Cell Junctions and Cell Adhesion Vocabulary

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Flashcards on Cell Junctions and Cell Adhesion

Medicine

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22 Terms

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Tight Junction

Seals the gap between epithelial cells.

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Adherens Junction

Connects actin filament bundle in one cell with that in the next cell.

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Desmosome

Connects intermediate filaments in one cell to those in the next cell.

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Gap Junction

Allows the passage of small water-soluble molecules from cell to cell.

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Actin-linked cell-matrix junction

Anchors actin filaments in cell to extracellular matrix.

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Hemidesmosome

Anchors intermediate filaments in a cell to extracellular matrix.

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Adherens junctions

Cell-cell.

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Desmosomes

Cell-cell. Strength, durability, signaling.

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Hemidesmosomes

Cell-matrix Shape, rigidity, signaling.

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Focal, fibrillar, and 3-D adhesions

Cell-matrix Shape, signaling, force transmission, cell movement.

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Tight junctions

Cell-cell Controlling solute flow, signaling.

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Gap junctions

Cell-cell Communication, small-molecule transport between cells.

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Plasmodesmata

Cell-cell Communication, molecule transport between cells.

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Cell Adhesion Molecules (CAM)

Proteins on the cell surface involved in cell-cell interaction.

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Cadherins

A class of calcium-dependent adhesion molecules primarily composing adherens junctions.

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Adherens Junctions and Desmosomes

Adhesive structures that maintain the physical integrity of cells within tissues.

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Adherens junctions

A type of cell-cell adhesion structure where the transmembrane protein cadherin indirectly connects to the actin cytoskeleton within the cell.

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Desmosomes

Provide mechanical strength, allowing cells and tissues to maintain their integrity under high stress.

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Tight Junctions

Act as selective permeation barriers, separating the tissue penetrating fluid on their basal side from the fluid with a different chemical composition on their apical side.

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Gap Junctions

Links that connect neighboring cell cytoplasms.

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Selectins

Cell surface carbohydrate-binding proteins (lectins) that mediate a variety of transient cell-cell adhesion interactions in the bloodstream.

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Integrins

The main cell surface receptors responsible for the attachment of cells to the ECM.