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Skeletal Cartilage
Exhibits chondrocytes housed in lacunae (cavities) within extracellular matrix (ground substance and fibers). It contains large amounts of water (which accounts for resilience), lacks nerve fibers, is avascular, and is surrounded by a fibrous perichondrium that resists expansion
Hyaline cartilage
Appear glassy; the fibers are collagen. They provide support with flexibility and resilience and are the most abundant skeletal cartilage, accounting for the articular, costal, respiratory, and nasal cartilages
Elastic Cartilage
Abundant elastic fibers, in addition to collagen fibers, more flexible than hyaline cartilages. Support outer ear and epiglottis
Fibrocartilages
Contain thick collagen fibers, are the most compressible cartilages and are resistant to stretch. They form vertebral discs and knee joint cartilages.
Appositional growth
Surrounding cells in perichondrium secrete new matrix on outside
Interstitial Growth
The lacunae-bound chondrocytes divide and secrete new matrix, expanding the cartilage within. Ends during adolescence.
Long Bones
Limbs, longer than they are wide
Short Bones
roughly cube shaped; Wrist and ankle bones
Sesamoid bones
Special short bone that form in a tendon. Patella
flat bone
Thin flattened, and usually a bit curved. Sternum, scapular, ribs, and skull bones
Irregular bones
Complicated shapes.Vertebrae and hip bones
Functions of Bones
Bones give the body shape, protect and support body organs, provide levers for muscles to pull on, store calcium and other minerals, and are the site of blood cell production
Diaphysis
shaft forms along axis of bone. Contains thick collar of compact bone that surrounds medullary cavity.
Medullary Cavity
Marrow cavity. Contains yellow bone marrow.
Epiphyses
Bones ends. Contains spongy bone
Epiphyseal line
Remnant of Epiphyseal plate.
Epiphyseal plate
Disc of hyaline cartilage that grows during childhood to lengthen bone.
Periosteum
white, double layered membrane covering bone. Outer fibrous layer is dense irregular connective tissue. Inner osteogenic layer, consists of osteoblasts and osteoclasts.
Nutrient Foramen
Nerve fibers, lymphatic vessels, and blood vessels enter vie foramen
Endosteum
Covers trabecuale of spongy bone and lines canal cavities has both osteoblasts and osteoclasts.
Red marrow
Hematopeitic tissue is found within the diploe of flat bones and occasionally within the epiphyses of long bones. In infants red marrow is in medullary cavity.
Osteon or Haversian System
Cylinder, weight bearing pillars. Group of hollow tubed of bone matrix
Lamella
Each tube in bone matrix of osteon
Lammalar bone
compact bone
Central Haversian canal
Runs through core of Osteon has small blood vessels and nerve fibers for cells.
Perforating or Volkmann's canals
Connect blood and nerve supply of the periosteum to the central canals
Lacunae
Junctions of lamellae, contain osteoctyes
Canaliculi
Hairlike canals connect lacunae together
Bone matrix
osteoid, organic substances produced by osteoblasts and give the bone tensile strength and give the bone tensile strength. Inorganic hydroxyapatites (Ca salts) make the bone hard
Intramembranous ossification
Forms cranial bones and clavicles.
1. An ossification center appears in the fibrous connective tissue membrane
2. Bone matrix is created within fibrous membrane
3. Woven bone and Periosteum form
4. Bone collar of compact bone forms and red marrow appears
Endochondral ossification
Uses hyaline cartilage bones as models.
1. Formation of bone collar around hyaline cartilage model
2. Cavitation of the hyaline cartilage within the model
3. Invasion of internal cavities by the periosteal bud and spongy bone formation
4. formation of the medullary cavity as ossification continues; appearance of secondary ossification in the epiphyses
5. ossification of the epiphyses when completed, hyaline cartilage remains only in the epiphyseal plates and articular cartilage.
Bone remoldeling
New bone continually being deposited and reabsorbed in response to hormonal and mechanical stimuli.
Bone deposit
Osteoid seam appears then Ca salts are deposited a few days later
Osteoclasts
Release lysosomal enzymes and acids on bone surface. The dissolved products are released to extra cellular matrix
Hormonal control of Ca levels
Blood Ca declines, PTH is released and stimulates osteoclasts to digest bone matrix. Blood Ca levels rise, calcitonin releases, stimulated removal of Ca from blood.
Stages of Healing a Bone Fracture
1. Hematoma formation
2. Fibrocartilage callus formation
3. Bony Callus formation
4. Bone remodeling
Osteomalacia / Rickets
Caused by inadequate minerals. The bones become soft and deformed. Often inadequate Vitamin D.
Osteoporosis
Any condition in which the bones breakdown outpaces bone formation, causing bones to become weak and porus.
Pagets Disease
Excessive and abnormal bone remodeling