morimori
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59 Terms
1
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the generation of ( ), ( ), and ( ), occurs in the 3rd week after fertilization
trilaminar disk, notochord, neural plate
2
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at around 18 days, the ( ) is stuffed with cells to form a mature notochord.
notochordial process
3
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what are the 3 roles of the notochord?
determine the central axis
induce neurogenesis
induce floor plate
induce neurogenesis
induce floor plate
4
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when is the neural crest formed?
end of the 3rd week.
5
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how is the neural crest formed?
the rostal and caudal neuropores close
6
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notochord differentiates the ectoderm into...
neural tube
7
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the notochord differentiates the somite into...
skeletal muscles and bones
8
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the somite is filled with...
paraxial mesoderm
9
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in the neural tube, neural cells on the ( ) side divide.
luminal
10
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nervous cells outside the neural tube are derived from the...
neural crest
11
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nervous cells in the neural tube develop into...
CNS
12
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neural crest develops into...
schwann cells
melanocytes
adrenal medulla
melanocytes
adrenal medulla
13
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the dorsal part of the neural tube is called the ( ) plate.
roof
14
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the ventral part of the neural tube is called the ( ) plate
floor
15
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the central canal is covered with....
ependymal monolayer cells
16
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the 3 layers of the neural tube from inner to outer:
ventricular, intermediate, marginal
17
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the 4 plates of the neural tube, from dorsal to ventral
roof, alar, basal, floor
18
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the basal plate matures into the ( ) horn. the floor plate matures into the ( ) horn.
ventral, dorsal
19
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an ectopic Shh expression leads to the expression of
an extra floor plate
20
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BMPs are secreted from ( ) side of neural tube
dorsal
21
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Shh are secreted from ( ) side of neural tube
ventral
22
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the roof plate secretes...
BMP and Wnt
23
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( ) is the ansence of brain due to the incomplete closure of ( ) neuropore
meroencephaly, rostal
24
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meningomyelocele is due to the incomplete closure of ( ) neuropore
caudal
25
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the proencephalon first differentiates into...
telencephalon and diencephalon
26
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the mesencephalon becomes ...
midbrain
27
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the rhombencephalon differentiates into...
metencephalon and myelenephalon
28
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the telencephalon becomes...
cerebrum
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the diencephalon becomes...
thalamus, hypothalamus, (epithalamus)
30
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the metencephalon becomes..
pons and cerebellum
31
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the myelencephalon becomes...
the medulla oblongata
32
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what are the 3 flexures formed in the neural tube?
cephalic, cervical, pontine
33
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at 6-8 weeks, the ( ) is formed int eh metencephalon, which later becomes the cerebellum
rhombic lip
34
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during neuronal migration, the inside is ( ) and outside is ( )
early, late
35
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the neurons divide in the ( ) layer of the neural tube, then migrate to the ( ) layer
ventricular, plial
36
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the 3 steps of propagation of neurons
extension of leading
movement of nucleus
retraction of rear process
movement of nucleus
retraction of rear process
37
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what is reelin?
glycoprotein secreted from the extrecellular matrix that regulates neuronal migration
38
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what is the cause of lissencephaly?
due to a defect in cell migration, which leads to inverted layer formation
39
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up the the 3rd week, rathke's pouch grows dorsally to the ( )
infundibulum
40
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what happens to rathke's pouch after 2 months?
it loses connection with the oral cavity but stays close with the infundum
41
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the optic vesicles and optic cup induces ( ) from the surface ectoderm
lens placode
42
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at 3 weeks the optic ( ) has formed
groove
43
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the optic groove comes in contact with the ( ) to induce differentiation
surface ectoderm
44
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the optic cup is formed when the ( ) invaginates
optic vesicle
45
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the inner layer of the optic cup forms the ( )
retina
46
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the outer layer of the optic cup forms...
choroid and retinal pigment epithelium
47
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function of PAX-6
regulation of eye development
48
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the optic placode comes from the surface ectoderm of the ( )
hindbrain
49
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the optic placode invaginates to form...
optic pit, optic vesicle
50
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the inner ear is derived from
optic pit and optic vesicle
51
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the middle ear is derived from...
endodermal 1st pharyngeal pouch
52
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the mallues and incus derives from the ( ), but the stapes derives from ( ).
1st pharyngeal arch, 2nd pharyngeal arch
53
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the 1st pharyngeal pouch develops into the auditory tube, then it becomes...
tympanic cavity
54
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the 1st pharyngeal groove develops into the external ( ), when them becomes the external ear
acoustic meatus
55
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the auricle (visible part of ear) is derived from...
auricular hillock
56
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2 origins of the skull?
mesoderm
neural crest (ectoderm)
neural crest (ectoderm)
57
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head regions rostal to the rathke's pouch has no components derived from ( ).
mesoderm
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head regions anterior to the pituitary gland are derived form ( )
neural crest
59
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head regions posterior to the pituitary gland are derived from ( )
paraxial mesoderm
Note 
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