epidemiology
the study of the distribution and determinants of disease. This is critically important in population health science
biostatistics
a related science focused on understanding variability in potential causes and outcomes in order to infer associations and relationships among them
Step 1 of the 5 step approach
Define the population
Step 2 of the 5 step approach
Define and measure the health outcome and potential causes of health
Step 3 of the 5 step approach
Take a sample from the population for analysis
Step 4 of the 5 step approach
Evaluate potential causes of population health
Step 5 of the 5 step approach
Identify targets for public health action
Defining the population
target group: age, gender, location, presence of condition, etc.
Define and measure the health outcome and potential causes of health
Looks at what is being measured, how evidence/frameworks explain potential causes of health, uses indicators and statistics
Take a sample from the population
Use a small section of the population to calculate prevalence
Evaluate potential causes for health
use data to evaluate how diverse factors cause a particular health outcome
Identify targets for public health action
Look at modifiable factors and what can be done
incidence
new cases
recovery
when people no longer have the disease
prevalence
the number of cases
mortality
death
cross-sectional study
participants are representative of the population defined by
person, place, and time looks at prevalence
cohort study
participants are free of the outcome of interest and followed over time for the development of that outcome, looks at prevalence of causes and incidence of health outcome
case-control study
cases are participants with the health outcome of interest and controls are a random sample of participants from the same population that produced the cases but are free of the outcome, looks at association between cause prevalence and outcome
confounding factors
variables that may compete with the exposure of interest (eg, treatment) in explaining the outcome of a study
randomised trials
participants are randomized to receive the intervention or not and followed for incidence of the health outcome or disease progression, looks at effect of intervention