Chapter 7: Blood Platelets and Blood Plasma

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22 Terms

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forming a platelet plus at the site of an injury

Platelets help control bleeding by:

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vasoconstriction

What does the release of serotonin from blood platelets trigger?

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platelet-derived growth factor

Promotes the repair of damaged blood vessel walls

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fibrinogen

Which plasma protein is necessary for blood clotting?

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platelet plug formation

What event is triggered by platelet activation upon contacting exposed collagen fibers? 

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coagulation

What event is triggered by fibrinogen being converted into fibrin?

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blood clot; coagulation

A network of fibrin threads that entangles platelets is called ______ and is a direct product of _______.

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extrinsic

Tissue thromboplastin is initiated by the ______ mechanism.

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intrinsic 

Hageman factor is initiated by the ______ mechanism. 

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smooth lining of blood vessel

prevents platelet adhesion

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antithrombin in plasma

inactivates thrombin and other clotting factors

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heparin from basophils

enhances antithrombin

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extrinsic mechanism

Which pathway is triggered by damage to vessels/tissue?

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intrinsic mechanism

Which pathway is triggered by blood contacting connective tissue?

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positive

Blood coagulation is a _______ feedback mechanism.

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fibrinogen converted into fibrin

What forms the actual blood clot?

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hemostasis

The process that stops bleeding when a blood vessel is injured

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collagen

To form a platelet plug, platelets stick to exposed ______ in the vessel wall.

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fragments; megakaryoblasts

Platelets are ________ of cells, derived from the shattering of _________.

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calcium (Ca2+)

essential for activation of several clotting factors

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plasmin 

breaks down fibrin 

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blood clot

A network of threadlike fibrin fibers, trapped blood cells, platelets and fluid