Viruses.

Viruses can:

infect everything, cannot multiple unless inside host

2 types of viruses:

Naked, and enveloped

enveloped viruses:

phospholipid bilayer, spike proteins, capsid,

Naked viruses:

capsid, genetic material

Capsid function

protects genetic material,

which influzena has a broad host range

influenza A

Broad specificity?

Can infect a different number of areas in the body

Binding:

virues attaches

penetration:

Gets inside via receptor mediated endocytosis

Uncoating:

Opening if the capsid (naked bring ezymes)

synthesis

copy genetic material of virus

Assmebly:

all viral parts get put together

DSDNA synthesis

uses host machinery to replicate and transcribe

-/+SSDNA (5to3and3to5)

DNA dependent polymerase to make compliment strand and transcribe. degrade other strand with enzyme

mRNA

uses RNA-dependent polymerase for replication. Can skip transcription and go right to translation

DS mRNA

Unwinds mRNA with helicase, uses RNA-dependent polymerase for replication. Ligate ligates it together with ligase. Degrades other strand for transcription.

cmRNA (capsid)

make double stranded with DNA dependent polymerase

Segmented RNA

Same as mRNA

retro viruses

mRNA to DNA through reverse trasncriptase. DNA into genome, Same as double stranded DNA

What can happen to cells infected with the virus?

synticia, where the cells fuse.

teratogenic effects?

substances that affect development

Prions are:

Beta pleated sheets

What is of viruses classification based on?

Nucelic acid type, single or double strand, + or -, enveloped vs naked

Double stranded virus

papovavirdae (HPV) He