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ataxia
paresis
what are the 2 major gait abnormalities we see with neurological disease?
general proprioceptive
vestibular
cerebellar
what are the 3 major types of ataxia?
afferent neurons
ascending proprioceptive tracts (cord and brainstem, goes to forebrain as well for consciousness)
what do we need for normal proprioception?
cerebellum
brainstem
parietal lobe of the forebrain
where do the ascending proprioceptive tracts go to?
dorsolateral white matter of the spinal cord
where are the ascending tracts found?
PNS (out on the limb) or CNS (brainstem, cord)
where can lesions be for there to be proprioceptive deficits?
-look at cranial nerves
if normal, lesion is in c1-c5 cord
how do you know if the lesions is of the cord or the brainstem in an animal with proprioceptive deficits?
UMNs
LMNs
muscles
what is required for normal motor function?
the brain
where are UMN cell bodies located?
brainstem
where are the majority of the UMN centers located?
ventral and lateral parts of white matter
-deeper than ascending tracts
where are descending tracts located?
no
if they are its mild
if an animal has a forebrain lesion, will they be paretic?
profoundly
if an animal has brainstem lesion, will they be paretic?
brainstem
spinal cord
where can lesions be located that will have an effect on motor function?
-look at cranial nerves, mentation
if normal, lesion is in c1-c5 cord
how do you localize a lesion (brainstem or cord) that is resulting in UMN paresis?
flaccid paresis/paralysis
hyporeflexia to areflexia
hypotonia to atonia
neurogenic atrophy
list the lower motor neuron signs
spastic paresis/paralysis
normoreflexia to hyperreflexia
normotonia to hypertonia
dissuse atrophy
list the upper motor neuron signs
level of awareness, arousal, consciousness
what is mentation
lesions of brain/forebrain
what leads to changes in mentation
alert and responsive (normal)
obtunded (depressed)
stuporous (semi-comatose)
comatose
what are some descriptors that clinicians use to describe mentation?
ARAS (in the brainstem)
where is the starting point for normal mentation?
cortical neurons found in the cerebral cortex of the forebrain
what are the target neurons for the ARAS?
reticular formation
where do all sensory systems "feed into"?
-relay into all cerebral cortex areas
and keeps the cortex "awake"
once the reticular formation neurons are activated, what do they do?
the lesion would reduce the amount of info that the cortical neurons are getting, so there would be a drop in mentation
How would a lesion in the brainstem affect the cortical neurons?
might not see any change in mentation
How would a lesion in the cerebral cortex affect mentation?
if its really big or diffuse (encephalitis)
when would a lesion in the cerebral cortex affect mentation
PLR and oculocephalic
which cranial nerve reflexes are the last to go when there is a lesion?
-tap skin in c1-c3 vertebral area
-should see ears flick forward
- efferent is facial nerve (CN VII)
Upper cervical reflex
-what do you do
-what should be the response
-what is the efferent nerve
- tap skin cranial to the shoulder
- contraction of brachiocephalicus m.
- afferent/efferent c3-c6 spinal nerves
Lower cervical reflex
-what do you do
- what should be the response
- what is the afferent/ efferent nerves
c1-c5 cord
what is the thoracolaryngeal reflex useful in evaluating?
slap test
another name for thoracolaryngeal reflex
-gently slap just caudal to the wither during expiration
- brief adduction of contralateral arytenoid cartilage
-afferent: dorsal branch of thoracic spinal nerve
-efferent: CN X
-How do you preform the thoracolaryngeal reflex
-what should be the response
-afferent
-efferent
-shine really bright light into eye
- animal should pull head and neck away and blink
-afferent: CN II
-efferent: cervical cord LMNs and CN VII (medulla)
Dazzle reflex
-how to preform
-what should be the response
- afferent nerve
-efferent