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Arteries
Blood vessels that carry blood away from the heart toward capillaries.
Arterioles
Small branches of arteries that lead to capillary beds and regulate blood flow.
Capillaries
Microscopic blood vessels where exchange of gases, nutrients, and wastes occurs between blood and tissues.
Veins
Blood vessels that carry blood toward the heart from capillaries.
Venules
Small vessels that gather blood from capillaries into veins.
Atria
The heart's upper chambers that receive blood returning to the heart.
Ventricles
The heart's lower chambers that pump blood out to the body or lungs.
Pulmonary circuit
Carries blood between the heart and lungs for gas exchange.
Systemic circuit
Carries blood between the heart and the rest of the body.
Systole
Contraction phase of the cardiac cycle, when blood is pumped out.
Diastole
Relaxation phase of the cardiac cycle, when the heart fills with blood.
Sinoatrial (SA) node
Pacemaker cells in the right atrium that set the heart's rhythm.
Atrioventricular (AV) node
Relays signals from the SA node to the ventricles, causing them to contract.
Low-density lipoprotein (LDL)
"Bad" cholesterol; delivers cholesterol to cells and can form plaques in arteries.
High-density lipoprotein (HDL)
"Good" cholesterol; removes excess cholesterol and returns it to the liver.
Ventilation
The process of moving air or water over a respiratory surface.
Countercurrent exchange
Opposite flow of fluids (e.g., blood and water in fish gills) that maximizes diffusion efficiency.
Larynx
Voice box; part of the airway containing the vocal cords.
Trachea
Windpipe; conducts air from the larynx into the bronchi.
Bronchi
Two main branches leading from the trachea into each lung.
Bronchioles
Smaller branching tubes within the lungs that lead to alveoli.
Alveoli
Tiny air sacs at the end of bronchioles; primary sites of gas exchange in mammals.
Diaphragm
Sheet of muscle at the base of the lungs that drives inhalation and exhalation.
Hemoglobin
Iron-containing protein in red blood cells that binds oxygen and facilitates gas transport.
Bohr shift
The effect of lowered pH (from CO₂ accumulation) decreasing hemoglobin's affinity for O₂, enhancing oxygen delivery to tissues.
Hemolymph
Circulatory fluid in animals with open circulatory systems (combines blood and interstitial fluid).
Tracheal system
Network of air tubes in insects that directly deliver oxygen to tissues.
Circulatory fluid
e.g., blood or hemolymph
Set of interconnecting vessels
Network of tubes that transport circulatory fluid
Muscular pump
Heart that moves the circulatory fluid
Open circulatory system
Circulatory fluid (hemolymph) bathes organs directly; found in arthropods and mollusks.
Closed circulatory system
Blood is confined to vessels, distinct from interstitial fluid; found in annelids, cephalopods, and vertebrates.
Single circulation
Blood passes through the heart once per circuit; characteristic of fish.
Double circulation
Blood passes through the heart twice (once for lungs, once for body); seen in amphibians, reptiles, and mammals.
4-chambered heart
Heart structure in mammals that separates oxygenated and deoxygenated blood completely.
Blood flow pathway in mammals
Right atrium → right ventricle → pulmonary arteries → lungs → pulmonary veins → left atrium → left ventricle → aorta → body tissues → vena cavae → right atrium
SA node
Initiates heartbeat and causes atria to contract.
AV node
Delays signal briefly before it travels down bundle branches and Purkinje fibers to cause ventricles to contract.
Velocity in capillaries
Slowest in capillaries for exchange.
Pressure in circulatory system
Highest in arteries, lowest in veins.
Plasma
Fluid matrix with nutrients, ions, proteins.
Erythrocytes (RBCs)
Transport O₂ via hemoglobin.
Leukocytes (WBCs)
Provide immune defense.
Platelets
Involved in blood clotting.
Atherosclerosis
Plaque buildup (LDL cholesterol) that narrows arteries.
Hypertension
High blood pressure that damages vessels.
Risk factors for cardiovascular disease
High LDL, low HDL, smoking, inactivity, poor diet, genetics.
Respiratory surfaces in animals
Skin (earthworms, amphibians), gills (fish, aquatic invertebrates), tracheal systems (insects), lungs (terrestrial vertebrates).
Positive pressure breathing
Air is pushed into lungs by muscular contraction; characteristic of amphibians.
Negative pressure breathing
Air is pulled in as diaphragm expands thoracic cavity; characteristic of mammals.
Hemocyanin
Copper-based pigment that carries O₂ in arthropods/mollusks; increases oxygen transport efficiency in the blood.