Chemistry - Synthetic routes

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38 Terms

1

Alkene → Haloalkane

Hydrogen halide

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2

Alkene → Alkane

Hydrogen

Nickel catalyst

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3

Alkene → Alcohol

Steam

H3PO4 Catalyst

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4

Alkene → Polymer

High pressure

High temperature

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5

Alkane → Haloalkane

Halogen

UV light

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6

Alcohol → Alkene

Conc. H2SO4/H3PO4

Heat

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7

Alcohol → Haloalkane

Sodium halide

H2SO4

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8

Haloalkane → Alcohol

NaOH Reflux

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9

Alcohol → Aldehyde

K2Cr2O7/H2SO4

Distil

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10

Alcohol → Ketone

K2Cr2O7/H2SO4

Reflux

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11

Alcohol → Ester

Carboxylic acid

conc. H2SO4 catalyst

or Acid anhydride or Acyl chloride

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12

Aldehyde → Carboxylic acid

K2Cr2O7/H2SO4

Reflux

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13

Aldehyde → Hydroxynitrile

NaCN/H+

(HCN)

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14

Ketone → Hydroxynitrile

NaCN/H+

(HCN)

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15

Ketone → Alcohol

NaBH4/H2O

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16

Aldehyde → Alcohol

NaBH4/H2O

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17

Haloalkane → Nitrile

NaCN Ethanol Reflux

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18

Haloalkane → Amine

NH3

Ethanol (in excess)

Heat

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19

Nitrile → Amine

Hydrogen

Nickel Catalyst

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20

Nitrile → Carboxylic acid

H2O/HCl

Heat

Reflux

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21

1⁰ Amine → 2⁰ amine

Haloalkane Ethanol

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22

Amine → 2⁰ amide

acyl chloride

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23

Acyl chloride → 1⁰ amide

NH3

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24

Acyl chloride → 2⁰ amide

1° amine

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25

Acyl chloride → Carboxylic acid

H2O

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26

Carboxylic acid → Acyl chloride`

SOCl2

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27

Acyl chloride → Ester

Alcohol

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28

Ester →Carboxylic acid

Dilute acid/alkali Heat Reflux

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29

Carboxylic acid → Ester

Alcohol conc. H2SO4 catalyst

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30

Benzene → Halobenzene

Halogen

Halogen carrier catalyst (AlCl₃)

Heat

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31

Benzene → Alkyl benzene

Haloalkane

Halogen carrier catalyst (AlCl3)

Reflux

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32

Benzene →Nitrobenzene

Conc. HNO3

Conc. H2SO4

under 50°C

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33

Nitrobenzene →Phenylamine

  1. Sn Conc. HCl Reflux

  2. NaOH

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34

Benzene → Phenylketone

Acyl chloride

Halogen carrier catalyst (AlCl3)

Reflux

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35

Phenol → Sodium phenoxide

NaOH

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36

Phenol → Phenyl Ester

Acyl Chloride

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37

Phenol →2-Nitrophenol/4-Nitrophenol

Dilute HNO3

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38

Phenol →2,4,6-tribromophenol

Bromine water

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