Drug Suffixes + Some exam review

-olol

Beta Blockers end with—

-osin

Alpha 1 Blockers end with—

-opril

ACE Inhibitors end with—

-sartan

Angiotensin II Blockers end with—

-statin

HMG CoA reductase inhibitors lower LDL-C, are the first line of treatment, and end with—

-tide

Incretin mimetics (GLP-1 agonist) always end with—

That’s when the body produces cholesterol

Why are statins administered at night?

It has excellent bioavailability

Atorvastatin is the only statin that can be used in the day because—

Aliskiren

There is only one Renin Inhibitor, called—

Ranolazine

There is only one Sodium Channel Blocker, called—

-ipine

Calcium Channel Blockers end with—

Hypokalemia, hypercalcemia and hyperuricemia

What are the 3 adverse effects of nearly all diuretics?

One works mainly on the cardiac tissue, one works mainly on the vascular smooth muscle, and the last class works on both. (Diphennyalkylamines, benzothiazepines and dihydropyridines)

What differenitates the 3 calcium channel blocker classes?

Amlodipine; a dihydropyridine, for a long half life.

What calcium channel blocker should we remember?

Calcium channel blockers (amlodipine, diltiazem and verapamil)

What drugs are contraindicate in heart failure?

QT prolongation causes arrhythmias, and has numerous drug interactions.

Why is Ranolazine a last resort for anginal issues?

Metformin

The first line of treatment for type 2 diabetes is—