Donor Selection and Testing

Collections and processing are governed by

Collections and processing are governed by

FDA, AABB, CAP

Retention times

5 years for approval for donation interval

HIV and Travel from another country forever

10 years for everything else

Donor screening

Mini physical, serologic blood testing , registration, med history

Registration

Full ID, confirm ID, DOB (16-17), consent, record differal reasons, other (directed donor, race, CMV status)

Informed consent

Risk, questions, comprehension, signs and symptoms of infection, tests that will be done/ agencies notified of +

Weight req

110 lbs (max 10.5mL)

Temp req.

37.5> / 99.5

Pulse range

500-100 bpm

Blood pressure

<180/100 mm Hg

H/H females

>12.5 g/dL and 38%

H/H males

>13.0 g/dL and 39%

H/H auto donation

11 g/dL and 33%

Donation interval for whole blood

8 weeks

Donation interval for 2 unit apheresis

16 weeks

Travel risks

Malaria, HIV, vCJD, and Leishmania

Medication that risks the donor

Blood thinners and replacements

Conditions

Cardio, cancer, preg, infectious diseases

Temporary deferral

Donor unable to donate for a limited time

Indefinite deferral

Unable to donate for an unspecified amount of time due to current regulatory req

Permanent deferral

Never able to donate for someone else

Deferral for NSAIDs and aspirin

3 days

Deferral for live vaccination Measles, mumps, polio, or yellow fever

2 weeks

Deferral for rubella (German measles)

4 weeks

Deferral after pregnancy

6 weeks

Deferral for 1 unit whole blood

8 weeks (56 days)

Deferral after double RBC apheresis

16 weeks

12 month deferrals

Dirty tattoos or piercings and jail

Permanent deferrals

Growth hormone, HBsAg, HepC, xenotransplantation

Informed consent FDA req

Signed consent form, procedure explained and understood, accurate and truthful answers

Directed donations if related

Irradiated

Donor follow-up

Post donation instructions and donor reactions

Whole blood collections

Packed RBCs, plasma, platelets, cryoprecipitate

Apheresis collection

RBCs, stem cells, platelets, plasma, granulocytes

Interval between platelet, plasma, or leukocyte donations

2 days but not exceeding 2x a week or 24x a year

Whole blood, thawed plasma, and RBC storage temps

1-6°C

Frozen red cell storage temps

-65 or -120° depending on glycerol

Platelet storage

Agitated at room temp

Granulocyte storage

Room temp

When are component labels put on

At donor center

AS1 AS3 and AS5 expiration

42 days

ACD CPD and CP2D expiration

21 days

CPDA1 expiration

35 days

Donor testing

ABO/Rh antibody screen and viral markers

Auto units taken before surgery occurs

5-6 weeks before and no later than 3 days before