Allergic Response Drugs (Pharm 1)
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Last updated 6:43 PM on 3/15/26
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32 Terms
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H1 Receptor Antagonists Example:
diphenhydramine (Benadryl)
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H1 Receptor Antagonists Action:
Blocks histamine receptor sites
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H1 Receptor Antagonists Use:
Most hypersensitivity reactions. Caution for use in children. Do not give for children under 6
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H1 Receptor Antagonists AE:
CNS depression, neuro impairment, anxiety, agitation, anticholergenic effects
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Other H1 Receptor Antagonists Ex:
hydroxyzine pamoate (Promethazine)
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Other H1 Receptor Antagonists Use:
N/V, sedation. Not a first line tx
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Other H1 Receptor Antagonists AE:
Most common in kids, CNS effects, hallucinations
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Second Gen H1 Receptor Antagonists Ex:
cetirizine (Zyrtec), loratadine (Claritin)
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Second Gen H1 Receptor Antagonists Action:
Bind w/ peripheral receptors. Lasts a long time = has a long half life
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Second Gen H1 Receptor Antagonists Use:
Seasonal allergies
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Second Gen H1 Receptor Antagonists AE:
N/V, fatigue, drowsiness
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Third Gen H1 Receptor Antagonists Ex:
fexofenadine (Allegra)
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Third Gen H1 Receptor Antagonists Use:
Seasonal allergies, congestion
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Nasal Decongestants Ex:
pseudoephedrine (Sudafed)
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Nasal Decongestants Action:
vasoconstriction (due to release of NE)
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Nasal Decongestants Use:
allergies, cough, cold
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Nasal Decongestants Contraindications:
don't use on kids, or with dry eyes. Common ingredient in meth making
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Antitussives Ex:
dextromethorphan (Delsym) non-narc, non-drowsy
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Antitussives Action:
cough suppressant
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Antitussives Use:
When cough is so bad it interferes with sleep
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Antitussives: Indications:
do NOT dilute, avoid food/water w/in 30 minutes of admin
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Other Common Drugs (2)
benzonatate (Tessalon Pearls). Use: cough suppressant-needs prescription
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oxymetazoline (Afrin). Use: decongestant nasal spray-commonly abused
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Expectorants Ex:
guaifenesin (Mucinex)
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Expectorants Action:
Decrease mucus secretion viscosity
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Expectorants Use:
Productive cough, pneumonia, bronchitis
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Expectorants SE:
rash, HA, N/V
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Herbal Remedies Ex:
zinc sulfate (Zicam), Vit C, Echinacea
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Herbal Remedies- Zinc
decreases length and severity of colds. must be balanced with copper
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Herbal Remedies- Vit C
reduces incidence of colds and flu
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Herbal Remedies- Echinacea
A flower that boosts the immune system to fight the common cold and flu. unknown action, just works
