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Cancer Overview
Second leading cause of death worldwide; 1.9 million new cases and 610,000 deaths annually; 68% of new cases survive at least 5 years.
What is Cancer?
Disease of uncontrolled cell growth forming tumors (neoplasms). Types include carcinoma (organs/skin), melanoma (pigment cells), lymphoma (lymphatic system), sarcoma (muscle/bone), and leukemia (blood).
Common Cancer Types
Skin Cancer (3.5M cases/year); Prostate Cancer (221K, 100% early survival); Breast Cancer (232K, 99% early, 85% spread); Lung Cancer (221K, 54% localized, 17% spread); Colorectal Cancer (132K, 90% early, 65% overall).
Cancer Physiology
Carcinogens cause abnormal cell growth; uncontrolled cells form neoplasms, which can spread via metastasis to other organs.
Benign vs. Malignant Neoplasms
Benign = harmless; malignant = harmful. Malignant tumors steal nutrients, block organ function, and can cause death or infection.
Cancer Risk Factors
UV exposure, hazardous chemicals, genetic vulnerabilities, age, smoking, poor diet, obesity, and chronic stress.
Cancer Treatment Overview
Early detection increases survival. Goal = remove all neoplasms or achieve remission. Common treatments: surgery, radiation, chemotherapy.
Surgery (Cancer Treatment)
Removes cancerous tissue; often combined with radiation or chemo. Not always possible if cancer has spread widely.
Radiation Therapy
High-dose radiation destroys cancerous cells; malignant cells can’t repair themselves effectively. Delivered externally or via radioactive injections.
Chemotherapy
Uses powerful drugs to kill rapidly dividing cells throughout the body; side effects include hair loss, fatigue, nausea, and weakened immunity.
Psychosocial Effects of Cancer Treatment
Emotional and physical side effects—fatigue, nausea, hair loss, sexual dysfunction, and fear of recurrence. Patients often show strong treatment adherence.
Psychosocial Interventions for Cancer
Counseling for adjustment and emotional regulation; promote healthy behaviors (e.g., smoking cessation); support from family improves outcomes.
HIV / AIDS Overview
HIV (Human Immunodeficiency Virus) attacks CD4 T-cells; if untreated, progresses to AIDS (Acquired Immunodeficiency Syndrome). Weakens immune system, causing vulnerability to infections.
HIV / AIDS Statistics
37 million worldwide; highest rates among 20–29-year-olds; 3× higher in men; 1.7 million new infections and 700,000 deaths annually.
HIV Physiology
Virus infects CD4 T-cells, replicates, and destroys them. Weakens immune system over time; progression to AIDS can take years, leading to fever, fatigue, diarrhea, and swollen lymph glands.
HIV Transmission Routes
Unprotected sex, shared needles, mother-to-child transmission, or (rarely) blood transfusions. Not transmitted through casual contact, hugging, or insects.
HIV Risk Factors
Influenced by biological, social, and economic conditions; stigma and lack of awareness increase spread.
HIV / AIDS Treatment
Antiretroviral Therapy (ART) suppresses viral replication and maintains immune function. Goal: U=U (Undetectable = Untransmittable). Requires lifelong adherence.
HIV Prevention
Use of PrEP, PEP, condoms, needle exchange programs, and regular testing to prevent infection.
Physical Effects of HIV / AIDS
Fatigue, fever, weight loss, infections, and neurological symptoms.
Emotional and Family Effects
Fear, anxiety, depression, and stigma; caregiver stress, financial strain, and relational challenges.
Psychosocial Factors (HIV / AIDS)
Stigma, discrimination, and fear of disclosure reduce testing and adherence. Negative emotions (hopelessness, isolation) can speed disease progression.
Psychosocial Interventions (HIV / AIDS)
Counseling for coping and adherence; support groups to reduce stigma; mental health and substance use services; education to counter misinformation.
Key Message
With treatment and support, individuals with HIV can live long, healthy lives.