Types of Introns and Splicing Mechanisms

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4 Terms

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What are group I introns?

are self-splicing introns that use a free guanosine as a cofactor to initiate cleavage and ligation without a spliceosome.

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What are group II introns?

are self-splicing ribozymes that form a lariat intermediate similar to spliceosomal splicing, but they do not require proteins.

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How does snRNA-mediated splicing differ from group I and II introns?

snRNA-mediated splicing occurs in spliceosomes that use snRNAs as catalysts, while group I and II introns self-splice without protein complexes.

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