Taguig Pateros ICU Drugs

HRZE Drugs

Rifampin, Isoniazid, pyrazinamide, and ethambutol

Therapeutic class is antituberculosis

Pharmacological class is semisynthetic rifamycin, isonicotinic derivative, nicotinic derivative, bacteriostatic.

HRZE Drugs side effects and nursing responsibilities

• Turn urine to red-orange color (Rifampin)

• Fatigue, epigastric distress, abdominal pain, hyperuricemia, pain in extremities.

• Malaise, peptic ulcer, Arthralgia, anorexia

• Joint pain

• Monitor hepatic function and uric acid levels.

• Monitor Vital signs

• Assist with ambulation if light-headedness or dizziness occurs.

• Monitor for orthostatic BP

• Take oral form on an empty stomach

• Avoid alcohol because it intensifies the hypotensive effect.

• Report signs/symptoms of hypotension, and angina.

• Warn patient that drowsiness may occur and that the drug can turn body fluids red-orange

• Advise the patient to report fever, loss of appetite, malaise, nausea, and dark urine.

• Monitor for unusual weakness and fatigue that might be due to anemia

Atorvastatin (Lipitor)

Therapeutic class is HMG-CoA reductase inhibitors (statins)

Pharmacological class is Antihyperlipidemic

Atorvastatin side effects and nursing responsibilities

• Headache

• Myalgia, rhabdomyolysis

• Follow special diet (LSLF; DM diet with SAP) 

• Do not take other medications without consulting the physician.

• Do not chew, crush, dissolve, or divide tablets.

• Report dark urine, muscle fatigue, and bone pain.

• Avoid excessive alcohol intake, large quantities of grapefruit products

N-Acetylcysteine (Parvolex)

Therapeutic Classification respiratory inhalant, intratracheal

Pharmacological Classification Mucolytic

N-Acetylcysteine side effects and nursing responsibilities

• Facial Edema

• bronchospasm

• wheezing

• nausea, vomiting

• Assess pretreatment respirations for rate, depth, and rhythm

• Monitor rate, depth, rhythm, type of respiration

• Auscultate lung sounds.

• Inform the client that adequate hydration is an important part of therapy.

Azythromycin (Zithromax)

Therapeutic Classification is macrolide

Pharmacological classification is antibiotic

Azythromycin Side effects and nursing responsibilities

• Abdominal pain

• Vomiting, nausea, diarrhea, and hepatotoxicity

• Give without regard to food

• Question for history of hepatitis or allergy to ​erythromycins.

• Assess for infection

• Monitor daily pattern of bowel activity and stool consistency.

• Monitor for diarrhea or oral mucosal changes

PIPTAZ

Therapeutic classification is Penicillin

Pharmacological classification is antibiotic

PIPTAZ Side effects and nursing responsibilities

• abdominal pain, dyspnea, constipation, insomnia

• Diarrhea, headache, rash, and anxiety

• Question for history of allergies especially to penicillins and cephalosporins.

• Monitor daily bowel activities and stool consistency

• Be alert for fever, vomiting, diarrhea, anal/genital pruritus, and oral mucosal changes.

Omperazole

Therapeutic classification is benzimidazole

Pharmacological classification is proton pump inhibitor

Omeprazole side effects and nursing responsibilities

• Headache, abdominal pain, asthenia

• upper respiratory tract infection, and cough

• Inform patient that the drug causes an increased risk of fractures and gastrointestinal infections.

• Inform patient to report black tarry stools, and diarrhea and to avoid alcohol.

Paracetamol

Therapeutic Classification is NSAIDs

Pharmacological Classification is Analgesic

Paracetamol side effects and nursing responsibilities

• Nausea, fatigue, diaphoresis, vomiting, and right upper quadrant

• Assess onset, type, location, and duration of pain.

• Assess liver function test in paints with chronic usage or history of alcohol abuse.

• Instruct patient and family to report severe or recurring pain may indicate serious illness.

Tramadol

Therapeutic classification is Centrally acting synthetic opioid

Pharmacological classification is Analgesic

Tramadol Side effects and nursing responsibilities

• Tremors, asthenia, constipation, headache, drowsiness

• May cause seizure activity at usual

• Assess onset, type, location, duration of pain

• Monitor heart rate, BP. Assist with ambulation if dizziness, vertigo occurs

• Administer with food to prevent GI upset

• Measure weight regularly to monitor fluid changes.

• Palpate bladder for urinary retention

Telmisartan

Therapeutic class is Angiotensin II receptor antagonist

Pharmacological class is antihypertensive

Telmisartan Side effects and Nursing responsibilities

• Upper respiratory tract infection

• Leg pain, fatigue, myalgia, and cough.

• Obtain BP, and heart rate immediately before each dose

• Tell patient to report unexplained muscle pain, tenderness, or weakness.

Celecoxib

Therapeutic Classification is NSAIDs

Pharmacological Classification is Cyclooxygenase-2 inhibitors

Celecoxib

• Upper respiratory tract infection, Insomnia, abdominal pain.

• Monitor BP and renal and liver function

• Assess onset, type, location, duration of pain/inflammation. Inspect appearance of affected joints for immobility

• Watch for signs of liver toxicity

• Monitor renal function

Allopurinol

Therapeutic classification is xanthine oxidase inhibitor

Pharmacological classification antigout agent

Allopurinol side effects and nursing responsibilities

• joint pain, nausea, malaise

• Give after meals with plenty of fluids

• Monitor I & O

• Output should be around 2 L

• Inform patient to drink at least 2500 ml - 3000 ml of fluid daily while taking meds

• Avoid alcohol

Pregabalin

The therapeutic class is GABA-analogue

The pharmacological class is antineuralgic

Pregabalin side effects and nursing responsibilities

• Dizziness and drowsiness

• Constipation and tremors

• Assess onset, type, location, and duration of pain.

• Assess for clinical improvement and record onset of relief of pain.

• Tell patient and family not to stop taking the drug abruptly.

• Avoid alcohol.