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toxicity
a measure of how toxic something is to living organisms
dose
the total amount of chemical to which an organism is exposed
dose/response assays
experiments in which test organisms are exposed to various amounts of the chemical and biological changes caused by that exposure are measured
acute effects
caused by exposure to a single dose
chronic effects
develops slowly due to long term exposure
major routes of exposure
oral, dermal, inhalation, injection
therapeutic index
TD50/ED50
TC50
toxic concentration
ED50
effective dose where 50% of the population experiences a specific effect