Innate Immune System Flashcards

Flashcards about the innate immune system. The flashcards are in a vocabulary style.

Innate Immunity

Rapid and short-lived immune response that is repetitive and interactive, but non-reactive to the host.

Pattern Recognition Receptors (PRRs)

Receptors on innate immune cells, epithelial, and endothelial cells that recognize patterns on pathogens.

Pathogen-Associated Molecular Patterns (PAMPs)

Molecules present on the surface of microbes that are recognized by PRRs.

Damage-Associated Molecular Patterns (DAMPs)

Molecules released from damaged host cells that are recognized by PRRs.

Main Types of Innate Immune Cells

Neutrophils, basophils, eosinophils, and monocytes/macrophages.

Toll-like receptors (TLRs)

Receptors discovered that can detect different types of patterns including bacterial lipopolyptides, peptoglycans, polysaccharides, flagellin parts.

NOD-like receptors

Free floating receptors within the cell cytoplasm space.

Complements

Series of proteins made by the liver that are able to bind to microbes and have a cascade effect that ends up activating other types of immune cells.

Phagocytosis

The process of a cell ingesting and destroying pathogens or cellular debris.

Dendritic Cells

Professional antigen-presenting cells that bridge the innate and adaptive immune systems.