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Virus
A simple structure consisting essentially of a nucleic acid genome, protected by a shell of protein.
Virion
Infectious virus particle.
Capsid
Protein shell that surrounds and protects the viral genome.
Nucleocapsid
The combination of the viral genome and its capsid.
Envelope
Lipoprotein membrane surrounding some viruses, derived from the host cell's plasma membrane.
Glycoproteins
Proteins found in the envelope of the virion, usually glycosylated.
Helical morphology
A form of viral morphology seen in many filamentous viruses.
Icosahedral morphology
A symmetrical virus shape characterized by 20 triangular faces.
dsDNA
Double-stranded DNA viruses, such as Adenoviruses or Herpesviruses.
ssRNA
Single-stranded RNA viruses, including both positive and negative sense.
Viremic
The presence of virus in the blood.
Incubation period
The time from exposure to a virus to the onset of clinical symptoms.
Cell tropism
The specificity of a virus for a particular cell type, determined by receptor interaction.
Antibody response
The production of specific antibodies in response to a viral infection.
Pathogenesis
The process through which a viral infection leads to disease.
Immunocompromised
Individuals with weakened immune systems, making them more susceptible to infections.
Acyclovir
An antiviral medication used to treat infections caused by certain types of viruses, including herpes.
PCR (Polymerase Chain Reaction)
A laboratory technique used to amplify DNA sequences, often used for viral detection.
Vaccine
A biological preparation that provides active acquired immunity to a particular infectious disease.
Antisense molecules
Synthetic agents designed to bind to specific RNA molecules to inhibit virus replication.
Zoonosis
An infection that is typically transmitted from animals to humans.
Epidemiological pattern
The distribution and determinants of health-related states or events in specified populations.
Monospot test
A diagnostic test for infectious mononucleosis, typically detecting heterophile antibodies.
Hepatitis A Virus
A non-enveloped virus causing liver inflammation; transmitted via fecal-oral route.
Hepatitis B Virus
A virus that can cause chronic liver disease and is transmitted through blood and body fluids.
Human Immunodeficiency Virus (HIV)
A virus that attacks the immune system and can lead to acquired immunodeficiency syndrome (AIDS).
Retrovirus
A type of virus that inserts a copy of its RNA genome into the DNA of a host cell.
Viral attachment and entry inhibitors
Antiviral drugs that block the virus from attaching to or entering host cells.
Oncolytic viruses
Viruses that selectively infect and kill cancer cells.
Ribozymes
RNA molecules that can catalyze specific biochemical reactions.
Glycosylated
The process of adding carbohydrate groups to proteins, often important in viral structure.
T lymphocytes
A type of white blood cell that plays a central role in cell-mediated immunity.
Informal transmission
The spread of pathogens indirectly, through surfaces or other environmental means.
Antiviral agents
Substances that inhibit the replication of viruses.
Epidemiological study
Research designed to investigate the patterns, causes, and control of diseases in populations.
Neutralization
The process where antibodies bind to viruses and block their ability to infect host cells.
Core proteins
Proteins that are part of the inner structure of a virus, essential for its replication.
Humoral immune response
The aspect of immunity that is mediated by secreted antibodies produced by B cells.
Infectious mononucleosis
An illness caused by the Epstein-Barr virus, leading to symptoms like fever and sore throat.
Immunization
The process by which an individual's immune system becomes fortified against an infectious agent.
Filamentous viruses
Viruses that have a long, thin shape.
Poxviruses
A family of viruses that cause pox-like lesions in infected individuals.
Lipid solvents
Chemicals that can disrupt lipid membranes, often used to inactivate enveloped viruses.
Neuraminidase inhibitors
A class of antiviral drugs that prevent the release of viruses from infected cells.
Fomites
Inanimate objects or materials that can carry infection.
Chronic infection
An infection that persists over a long period, often without causing noticeable symptoms.
Resolution
The process of recovery from an infection.
Inoculation
Introducing a pathogen into the body for the purpose of establishing an infection or immunization.
Cytopathic effect
Visible effects of viral infection observed in a host cell.
Convalescence
The period of recovery after a disease.
Endemic
A disease or condition regularly found among particular people or in a certain area.
Epitope
The part of an antigen molecule to which an antibody attaches itself.
Natural selection
The process whereby organisms better adapted to their environment tend to survive and produce more offspring.