Chapter 14 - Type III Allergies

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5 Terms

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Type III Hypersensitivities

Immune Complex Reactions; Reaction of soluble antigen (not attached to cell surface) with antibody, and deposition of these complexes in various tissues in the body

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immune complex reaction (type III)

produces free-floating complexes that are deposited into tissues

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arthus reaction and serum sickness (type III)

are associated with passive immunization (providing Ig from healthy patients to recipients)

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antibodies, neutrophils

  • In immune complex disease, large quantities of _______ are produced in response to large amounts of antigen

  • Upon second exposure antigen-antibody complexes form and recruit complement and _______ to area

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immune complex disease

  • _______ _________ ________ - complexes deposited into basement membranes of epithelial tissues:

  • neutrophils release granules that digest tissues and cause destructive inflammation to damage endothelial cells