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A set of fill-in-the-blank flashcards covering core terminology, anatomy, physiology, and biochemistry of the digestive system to aid exam preparation.
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The first of the six general functions of the digestive system is __.
ingestion
In the digestive system, coordinated muscular contractions that move material through the tract are called __.
motility (peristalsis and mixing)
The release of water, acid, buffers, and enzymes into the lumen of the GI tract is known as __.
secretion
The physical and chemical processes that break food into smaller molecules are collectively called __.
digestion
The movement of digested substances from the GI lumen into blood or lymph is __.
absorption
The elimination of indigestible residues from the body is termed __.
defecation (elimination)
The six organs that form the gastrointestinal (GI) tract are the oral cavity, pharynx, esophagus, stomach, __, and large intestine.
small intestine
The four tunics of the GI wall from deep to superficial are mucosa, __, muscularis, and serosa/adventitia.
submucosa
Peristalsis and segmentation are produced by the __ tunic of the GI tract.
muscularis
The nerve plexus located in the submucosa is the __ plexus.
submucosal (Meissner)
The myenteric plexus is located between the layers of the __ tunic.
muscularis
Organs that are completely surrounded by peritoneum and suspended by mesenteries are called __ organs.
intraperitoneal
Gastrin, secretin, and cholecystokinin (CCK) are three major __ that regulate digestion.
hormones
Mechanical digestion breaks food into smaller pieces, whereas __ digestion uses enzymes to break chemical bonds.
chemical
The anterior chamber of the upper GI tract that contains the tongue and teeth is the __.
oral cavity (mouth)
The three pairs of major salivary glands are the parotid, __, and sublingual glands.
submandibular
Chewing, or __, increases the surface area of food for enzymatic attack.
mastication
Primary (deciduous) teeth begin to erupt around __ months of age.
6
During swallowing, elevation of the soft palate and uvula blocks the __ to prevent food from entering the nasal cavity.
nasopharynx
The stomach cell that secretes hydrochloric acid and intrinsic factor is the __ cell.
parietal
An inactive digestive enzyme precursor is called a __.
zymogen (proenzyme)
Food in the stomach triggers the __ phase, a neural reflex that increases gastric motility and secretion.
gastric
The three regions of the small intestine from proximal to distal are the duodenum, __, and ileum.
jejunum
Brunner’s glands, found in the submucosa of the duodenum, secrete __ mucus.
alkaline (bicarbonate-rich)
Segmenting contractions in the small intestine that mix chyme with digestive juices are called __.
segmentation
The liver, gallbladder, and __ are the three accessory organs that empty secretions into the duodenum.
pancreas
Within a hepatic lobule, deoxygenated nutrient-rich blood from the portal vein mixes with oxygenated blood from the hepatic artery in the __.
hepatic sinusoids
The cecum, colon, and rectum are the three major regions of the __.
large intestine
Teniae coli, haustra, and abundant goblet cells are distinguishing histologic features of the __.
large intestine (colon)
Circular folds, villi, and __ are the three structures that greatly increase surface area in the small intestine.
microvilli
Stomach, jejunum, ileum, transverse colon, and sigmoid colon are examples of __ organs.
intraperitoneal
Pancreatic juice contains digestive enzymes and bicarbonate to __ acidic chyme entering the duodenum.
neutralize
Chyme passes from the ascending colon to the transverse colon at the __ colic flexure.
right (hepatic)
Glucose, gas production, and vitamin K synthesis in the colon are all results of __ action.
bacterial
Monosaccharides, disaccharides, and polysaccharides are the three major classes of __.
carbohydrates
Carbohydrate digestion begins in the mouth with the action of __ amylase.
salivary
In the small intestine, brush-border enzymes such as maltase and lactase complete the digestion of __ to monosaccharides.
disaccharides
The enzyme that initiates protein digestion in the stomach is __.
pepsin
Proteolytic enzymes are synthesized in inactive forms to prevent __ of the producing cells.
autodigestion (self-digestion)
Trypsin, chymotrypsin, and carboxypeptidase complete most protein digestion in the __ intestine.
small
Bile salts emulsify fats by forming tiny lipid droplets called __.
micelles
Inside enterocytes, absorbed fatty acids and monoglycerides are recombined to triglycerides and packaged into __.
chylomicrons
Pancreatic nucleases and brush-border enzymes break down DNA and RNA into nitrogenous bases, sugars, and __ groups.
phosphate
Short autonomic reflexes of the digestive tract that occur entirely within the enteric nervous system are called __ reflexes.
local (short)
Complete starch digestion requires salivary amylase, pancreatic amylase, and brush-border enzymes such as __.
maltase (also dextrinase, glucoamylase, sucrase, lactase)
Enterokinase (enteropeptidase) activates trypsinogen to trypsin, and trypsin then activates other pancreatic __.
zymogens (e.g., chymotrypsinogen, procarboxypeptidase)
The primary action of bile salts in lipid digestion is to __ large lipid droplets, increasing their surface area for enzyme attack.
emulsify