirit world Activities can include sprinkling of water, smoking of (bark) coffin, flowers, memory celebration Restriction of naming deceased person Celebration ceremonies Celebrate the telling of a Dreaming story Dancing and artwork happy and joyous The cause of continuation of life itself Ceremonies have changed over recent time bc of the impact of external religious beliefs (mainly Christian) and other social factors which have removed young people from their land and tribal support In some cases aboriginal spiritual beliefs have combined with Christianity in a form of syncretism (syncretism = combing of; coming together of …) Removal from land, kinship, and community has meant important ceremonial connections are becoming less effective Corroboree indicates a ceremony driven by settlers’ vernacular however they took that from one of the aboriginal torres strait islander peoples words for rituals which is ?keraberre? These ceremonies often centre on retelling of Dreaming stories -> singing, dancing, music and mime -> often body of actor is decorated to represent a spirit he/she is portraying Activities for rite of passage -> testing of strength, revelation of knowledge, the removal of the child from the biological mother, seclusion (learn to live of the land), giving of new name/sacred object Burial ceremonies -> death is time where spirit leaves body and returns to ancestor spirits -> certain ceremonies are used to encourage spirit on its journey
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📚 8.1 How Companies Find and Develop New Product Ideas Sources of New Product Ideas: Internal Sources: R&D, employee suggestions, brainstorming sessions. External Sources: Customers: Surveys, feedback, complaints, and suggestions. Competitors: Analyzing competitors' products to identify gaps or improve upon existing ideas. Distributors/Suppliers: Insights into market trends and supply chain opportunities. Crowdsourcing: Engaging the public for innovative ideas. Developing New Ideas: Idea Screening: Filter out bad ideas early to focus on the most promising ones. Concept Development and Testing: Test concepts with target customers to gauge their response. 🔄 8.2 Steps in the New Product Development Process Idea Generation: Brainstorming ideas from internal and external sources. Idea Screening: Evaluate ideas to eliminate unfeasible ones. Concept Development and Testing: Develop product concepts and test them with target audiences. Marketing Strategy Development: Create a marketing plan for pricing, distribution, and promotion. Business Analysis: Assess the financial feasibility (cost, demand, profitability). Product Development: Build and test prototypes or minimum viable products (MVPs). Test Marketing: Introduce the product to a limited market to assess performance. Commercialization: Full-scale launch of the product. Major Considerations: Customer-Centricity: Focus on customer needs and feedback. Speed to Market: Minimize delays in the development cycle. Risk Management: Anticipate and address potential product risks. 📈 8.3 Stages of the Product Life Cycle (PLC) & Changing Marketing Strategies Introduction: High marketing costs, slow sales growth, and minimal profit. Strategy: Build awareness, offer promotions, and use selective distribution. Growth: Rapid sales increase, rising profits, and market expansion. Strategy: Improve product quality, expand distribution, and adjust pricing to maximize market share. Maturity: Sales peak, profits stabilize or decline due to competition. Strategy: Modify the product, look for new market segments, and focus on differentiation. Decline: Sales drop, profits decrease, and the market shrinks. Strategy: Harvest (reduce costs and maximize remaining profit) or divest (discontinue the product). 🌱 8.4 Additional Product Issues ✅ Socially Responsible Product Decisions: Product Safety: Ensuring products meet safety standards. Environmental Impact: Minimize environmental harm (sustainable sourcing and packaging). Ethical Marketing: Honest communication and avoiding deceptive advertising. 🌍 International Product and Services Marketing: Adaptation vs. Standardization: Adaptation: Modify the product to fit local preferences or legal requirements. Standardization: Keep the same product globally to maintain consistency. Cultural Sensitivity: Tailoring messaging and branding to align with cultural values. Regulatory Compliance: Meeting the local standards and regulations in different countries
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enska orðalistar
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biology 2.1Unit 2.1: Mitosis and Meiosis Introduction By the end of this section, you should be able to: Define a chromosome. Define DNA as the genetic material. Define genes. Describe the structure of chromosomes. Describe the components of DNA. Define mitosis and describe its stages. Define meiosis and describe its stages. Relate the events of meiosis to the formation of sex cells. Compare mitosis and meiosis. Chromosomes, Genes, and DNA Almost all the cells of your body—except for mature red blood cells—contain a nucleus, which acts as the control center of the cell. The nucleus holds all the information needed to make a new cell and, ultimately, a new individual. Inside the nucleus are chromosomes, thread-like structures that store genetic information passed from parents to offspring. Chromosomes are made up of DNA (deoxyribonucleic acid), a molecule that carries the instructions needed to make all the proteins in your body. Many of these proteins are enzymes, which control the production of other chemicals and affect everything about how your body functions. Each species has a specific number of chromosomes: Humans have 46 chromosomes (23 pairs). Tomatoes have 24 chromosomes (12 pairs). Elephants have 56 chromosomes (28 pairs). Half of your chromosomes come from your mother, and the other half from your father. These chromosomes are arranged in homologous pairs, meaning they contain matching sets of genes. A karyotype is a special photograph that arranges chromosomes into their pairs. In humans, 22 pairs of chromosomes are called autosomes, which control most body functions. The 23rd pair is the sex chromosomes, which determine whether you are male or female: Females have two X chromosomes (XX). Males have one X and one Y chromosome (XY). DNA Structure DNA is a long, twisted molecule shaped like a double helix (a spiraled ladder). Each strand of DNA is made up of smaller molecules called nucleotides, which consist of: A phosphate group A sugar (deoxyribose) A nitrogen base The four nitrogen bases in DNA are: Adenine (A) → Always pairs with Thymine (T) Cytosine (C) → Always pairs with Guanine (G) Genes are small segments of DNA that carry instructions for making proteins. The sequence of these bases acts like a biological code, directing the cell to create specific proteins. In 1953, James Watson and Francis Crick, using data from Rosalind Franklin’s X-ray photographs, discovered the double-helix structure of DNA. Their discovery led to a huge increase in genetic research, including the Human Genome Project, which mapped all human genes. Mitosis (Cell Division for Growth and Repair) All body cells (somatic cells) divide using mitosis, a type of cell division that creates two identical daughter cells. Mitosis is essential for: Growth (producing new cells). Tissue repair (replacing damaged or old cells). Asexual reproduction (producing offspring with identical DNA). Stages of Mitosis Interphase The cell prepares for division by copying its DNA. Chromosomes are not visible under a microscope. Prophase Chromosomes condense and become visible. The nuclear membrane breaks down. Metaphase Chromosomes line up in the center of the cell. Spindle fibers attach to each chromosome. Anaphase The spindle fibers pull the sister chromatids apart to opposite ends of the cell. Telophase A new nuclear membrane forms around each set of chromosomes. The cell is almost ready to split. Cytokinesis The cytoplasm divides, forming two identical daughter cells. Mitosis is constantly occurring in areas like your skin and bone marrow, where new cells are needed regularly. Meiosis (Cell Division for Reproduction) Unlike mitosis, meiosis occurs only in the reproductive organs (testes in males, ovaries in females) and produces gametes (sperm and egg cells). Gametes have half the number of chromosomes (haploid, n=23) so that when fertilization occurs, the new cell has the correct chromosome number (diploid, 2n=46). Stages of Meiosis Meiosis consists of two rounds of cell division, resulting in four non-identical cells. Meiosis I: Prophase I – Chromosomes pair up and exchange genetic material (crossing over). Metaphase I – Chromosome pairs line up in the center of the cell. Anaphase I – Chromosome pairs separate and move to opposite ends of the cell. Telophase I & Cytokinesis – The cell splits into two haploid daughter cells. Meiosis II (similar to mitosis): 5. Prophase II – Chromosomes condense again. 6. Metaphase II – Chromosomes line up in the center. 7. Anaphase II – Sister chromatids separate and move to opposite sides. 8. Telophase II & Cytokinesis – Four unique haploid gametes are formed. Each gamete is genetically different due to crossing over and random chromosome distribution. Mitosis vs. Meiosis: Key Differences Importance of Mitosis and Meiosis Mitosis ensures that cells grow, repair damage, and replace old cells. Meiosis allows genetic diversity, which is essential for evolution and survival. Summary Chromosomes carry genetic information in the form of DNA. Genes are sections of DNA that code for proteins. Mitosis produces two identical daughter cells for growth and repair. Meiosis creates four non-identical sex cells for reproduction. Mitosis ensures genetic stability, while meiosis introduces genetic diversity
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Know the relationship between molecular weight and rate of diffusion The rate of diffusion is inversely proportional to the molecular weight Small weight-fast diffusion; heavy weight-slow diffusion Identify RBC’s in various solution and determine tonicity Tonicity - the ability of an extracellular solution to make water move into or out of a cell by osmosis If a cell is placed in a hypertonic solution, there will be a net flow of water out of the cell, and the cell will lose volume (shrink). A solution will be hypertonic to a cell if its solute concentration is higher than that inside the cell, and the solutes cannot cross the membrane. If a cell is placed in a hypotonic solution, there will be a net flow of water into the cell, the cell will gain volume (bigger). If the solute concentration outside the cell is lower than inside the cell, then solutes cannot cross the membrane, then the solution is hypotonic to the cell. If a cell is placed in an isotonic solution, there will be no set flow of water into or out of the cell, and the cell’s volume will remain stable. If the solute concentration outside the cell is the same as inside the cell, and the solutes cannot cross the membrane, the solution is isotonic to the cell. Homeostatic feedback loop for respiratory rate, heart rate and temperature Respiratory Rate: Stimulus : The level of carbon dioxide (CO2) in the blood increases (often due to exercise or hypoventilation) . Receptors: Chemoreceptors in the medulla oblongata, carotid arteries, and aortic arch detect changes in blood pH and CO2 levels Control Center: The medulla oblongata processes this information Effectors: Respiratory muscles (diaphragm and intercostal) adjust breathing rate and depth Response: Increased respiratory rate removes CO2 and increases O2 intake, restoring normal pH and gas levels. Heart Rate: Stimulus : Changes in blood pressure, O2, CO2, or pH levels Receptors: Baroreceptors (detect blood pressure changes) in the carotid sinus and aortic arch; chemoreceptors monitor blood chemistry Control Center: The medulla oblongata (cardiac center) processes signals Effectors : The autonomic nervous system (ANS) adjusts heart rate through the sympathetic nervous system (increases heart rate) or parasympathetic nervous system (decreases heart rate) Response : Heart rate increases during low O2 or low blood pressure (to circulate oxygen) and decreases when homeostasis is restored. Temperature Regulation Stimulus: Changes in body temperature (hyperthermia or hypothermia) Receptors: Thermoreceptors in the skin and hypothalamus detect temperature fluctuations. Control Center: The hypothalamus processes this information and signals effectors Effectors and Responses: If too hot: Blood vessels dilate (vasodilation) to release heat, and sweat glands produce sweat for cooling If too cold: Blood vessels constrict (vasoconstriction) to retain heat, and shivering generates warmth. Steps of a generic homeostatic feedback loop Stimulus : A change in the internal or external environment that disrupts homeostasis (eg. temperature change, pH levels, blood sugar levels) Sensor (Receptor) : Specialized cells or receptors detect the change and send information to the control center. Control Center (Integrator): Often the brain or endocrine glands, this component processes the information from the sensors and determines the appropriate response to restore balance. Effector: This component carries out the response to the stimulus as dictated by the control center. Effectors can be muscles or glands that help to counteract the change. Response: The action taken by the effectors to restore homeostasis. This could involve increasing or decreasing a physiological process (e.g. sweating to cool down or shivering to warm up) Feedback: The results of the response are monitored. If homeostasis is restored, the system maintains its state; if not, the loop may repeat, continuing to adjust until balance is achieved. How to evaluate data to determine the set point, error, and disturbance Identify the set point The set point is the optimal level or range that the system aims to maintain. To determine the set point: Gather baseline data: Collect data over a period to understand the normal range for the variable in question (e.g. body temp., BP, blood glucose levels) Analyze Trends: Look for patterns in the data to identify the average or median value that represents the stable condition of the system. Consult Literature: Reference established physiological norms or previous studies to confirm the typical set point for the variable. Assess Disturbance A disturbance is any factor or event that causes a deviation from the set point. To evaluate disturbances: Identify External and Internal Factors: Analyze the data for any external influences (e.g. environmental changes, dietary habits) or internal changes (e.g. illness, stress) that might have impacted the variable. Quantity Disturbance: Measure the magnitude and duration of the disturbance. This can be done by comparing the data points during the disturbance against the established set point. Monitor Changes: Track how the system responds to disturbances over time to assess their impact on maintaining homeostasis. WBC types and normal distribution values/ abnormal values and what those values indicate (infections/diseases) (Never Let Monkeys Eat Bananas) Neutrophils (50-70%) - First responders to infections, especially bacterial. High levels indicate bacterial infections, inflammation, or stress. Low levels can indicate bone marrow disorders or severe infections. Lymphocytes (20-40%) - Include B cells and T cells, important for immunity. High levels can suggest viral infections or leukemia, while low levels might indicate immune deficiency. Monocytes (2-8%) - Help with cleaning up dead cells and fighting infections. High levels can be linked to chronic infections or autoimmune diseases. Eosinophils (1-4%) - Involved in allergic reactions and fighting parasites. Elevated levels may indicate allergies or parasitic infections. Basophils (0.5-1%) - Release histamine during allergic reactions. High levels might be see in allergic conditions or blood disorders. Normal WBC Count Total WBC Count: 4000-11000 cells per microliter of blood (varies slightly by lab) Leukocytosis (High WBC): Can indicate infection, inflammation, stress, or leukemia Leukopenia (Low WBC): Can result from bone marrow disorders, viral infections, or autoimmune diseases Neutrophils: Banded vs Segmented Neutrophils are the most abundant type of white blood cells and play a crucial role in fighting infections. They exist in different stages of maturation: Banded Neutrophils (“Bands”) - Immature Neutrophils Appearance: Have a curved, unsegmented nucleus (band-shaped) Normal Range: 0-6% of total WBC count (~0-700/uL) Clinical Significance: Increased Bands (Bandemia) -> Indicates an acute bacterial infection or severe stress (e.g. sepsis). The bone marrow releases immature neutrophils in response to infection. Low Bands -> Not clinically significant unless the total WBC count is low, which could suggest bone marrow suppression. Segmented Neutrophils (“Segs”) - Mature Neutrophils Appearance: Have a segmented nucleus with 2-5 lobes Normal Range: 50-70% of total WBC count (~2500-7000/uL) Clinical Significance: High Segs (Neutrophilia) -> Suggests bacterial infections, stress, chronic inflammation, or leukemia Low Segs (Neutropenia) ->Can be caused by viral infections, bone marrow disorders, chemotherapy, or autoimmune diseases. Discuss the stages of cell cycle/mitosis-which stages are longest/shortest The cell cycle is a series of events that cells go through to grow and divide. It consists of two main phases: Interphase (Longest Phase) – Preparation for division Mitosis (Shortest Phase) – Actual cell division Stages of the Cell Cycle Interphase (90% of the Cell Cycle – Longest Phase) Interphase is the period of cell growth and DNA replication. It has three subphases: G1 Phase (Gap 1) The cell grows, produces proteins, and prepares for DNA replication. Longest variable phase; some cells may stay here indefinitely (e.g., neurons in G0 phase). S Phase (Synthesis) DNA replication occurs, ensuring each daughter cell gets a complete genome. Takes about 6-8 hours in human cells. G2 Phase (Gap 2) The cell prepares for mitosis by producing proteins and organelles. Shorter than G1 but still significant in length. Mitosis: Prophase, Metaphase, Anaphase, Telophase Know proportional and inversely proportional relationships Direct (Proportional) Relationship When two quantities increase or decrease together at a constant rate, they are directly proportional. Inversely Proportional When one variable increases, the other decreases proportionally. Know relationship between molecular weight and rate of diffusion The rate of diffusion of a substance is inversely proportional to the square root of its molecular weight. Lighter molecules diffuse faster Heavier molecules diffuse slower due to greater mass. Know relationship between filtration rate and pressure of fluid or weight of fluid Filtration rate is directly proportional to the pressure or weight of the fluid driving the filtration process. Higher pressure → Higher filtration rate Lower pressure → Lower filtration rate Know why men and women blood values are different The differences in blood values between men and women are due to biological, hormonal, and physiological factors
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