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Year 1 - Normal Animal
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fresh weight
weight of food as it is prepared i.e. when fed to an animal
dry matter
weight of food without any water present
energy balance
when total energy provision of an animal is equal to the total energy it needs, if provision is greater than needs there is a positive energy balance (PEB) and if lower than needs then tehre is a negative energy balance (NEB)
gross energy
amount of energy present in food before consumption, measured using bomb calorimetry to calculate energy released by oxidation of covalent bonds
digestible energy
amount of energy present after consumption due to faecal energy loss
metabolisable energy
the energy assimilated by the animal and which is available to fuel metabolism after energy loss through urine and belching/flatulence
factors affecting metabolisable energy
digestibility (species, fibre content, plane of nutrition, feed preparation), diet quality, species (i.e. monogastric/ ruminant), nitrogen balance, food preparation, feeding levels
heat increment of feeding
heat produced by the digestion of food, as energy must be used
net energy
all of the dietary energy available to the animal when the costs of digestion, metabolism and wastage have been accounted for
practical ways to measure net energy
net energy is hard to measure so metabolisable energy is measured in ruminants, poultry, dogs and cats and digestible energy is measured in horses and pigs
formula to calculate dry matter weight
fresh weight x dry matter proportion
formula to calculate fresh weight
dry matter weight/ dry matter proportion
metabolic rate
the total conversion of energy in the body per unit time
basal metabolic rate
amount of energy expended to keep an animal alive, measured when animal is not moving, not stressed, within thermoneutral zone and post absorptive state
fasting metabolic rate
amount of energy expended when an animal has a low level of activity
maintenance metabolic rate
energy expended when an animal is eating exactly the amount of food needed to maintain a constant body mass
ways to measure metabolic rate
direct calorimetry; measure of heat production by animal in a calorimeter, indirect calorimetry; estimating the heat produced from respiratory exchanges in a calorimeter
factors affecting metabolic rate
size (smaller increases rate), age, activity
energy costs in addition to maintenance in livestock animals
growth and fattening, lactation, gestation, wool growth, egg production, thermal stress
vitamins
organic compounds required in very small quantities for normal body function, will be fat or water soluble
which vitamins are water soluble?
B and C
which vitamins are fat soluble?
A, D, E and K
vitamin C chemical name
ascorbic acid
vitamin B1 chemical name
thiamine
vitamin B2 chemical name
riboflavin
vitamin B3 chemical name
nicotinic acid/ niacin
vitamin B5 chemical name
pantothenic acid
vitamin B6 chemical name
pyridoxine
vitamin B7 chemical name
biotin
vitamin B9 chemical name
folic acid
vitamin B12 chemical name
cyanocobalamin
provitamins
compounds that act as vitamins only after undergoing chemical change to active forms in the body
avitaminosis
total absence of a vitamin
hypovitaminosis
partial lack of a vitamin, often shown by non-specific signs of ill health which don’t always relate directly to the vitamin’s metabolic function
hypervitaminosis
excessive provision of a vitamin
metabolic functions of retinol
formation and integrity of epithelia and mucous membranes, retinal function (combines with opsin to form rhodopsin), bone growth, immune function
factors affecting vitamin requirements of an animal
health, age, production, rate of growth, speed of food passage through gut
beta carotene
pro-vitamin A which is converted to retinol during absorption through the gut wall, however the ability to do this varies with age, species, breed and health
where is retinol stored?
in the liver
sources of retinol
liver, egg yolk, milk fat, beta carotene in plants
retinol deficiency in cattle
symptoms: rough scaly skin, night blindness, lachrymation, corneal opacity, infertility, abortion, retained placenta, still-birth
rare in adults as they acquire carotenoids at pasture so can provide adequate retinol over winter periods but intensively reared indoor beef cattle on cereal diets are more prone
symptoms of retinol deficiency in dogs
dry, scaly skin, night blindness, abnormal skeletal growth
symptoms of retinol deficiency in cats
foetal defects or complete infertility
retinol deficiency in poultry
symptoms: pale comb and wattles, loss of condition, slowed growth, ruffled plumage, susceptible to infectious diseases
high mortality rate
symptoms appear after 2-3 weeks
effects of hypervitaminosis A in dogs and cats
abnormal bone deposition, lameness, vertebral spondylosis, gingivitis, weight loss, poor coat
effect of hypervitaminosis A in pregnant sows
cardiac abnormalities in piglets
biological molecules classed as vitamin D
calciferols
sources of vitamin D
sunlight, oily fish, egg yolk, hay, colostrum
metabolic functions of vitamin D
promotes calcium ion absorption from digesta in the gut lumen, enhances intestinal absorption of calcium when blood calcium concentration decreases, stimulates phosphorous uptake from gut and reabsorption of calcium and phosphorus from bones and kidneys
problems caused by vitamin D deficiency
rickets (soft weak deformed bones in young growing animals), osteomalacia in adults (weak bones), poor egg shell quality and weak bones in poultry
vitamin E chemical name
tocopherol
metabolic functions of vitamin E
biological antioxidant, acts in combination with glutathione peroxidase to protect cells from oxidative damage caused by free radicals, important for reproductive and muscular function and capillary integrity
problems caused by vitamin E deficiency
white muscle disease and mulberry heart disease in calves, stiff lamb disease in lambs, mulberry heart disease in pigs, crazy chick disease in poultry, tying-up in horses
group of molecules that are vitamin K
quinones
sources of vitamin K
green, leafy materials, egg yolk, liver, fish
metabolic functions of vitamin K
essential for normal clotting of blood, bone and kidney function
signs of vitamin K deficiency in chicks
anaemia and delayed clotting of blood
sources of vitamin E
green doffer, cereals
why are B vitamin deficiencies only seen in pre-ruminant young and sick ruminants?
rumen bacteria can synthesise B vitamins in sufficient quantities
metabolic function of vitamin B1/thiamine
initiation and propagation of nerve impulses
signs of vitamin B1/thiamine deficiency
progressive dysfunction of nervous system, paralysis, blindness, muscular dysfunction, loss of appetite, emaciation
how can adult ruminants develop vitamin B1 deficiency?
bacterial thiaminases produced in disturbed rumen microflora destory ingested and bacterial thiamine
metabolic function of vitamin B2/riboflavin
vital for oxidative phosphorylation and proton transport
signs of vitamin B2 deficiency in pigs
poor apetite and growth, skin eruptions, vomiting, eye abnormalities, infertility and abortion
metabolic function of cyanocobalamin
important coenzyme in cellular respiratory pathways
signs of vitamin B12 deficiency
poor growth in young animals mostly
sources of vitamin B12
food of animal origin, microbial as long as cobalt is present in diet
sources of vitamin C
citrus fruits, green leafy vegetables
metabolic functions of vitamin C
normal collagen formation, metabolic oxidation and reduction pathways, iron transport, antioxidant
which animals need vitamin C in their diet?
primates, guinea pigs and fruit bats (other species synthesise it from glucose)
signs of vitamin C deficiency
scurvy, lethargy, muscle and joint pain, red dots on skin, bleeding and swelling of gums, diarrhoea, weight loss, rough hair coat, reduced immune function
signs of vitamin B2 deficiency in chicks
curled toe paralysis
signs of vitamin B2 deficiency in ruminants
inappetence, diarrhoea, mouth lesions
signs of vitamin B6 deficiency
neural degeneration and jerky gait in chicks, rare due to wide distribution and gut microbial synthesis
2 types of essential minerals
macro and micro
functions of calcium
structural component of skeleton, controls cell excitability, regulates muscle contraction, regulates blood coagulation, many enzyme actions
sources of calcium and phosphorus in an ideal ratio
leafy greens, hay, animal products
corrective sources of calcium
limestone flour, soluble grit for poultry
factors affecting absorption of calcium
plant calcium can be bound as phytates which prevents absorption in monogastrics, oxalates bind to calcium to form insoluble salts, total absorption of calcium and phosphorus decreases as dietary concentration becomes excessive, high fat diets as fatty acids bind to calcium, enteritis - inflamed mucosa can’t absorb calcium
causes of hypocalcaemia
female mammals at onset or peak of lactation, laying hens due to eggshell production
milk fever
sudden hypocalcaemia in dairy cows before/shortly after calving caused by high demand for calcium due to lactation, causes flaccid paralysis, recumbency, rumen stasis, pupil dilation
chronic hypocalcaemia
occurs in growing animals due to high rate of skeletal growth which causues osteodystrophy (abnormal bone growth) and rickets (failure of bone to ossify)
causes of osteodrystrophies in puppies/kittens
excessive phosphorus causes a secondary calcium deficiency
factors affecting absorption of phosphorous
oxalates and phytates cause lots of plant phosphorus to be organically bound as salts of phytic acid, excess dietary calcium inhibits absorption of phosphorus
signs of phosphorus deficiency
abnormal bone growth, osteomalacia, reduced growth rates, abnormal appetites, infertility
functions of magnesium
most common enzyme activator, allows muscle contraction, propagation of nerve impulses
sources of magnesium
green plants, meat and bone, colostrum, magnesite, no body reserves
major presentations of hypomagnesaemia
calves fed all-milk diets (poor source of magnesium)
beef cattle and sheep fed on low quality roughage/fodder crops, causes dullness, hyperaesthesia, convulsions, death
lactating cattle and sheep, hyperaesthesia, incoordination, muscle tremor, recumbency, convulsions, sudden death, ‘grass staggers’
causes of grass staggers
rapid grass growth, grass diarrhoea, bad weather, fertilisers (nitrogen increases rumen NH3 which decreases Mg uptake, potassium increases Mg excretion, liming decreases grass Mg concentration), gradual decrease in grass magnesium in autumn, stresses which decrease food intake
ways to reduce hypomagnesaemia
provide shelter, introduce to spring grass slowly, use fertilisers with care, porvide mineral licks, top dress pastures, increase clover in swards, supplement diet or water with mg, Mg rumen boluses, avoid stress
functions of copper
important for formation of plasma proteins, component of other blood proteins, plays a role in oxygen metabolism, role in many enzyme systems, essential for normal hair, wool and feather pigmentation, essential for immune function
most readily absorbed form of copper
copper sulphate
transport of copper in the body
loosely bound to albumen in plasma and stored and released from liver to meet body requirements
signs of copper deficiency
anaemia, abnormal bone growth, abnormal hair, feather and wool growth, loss of hair pigmentation, cardiovascular disease
swayback
disease affecting lambs born to copper deficient ewes which causes failure or degeneration of normal neural development in lamb or stillborn, depressed growth rate, rapid onset hind limb weakness, ataxia then paresis and death
signs of copper deficiency in calves
failure to thrive, poor growth, stiff gait/lameness, loss of hair pigment (causes a speckled appearance)
effect of molybdenum on copper absorption
rumen microbes form sulphides which combine with molybdenum to form thiomolybdate which binds copper to form copper thiomolybdate which decreases copper absorption and causes signs of copper deficiency despite adequate dietary copper provision
animals with the worst copper toxicity tolerance
sheep (then cattle, horses then pigs)
signs of copper toxicity
jaundice, appetite loss, hepatic coma and death
nutrient
any chemical element or compound in the diet that supports normal reproduction, growth, lactation or the maintenance of life processes