Histology

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78 Terms

1
How many cells have a nucleus?
less than 75%
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2
Cells that connect body parts or cover/line organs
  • erythrocytes

  • fibroblasts

  • epithelial cells

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3
Cells that move organs and body parts
  • skeletal muscle cell

  • smooth muscle cell

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4
Cell that stores nutrients
fat cell
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Cells that fight disease
Monocytes
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Cell that gathers information and controls body functions
Nerve cell
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Cells of reproduction
  • sperm

  • ovary

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8
Tissue
- group of cells that work together to perform a specific function
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Histology
- study of tissues
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10
Epithelial Tissue
  • lines walls of open tubes, body surfaces and all body cavities

  • lines the vessels of the secretory system and digestive system

  • provides secretory and absorptive surfaces

  • possess little to no extracellular matrix

  • avascula

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Functions of Epithelial Tissue
  • physical protection as a barrier

  • reduces dehydration and abrasion

  • protects from physical, chemical and biological agents

  • absorption, regulating the passage of certain molecules in out of the body

  • secretion of sweat or oil or digestive enzymes

  • have nerve endings that can detect various sensations

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Main Characteristics of Epithelial Cells
  • tightly packed to ensure a barrier and absorptive/secretive functions

  • organized assembly of apical, basal and lateral surfaces

  • exhibits polarity which is necessary for selective movement of molecules

  • highly regenerative to repair damage at a rapid rate

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Apical Surface
- top of epithelial cells that faces the body surface, body cavity, lumen of the internal organ or duct
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Lateral Surface
- part of epithelial cells that contains junctions to communicate with other cells
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Basal Surface
- apart of the epithelial cells that adheres to the basement membrane
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Basement Membrane
  • made of 2 different layers from different cells the basal lamina and reticular lamina

  • supports epithelial cells

  • provides surface for cell movement

  • restricts the passage of substances between epithelial and connective tissue

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Reticular Lamina
  • bottom layer of the basement membrane

  • formed by cells in connective tissue

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Basal Lamina
  • upper layer of the basement membrane

  • formed by epithelial cells

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Covering Epithelia
  • cells arranged in layers that cover external surfaces or line the cavities of the body

  • characterized by the number of cells layers that make up the tissue and the cell shape

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Single Epithelium
- single layer of cells with all cells attached to the basement membrane
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Stratified Epithelium
  • two or more layers of cells

  • only the bottom layer is attached to the basement membrane

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Pseudostratified Epithelium
  • single layer but not all cells reach the apical surface

  • nuclei looks like multiple layers but there is only one

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Squamous Epithelium
  • flattened egg shape

  • flat nuclei

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Cuboidal Epithelium

-about the same size on all sides

  • nucleus is centrally located

  • round nuclei

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Columnar Epithelium
  • cells are taller than they are wide

  • nucleus is oval and located in the basal region

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Simple Squamous Epithelium
  • single layer of flat disc-like cells with a flattened nuclei

  • surface for filtration and diffusion

  • found in alveoli, glomeruli nephrons, blood vessel and capillary lumens, body cavity linings

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Simple Cuboidal Epithelium
  • single layer of cube-like cells with large, round nuclei

  • responsible for secretion and absorption

  • found in ducts and glands, kidney tubules, ovary and thyroid

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Simple Columnar Epithelium
  • single layer of tall rectangular cells with an elongated nuclei

  • microvilli and cilia common on apical surface

  • for absorption and secretion

  • mainly in the lining of the digestive and respiratory tract

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Pseudostratified Columnar Epithelium
  • single layer of columnar cells of different heights and nuclei

  • for secretion and propulsion and may be ciliated

  • found in large glands, the male sperm duct and the respiratory tract (mainly the trachea)

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Stratified Squamous Epithelium
  • multiple layers of squamous cells on a basement membrane

  • basal cells are cube/columnar shaped and mitotically active

  • form protection against abrasion and damage for tissue underneath

  • cells change shape from upper (flatter squamous) to lower layers

  • found in all the places you can put a dick (includes esophagus)

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Stratified Cuboidal/Columnar Epithelium
  • two or more layers of cuboidal or columnar cells

  • used for secretion

  • found in male sperm duct, sweat and mammary glands, pharynx and male urethra

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Transitional Epithelium
  • appears to be stratified squamous cuboidal

  • surface cells are rounded/squamous

  • allow for stretch

  • lines the urinary tracts including the ureter, bladder and urethra

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Glandular Epithelia
  • cells specialized for secretion production

  • glands consist of one or more cells that secrete specific products (water, lipids or steroids)

  • classified by the cell number (unicellular or multicellular) and where the product is released (endocrine or exocrine)

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Exocrine Glands
  • cells that secrete their products into ducts

  • lead to a body surface or body cavity

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Unicellular Exocrine Gland
  • only have one goblet cell that secretes mucous

  • found in the lining of the digestive tract to reduce friction in the esophagus and large intestine

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Multicellular Exocrine Glands
  • divided into the duct region and secretory region

  • usually have connective tissue, nerves, blood vessels around the outside

  • produces substances and forms tubules for transport

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Multicellular Gland Classification
  • simple (unbranched) or compound (branched)

  • tubular (tublike), acrinar/alveolar (flasklike) or both

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Development of Exocrine Glands
- maintain its connection with the surface through ducts
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Endocrine Glands
  • do not have ducts and secrete directly into the extracellular space or blood vessel

  • travels to specific targets

  • cells of the adrenal gland secrete products directly into blood vessels

  • cells of the thymus gland secrete into spaces between cells

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Development of Endocrine Glands
- epithelium loses its ducts and secrete products directly into blood vessels
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41
Connective Tissue
  • provides support or integrity for other tissues/organs

  • most diverse abundant, widely distributed and structurally varied

  • connects one structure to another structure

  • includes tendons ligaments body fat, bones, blood and cartilage

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Functions of Connective Tissue
  • protection of tissues and organs against unnecessary movement

  • physical support (muscle attachments with bones)\

  • energy storage/insulation (adipose tissue)

  • transports substances (blood)

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Ground Substance of Connective Tissue
  • interstitial fluid that mixes with fibers to make up the extracellular matrix

  • a mixture of proteins to provide structural support along with carbohydrates

  • nutrients and other substances can pass between cells and blood vessels

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Fibers
  • 3 different kinds that provide support for connective tissue

  • may help determine structural properties of tissue

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Collagen
  • most common and strongest fiber

  • can resist being pulled apart

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Elastic
- fiber that can stretch and return to its original shape/length
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Reticular
- thin, branching collagen fibers that form extensive networks
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Cells in Connective Tissue
  • have active and less active states

  • developing are specific cell blasts

  • maturing are specific cell cytes

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Osteoblasts
- actively lay down minerals
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Osteocytes
- living but not active in the matrix
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Fibroblasts
  • very common cell of connective tissue

  • have secrete fibers

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Macrophages
- cleanup cells that engulf bacteria and cellular debris
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Plasma Cells
  • secrete antibodies

  • associated with the immune system

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Mast Cells
  • abundant by blood vessels

  • produced histamine that are involved in the inflammatory response

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Adipocytes
- cells of fat storage
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White Blood Cells
- not normally present but migrate in response to infections
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Areolar Loose Connective Tissue
  • most common, found under epithelial layers and surrounding organs

  • loosely-packed assembly of all fiber types and immune cells

  • cushions organs and contains key immune mediators to fight off infections

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Adipose Loose Connective Tissue
  • matrix surrounded by tightly packed adipocytes

  • insulates and protects organs while providing energy storage

  • found around organs and within the subcutaneous layer of skin

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Reticular Loose Connective Tissue
  • network of reticular fibers that are loosely organized

  • forms a flexible meshwork

  • supports tissues and immune cells

  • found in lymph nodes, bone marrow and splenic pulp

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Regular Dense Connective Tissue
  • fibroblasts embedded within a regularly parallel ordered assembly of collagen fibers

  • resists pulling from stress

  • attaches muscle to bone (tendons)

  • attaches bone to bone (ligaments)

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Irregular Dense Connective Tissue
  • irregularly arranged collagen fibers with fibroblasts embedded within

  • resists force from multiple directions

  • found in the dermis, joint capsules and underlying epithelial linings including the digestive tract

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Elastic Dense Connective Tissue
  • dense regular connective tissue enriched with ordered arrangements of elastin fiber

  • allows for stretch and recoil of tissue

  • important in blood and air

  • found in the walls of arteries and bronchial tubes and in some ligaments

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Cartilage
  • collagen and elastic fibers in a specialized matrix -provide support and withstand deformation

  • 3 types

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Chrondrocytes
- mature cells found in lacunae that are responsible for cartilage formation
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Hyaline Cartilage
  • most abundant and the weakest

  • found in developing bones

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Fibrocartilage
  • strongest and has lots of collagen

  • found in intervertebral discs

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Elastic Cartilage
  • contains lots of elastin to maintain shape

  • found in the ears

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Bone
  • similar to cartilage but has a solid matrix

  • osteocytes are formed in lacunae

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Blood
  • matrix of mostly water

  • has red and white blood cells ad platelets

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Lymph
  • matrix similar to blood with fewer proteins

  • cellular composition varies

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Muscle Tissue
  • generates mechanical force

  • three kinds

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Nervous Tissue
  • glial cells provide protection, nourishment and support to nerve cells

  • provide long-distance communication within the body

  • conducts the electrical impulses

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Epithelial Membranes
- have both epithelial and connective tissue
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Synovial Membranes
- only have connective tissue
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Cutaneous Membrane
  • type of epithelial membrane that covers the body (is skin)

  • keratinized, stratified squamous epithelium attached to a thick layer of connective tissue

  • exposed to air and dry

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Mucous Membranes
  • type of epithelial membrane that lines the passageways that open to the body surface

  • very important in defense by trapping particles and lubricates passages

  • may contain antibacterial agents

  • lines the digestive, respiratory and reproductive tracts

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Serous Membranes
  • type of epithelial membrane that lines the body cavity, not opening to the exterior

  • parietal layer is attached to the cavity

  • visceral layer is attached to the organs

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Synovial Membranes
  • where 2 bones come together

  • consists of connective tissue only

  • cells secrete synovial fluid that acts as a lubricant

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