G-Protein Activation
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10 Terms
What is the 1st step?
1st messenger binds plasma membrane receptor
What step happens after 1st messenger binds plasma membrane receptor?
G-protein binds receptor
What happens after G-protein binds receptor?
GDP kicked off ; GTP binds
What is GTP?
Energy Molecule
What happens after GDP is kicked off ; GTP binds?
Alpha-GTP leaves ; Beta and gamma leave
What happens after alpha-GTP leaves ; Beta and gamma leave?
Alpha-GTP binds a membrane protein : AC (Adenylate Cyclase) or PLC (Phospholipase C)
What happens after Alpha-GTP binds a membrane protein : AC (Adenylate Cyclase) or PLC (Phospholipase C)?
AC converts ATP to cAMP
Is cAMP a 1st or 2nd messenger?
2nd
What happens after AC converts ATP to cAMP?
Protein Kinase A (PKA) is activated by cAMP
What happens after Protein Kinase A (PKA) is activated by cAMP?
PKA phosphorylates ; (Typically turns protein on or off)
Note 
Flashcards (37)