Lecture 15: Variations in Mendelian inheritance of dominant alleles

What are the 5 different Patterns of Mendelian inheritance?

1. Autosomal dominant

2. Autosomal recessive

3. X- linked dominant

4. X-linked recessive

5. Y-Linked

What are 4 Dominant inheritance concepts?

1. Complete dominance

2. Incomplete dominance

3. Incomplete/Partial dominance

4. Co-dominance

What is Complete dominance?

Dominant allele had the same phenotypic effect whether it was present in 1 or 2 copies

Explain Incomplete dominance

Phenotype is a mix between phenotypes of both parents ( none is more dominant than the other)

eg Red and white flowers are crossed, the F1 generation produce pink offspring

Give an example of Incomplete dominance

Hypercholesterolemia

What is Hypercholesterolemia?

Dangerously high levels of cholesterol in the blood

LDL meaning

low density lipoproteins, cholesterol containing particles in the blood

What is Incomplete/Partial dominance?

Neither trait is truly dominant over the other

Explain Co-dominance

• Both alleles are expressed

• Neither allele is dominant over the other

What gene is responsible for making your blood group?

ABO blood grouping