Chemistry - Synthetic routes

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38 Terms

1
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Alkene → Haloalkane
Hydrogen halide
2
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Alkene → Alkane
Hydrogen

Nickel catalyst
3
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Alkene → Alcohol
Steam

H3PO4 Catalyst
4
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Alkene → Polymer
High pressure

High temperature
5
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Alkane → Haloalkane
Halogen

UV light
6
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Alcohol → Alkene
Conc. H2SO4/H3PO4

Heat
7
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Alcohol → Haloalkane
Sodium halide

H2SO4
8
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Haloalkane → Alcohol
NaOH
Reflux
9
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Alcohol → Aldehyde
K2Cr2O7/H2SO4

Distil
10
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Alcohol → Ketone
K2Cr2O7/H2SO4

Reflux
11
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Alcohol → Ester
Carboxylic acid

conc. H2SO4 catalyst

or Acid anhydride or Acyl chloride
12
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Aldehyde → Carboxylic acid
K2Cr2O7/H2SO4

Reflux
13
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Aldehyde → Hydroxynitrile
NaCN/H+

(HCN)
14
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Ketone → Hydroxynitrile
NaCN/H+

(HCN)
15
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Ketone → Alcohol
NaBH4/H2O
16
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Aldehyde → Alcohol
NaBH4/H2O
17
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Haloalkane → Nitrile
NaCN
Ethanol
Reflux
18
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Haloalkane → Amine
NH3

Ethanol (in excess)

Heat
19
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Nitrile → Amine
Hydrogen

Nickel Catalyst
20
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Nitrile → Carboxylic acid
H2O/HCl

Heat 

Reflux
21
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1⁰ Amine → 2⁰ amine
Haloalkane
Ethanol
22
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Amine → 2⁰ amide
acyl chloride
23
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Acyl chloride → 1⁰ amide
NH3
24
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Acyl chloride → 2⁰ amide
1° amine
25
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Acyl chloride → Carboxylic acid
H2O
26
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Carboxylic acid → Acyl chloride\`
SOCl2
27
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Acyl chloride → Ester
Alcohol
28
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Ester →Carboxylic acid
Dilute acid/alkali
Heat
Reflux
29
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Carboxylic acid → Ester
Alcohol conc. H2SO4 catalyst
30
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Benzene → Halobenzene
Halogen

Halogen carrier catalyst (AlCl₃)

Heat
31
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Benzene → Alkyl benzene
Haloalkane

Halogen carrier catalyst (AlCl3)

Reflux
32
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Benzene →Nitrobenzene
Conc. HNO3

Conc. H2SO4

under 50°C
33
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Nitrobenzene →Phenylamine
1) Sn
Conc. HCl
Reflux
2) NaOH
34
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Benzene → Phenylketone
Acyl chloride

Halogen carrier catalyst (AlCl3)

Reflux
35
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Phenol → Sodium phenoxide
NaOH
36
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Phenol → Phenyl Ester
Acyl Chloride
37
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Phenol →2-Nitrophenol/4-Nitrophenol
Dilute HNO3
38
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Phenol →2,4,6-tribromophenol
Bromine water