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Viruses can:
infect everything, cannot multiple unless inside host
2 types of viruses:
Naked, and enveloped
enveloped viruses:
phospholipid bilayer, spike proteins, capsid,
Naked viruses:
capsid, genetic material
Capsid function
protects genetic material,
which influzena has a broad host range
influenza A
Broad specificity?
Can infect a different number of areas in the body
Binding:
virues attaches
penetration:
Gets inside via receptor mediated endocytosis
Uncoating:
Opening if the capsid (naked bring ezymes)
synthesis
copy genetic material of virus
Assmebly:
all viral parts get put together
DSDNA synthesis
uses host machinery to replicate and transcribe
-/+SSDNA (5to3and3to5)
DNA dependent polymerase to make compliment strand and transcribe. degrade other strand with enzyme
mRNA
uses RNA-dependent polymerase for replication. Can skip transcription and go right to translation
DS mRNA
Unwinds mRNA with helicase, uses RNA-dependent polymerase for replication. Ligate ligates it together with ligase. Degrades other strand for transcription.
cmRNA (capsid)
make double stranded with DNA dependent polymerase
Segmented RNA
Same as mRNA
retro viruses
mRNA to DNA through reverse trasncriptase. DNA into genome, Same as double stranded DNA
What can happen to cells infected with the virus?
synticia, where the cells fuse.
teratogenic effects?
substances that affect development
Prions are:
Beta pleated sheets
What is of viruses classification based on?
Nucelic acid type, single or double strand, + or -, enveloped vs naked
Double stranded virus
papovavirdae (HPV) He