BIOL 23373 - General Genetics Lecture 26: Gene Interactions II

Flashcards covering key concepts related to gene interactions and epistasis from the genetics lecture.

Epistasis

Gene interactions in which the alleles of one gene modify or prevent expression of alleles of another gene.

Epistatic gene

A gene that modifies the expression of another gene (the hypostatic gene).

Hypostatic gene

A gene whose expression is modified or suppressed by another gene (the epistatic gene).

Complementary gene interaction

A type of gene interaction where two genes work together to produce a single trait, resulting in a 9:7 phenotypic ratio.

Duplicate gene action

A situation where two genes duplicate each other's effects, leading to a 15:1 phenotypic ratio.

Recessive epistasis

A gene interaction where a homozygous recessive genotype at one locus masks the expression of alleles at another locus, giving a 9:3:4 ratio.

Dominant epistasis

A gene interaction where a dominant allele at one locus masks the expression of alleles at a second locus, producing a 12:3:1 ratio.

Dominant suppression

A gene interaction where a dominant allele at one locus suppresses the expression of a dominant allele at another, resulting in a 13:3 ratio.

Bombay phenotype

A condition in which individuals with a homozygous recessive genotype at the FUT1 gene express type O blood, masking the effects of I gene alleles.

FUT1 gene

A gene required for the synthesis of H substance on red blood cells; mutations can lead to type O blood regardless of I gene alleles.