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cell cycle
a regular pattern of growth, DNA replication, and cell division
How many main stages does the cell cycle have
four
What are the four main stages of the cell cycle
Gap 1, Synthesis, Gap 2, Mitosis
What stages make up interphase
Gap 1, Synthesis, Gap 2
Gap 1
Cell growth, organelle replication, and normal functions
synthesis
DNA replication
Gap 2
additional growth and normal functions
mitosis
cell division
mitosis the process
division of the cell's nucelus
cytokinesis
division of the cells cytoplasm
what do mitosis and cytokinesis produce
2 genetically identical daughter cells
Gap 0
normal functions, no preparation for division
chromosome
one long, continuous thread of DNA
How many chromosomes do humans have per body cell
46
chromatin
DNA plus proteins
what does chromatin do
helps organize and condense DNA
chromatid
one leaf of a duplicated chromosome
sister chromatids
two identical chromatids of the duplicated chromosomes
centromere
region of the chromosomes that holds the two sister chromatids together
telomeres
ends of the chromosomes that do not include genes and act to protect DNA
interphase
preparation for cell division
spindle fibers
consist of microtubules and proteins; make up the mitotic spindle
centrosomes
organizing center for the microtubules that make up the mitotic spindle
centrioles
made up of microtubules, appear to play a role in the duplication of centrosomes in animal cells
prophase
chromosomes condense, nuclear membrane breaks down, spindle fivers form
metaphase
chromosomes line up in the middle of the cell
anaphase
sister chromatids separate to opposite sides of a cell
telophase
new nuclear membranes form and chromosomes begin to uncoil; cytokinesis is also occurring
____ factors trigger ____ factors
external factors trigger internal factors
physical examples of external factors
cell-to-cell contact
chemical example of external factors
growth factors and hormones
internal factors
include several types of molecules in the cytoplasm
kinases and cyclins
most important molecules in internal factors
Apotosis
programmed cell death
what is apoptosis caused by
cell's production of self-destructive enzymes
who does apoptosis occur in
adults and the development of embryos
cancer
class of diseases characterized by uncontrolled cell division
what happens to a single normal cell when damage occurs to genes involved in cell-cycle regulation
it is transformed into a cancer cell
how does radiation work
damages cell's DNA so the cell cant divide
what makes chemotherapy "systemic"
drug travels throughout the body