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what is the history of the opiod crisis
it is the current deadlist drug crisis in america
more american died of drug overdose in 2016 compared to Vietnam War
carfentanil
elephant tranquilizer
extremley potent and lethal
US zoos need only 18g/ year
hard to detect in toxicology
what are the stats with opoids missue?
21-29% will be prescribed for pain and will misuse them
8-12% develop an opiod use disorder
4-6% transition to heroin
drug dose by race 2021 and 2022
largest american
least asian non hispanic
opiod overdose death in the US
native american populations more likely to have state with overdose
highest rate West Virginia
This is because of the not healthy state of drugs and coal mining is popular, kids coal mine and they need pain meds
KY, NM, and CO too
what is it easier to do than get help
easier to avoid help , and also easier to find drugs
what did purdue pharma
makers of OxyContin knew that it was being abused (snorted) so they marketed as a non addictive drug
knew about the pills being crushed and snorted and continued to market OC
what is oxycontin
long acting drug to reduce pain , people wanted a severe long acting drug
not as addictive
drugs being abused, snorted or injected
what effect did the OC drug have on drugs
pressued by groups and the government to treat pain more seriously
amount of opiod prescribed per year were averaged out across 2-3 week supply this is because patients were seen quickly and efficiently
what country consumes the least amount of opiods
Greece
why do people even turn to opioids
24.3% of adults have chronic pain … 8.5% limited in life or work activities
safer non opioid pain treatment not available , insurance can be expensive
why do people take heroin and fent
treating chronic pain is hard , espeically when weighed against the risk of overdose and addiction
people who dont get opiods for the pain may not fully recover
need to control prescription opiod distribution while main thing access for patients
removing access to opiods who are dependent means that they will only get the very severe bad drugs (Fent and heroin)
what is the balloon efffect
when the drug is restricted users shift to alternatives
like pushing on balloon air moves but doesnt disappear
fentanyl
americans leading cause of overdose
suppose to relieve pain
2 mg enough to kill someone
some drugs can be laced with fentanyl
what age range uses heroin and fent the most
middle aged and older americans , much more likley to hit and 20-30 year olds
how can we treat and prevent
improving access to treatment and recovery
promoting use of overdose reversing drugs
need better pain treatment and understanding
fulll agonist drug
drug taking will bind to another drug
mimics natural neurotransmitters
most drugs of abuse are agonists
partial agonist drug
generates limit effect
partial effect not getting high but its blocking other opiods
antagonist
blocks the receptor of the drug
medication assisted treatment
use of meds with combo of therapies to provide a whole patient approach
what are some medicines to help people stop drugs?
methadone, burprenoprhine, and naltrexone
what is the negative of methadone, burp, and nalt
negative because giving drugs to people who want to take drugs
only taken orally
must be supervised — has to be prescribed
buprenorphine
can be provided at office based setting but DEA has to prescibe them
cap on # of the prescriptions that can be made
doesnt produce the sedation from heroin or fent
suboxone
another form of drug, trying to inject it will have a severe withdrawal symptoms
naltrexone
blocks opiods from binding to the receptors
not addictive, suppose to reduce ur craving
need to take orally
what is narcan
a way to reverse overdose , opioid antagonist binds to opoids receptors and can reverse and block the effects
very quickly restore normal respiration should still call emergency