Chemistry - Synthetic routes

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38 Terms

1
Alkene → Haloalkane
Hydrogen halide
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2
Alkene → Alkane
Hydrogen

Nickel catalyst
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3
Alkene → Alcohol
Steam

H3PO4 Catalyst
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4
Alkene → Polymer
High pressure

High temperature
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5
Alkane → Haloalkane
Halogen

UV light
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6
Alcohol → Alkene
Conc. H2SO4/H3PO4

Heat
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7
Alcohol → Haloalkane
Sodium halide

H2SO4
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8
Haloalkane → Alcohol
NaOH
Reflux
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9
Alcohol → Aldehyde
K2Cr2O7/H2SO4

Distil
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10
Alcohol → Ketone
K2Cr2O7/H2SO4

Reflux
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11
Alcohol → Ester
Carboxylic acid

conc. H2SO4 catalyst

or Acid anhydride or Acyl chloride
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12
Aldehyde → Carboxylic acid
K2Cr2O7/H2SO4

Reflux
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13
Aldehyde → Hydroxynitrile
NaCN/H+

(HCN)
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14
Ketone → Hydroxynitrile
NaCN/H+

(HCN)
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15
Ketone → Alcohol
NaBH4/H2O
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16
Aldehyde → Alcohol
NaBH4/H2O
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17
Haloalkane → Nitrile
NaCN
Ethanol
Reflux
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18
Haloalkane → Amine
NH3

Ethanol (in excess)

Heat
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19
Nitrile → Amine
Hydrogen

Nickel Catalyst
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20
Nitrile → Carboxylic acid
H2O/HCl

Heat 

Reflux
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21
1⁰ Amine → 2⁰ amine
Haloalkane
Ethanol
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22
Amine → 2⁰ amide
acyl chloride
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23
Acyl chloride → 1⁰ amide
NH3
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24
Acyl chloride → 2⁰ amide
1° amine
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25
Acyl chloride → Carboxylic acid
H2O
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26
Carboxylic acid → Acyl chloride\`
SOCl2
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27
Acyl chloride → Ester
Alcohol
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28
Ester →Carboxylic acid
Dilute acid/alkali
Heat
Reflux
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29
Carboxylic acid → Ester
Alcohol conc. H2SO4 catalyst
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30
Benzene → Halobenzene
Halogen

Halogen carrier catalyst (AlCl₃)

Heat
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31
Benzene → Alkyl benzene
Haloalkane

Halogen carrier catalyst (AlCl3)

Reflux
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32
Benzene →Nitrobenzene
Conc. HNO3

Conc. H2SO4

under 50°C
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33
Nitrobenzene →Phenylamine
  1. Sn Conc. HCl Reflux

  2. NaOH

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34
Benzene → Phenylketone
Acyl chloride

Halogen carrier catalyst (AlCl3)

Reflux
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35
Phenol → Sodium phenoxide
NaOH
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36
Phenol → Phenyl Ester
Acyl Chloride
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37
Phenol →2-Nitrophenol/4-Nitrophenol
Dilute HNO3
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38
Phenol →2,4,6-tribromophenol
Bromine water
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