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When does the GI tract fully mature?
Age 2
What is the most common entry for infectious pathogens?
The mouth, because it is highly vascular
What is the Lower Esophageal Sphinter?
Prevents regurgitation of stomach contents up into esophagus or oral cavity.
When does esophagus develop?
1 month
What happens with narrowing of the esophagus?
Dysphagia
Stomach Capacity of a Newborn?
10-20 mL
Stomach Capacity of a 2 month?
200mL but can’t tolerate 200mL
Stomach Capacity of a 16 year old?
1,500 mL
Stomach Capacity of an adult?
2k-3k mL
When does Hydrochloric acid form?
6 months (at adult level)
How long is a full-term infant’s small intestine?
250 cm / 8 ft
How long is an adult’s small intestine?
600 cm / 20 ft
What is easily palpable at birth?
The liver, it is large compared to the rest of the body
Why do Infants/Children require larger fluid intake?
They excrete a greater amount of fluid leaving thema t risk of fluid loss with illness.
What does having a larger body surface for infants a bad thing?
Increased risk of insensible (unmeasurable) fluid loss.
What does having a higher Basal Metabolic rate mean?
Increase risk of insensible fluid loss and need for water (for excretory functions)
What do inspect for GI System?
Color, Hydration Status, Abdominal Size/Shape, Mental Status
Describe Inspection for Color?
Check for Pallor → anemia/dehydration
Icteric Sclerae (yellow eyes) or Jaundiced skin → inc bilirubin lvls
related to liver dysfunction
Describe Inspection of Hydration Status
Decreased turgor or tenting → dehydration
Absence of tears while crying → dehydration
Describe Inspection of Abdominal Size/Shape
Protuberant (bulging outward) abdomen → ascites, fluid retention, gaseous distention, tumor
Depressed/concave abdomen → high abdominal obstruction, dehydration
Describe Inspection of Mental Status
Changes can occur w/ severe dehydration, anaphylactic rxn, and inc ammonia levels
Lethargy occurs more rapidly in children
Describe Auscultation of GI in Children
Hyperactive BS → diarrhea, gastroenteritis
Hypoactive or absent → obstructive process → REPORT
Describe Palpation for GI in Children
Palpable kidneys (except neonates) → tumors, hydronephrosis
Areas of firmness/masses → tumor, stool in abdomen
Tender = Abnormal
Right Upper tenderness → liver enlargement
Right Lower pain → rebound tenderness (pain upon release of pressure) → warning sign of appendicitis
Stool Collection Techniques
Diapers, Runny Stool, Older Ambulator Child, Bedridden Child
Describe Diapers (Stool Collection Method)
Tongue blade to scrape a specimen into the collection container
Not sterile procedure, stool isn’t sterile
Describe Runny Stool (Stool Collection Method)
piece of plastic wrap in the diaper
very liquid stool - requires urine bag to the anal area
Describe Older Ambulatory Stool Collection Method
1st → urinate in toilet
Retrieve specimen from a clean collection container fitting under the seat at the back of the toilet
Describe Bedridden Child (Stool Collection Method)
Collect specimen from a clean bedpan
Don’t allow urine to contaminate the stool specimen
What are Stool Diversions?
surgical procedures of bringing portion of small or large
intestine to surface of abdomen creating an ostomy
Describe Ostomy Care
Materials: warm washcloths, skin barrier powder/paste, and/or sealant (protects skin), pencil/pen, scissors, pattern to measure stoma size
Take off Pouch → Observe stoma and skin
Stoma should be moist and pink or red → proper circulation to intestine
Notify MD if volume of stool increases or if stoma is prolapses or retracted
Measure stoma, mark new pouch, and cut the backing → apply new pouch → need to be changed q 1-4 days
Describe Ostomy education
Avoid tight clothing around site
Store supplies in cool/dry place
Inform Schools
Upper GI Series (Barium Swallow)
Visualizes form, position, mucosal folds, peristaltic activity & motility of esophagus, stomach, upper GI tract
X-rays after drinking barium contrast
When do you use a Barium Swallow?
Foreign body ingestion,abdominal pain, dysphagia, malrotation
Barium Enema
A barium enema is a special type of X-ray that takes images of the large intestine (colon, rectum and anus).
It uses a contrast substance to coat the large intestine
Gastric emptying study
A medical test that measures how long it takes for food or drink to move through the stomach and empty from it.
It is used to assess gastric motility
Abdominal Ultrasound
An abdominal ultrasound is a medical imaging test that uses sound waves to see inside the belly area, also called the abdomen
CT Scan
With or Without Contrast
MRI
Generates a strong magnetic field, radio waves, and a computer algorithm to create detailed images without any radiation
When do you use an Abdominal Ultrasound?
Abdominal pain, V, pregnancy, abnormal
liver tests, masses, enlarged organs
Do not use barium, decreases visualization of organs
Flat Plate of Abdomen
Radiograph of patient lying flat, examines the abdomen
Gastroscopy (EGD)
visualization & biopsies of upper GI tract w/ fiberoptic instrument
When do you need a EGD?
dysphagia, foreign body removal, epigastric/abdominal pain, celiac disease
Colonoscopy
Lower endoscopy
visualization & biopsies of lower GI tract w/ fiberoptic instrument
Common Medical Treatments
Hydration (oral, enteral, and IV)
Providing adequate nutrition (oral, enteral, and IV)
Enemas and bowel preparations
Ostomies—surgical opening into a digestive organ
Probiotics—support/replace intestinal microbial flora
Medications
Describe Cleansing Enema
Insert of Fluid into rectum to soften stool and stimulate bowel movement
Used for fecal impaction or severe constipation
Describe Bowel Prep
Highly osmotic fluids to induce severe diarrhea to clean the entire bowel
Prep for colonoscopy or Bowel Surgery
Different Types of Feeding Tubes
Orogastric (OG)
Nasogastric (NG)
Gastrostomy
Jejunostomy
Oral Rehydration Therapy
Fluids containing electrolytes and glucose to prevent dehydration/promote rehydration
75 mmol/L Sodium Chloride
13.5g/L Glucose
Pedialyte, Infalyte, Ricelyte
Mild/Mod Rehydr: requires 50 to 100 mL/kg of ORS over 4 hours
NOT for rehydration: tap water, milk, undiluted fruit juice, soup, broth
Probiotics
Food supplement containing dormant bacteria, when activated = alter intestinal microflora
Total Parental Nutrition
TPN - Intravenous Complete Nutrition, provides glucose, protein, lipids, vitamins, and minerals
List of Medications
Histamine-2 blockers (proton pump inhibitors)
Prokinetics
Antibacterial/antibiotics
Corticosteroids, immunosuppressants
Stimulants, laxatives
Antidiarrheals and antiemetics
Anticholinergics
Anti-inflammatories
Describe Histamine-2 blockers
Proton pump inhibitors
decrease in histamine production → reducing gastric acid secretion, used for heartburn, esophagitis, GERD, benign duodenal/gastric ulcers
NI: causes drowsiness/dizziness
Describe Prokinetics
They stimulate muscle contractions in the stomach and intestines to:
Speed up gastric emptying
Reduce reflux by tightening the lower esophageal sphincter (LES)
For erosive esophagitis, symptomatic GERD, H. Pylori eradication
headache, nausea, abdominal pain, diarrhea
Describe Corticosteroids
Act systemically to reduce inflammation and suppress normal immune response
Used for inflammatory bowel disease, autoimmune disorders
Systemic Adverse Effects: hirsutism, osteoporosis, GI Upset, cushingoid appearance, intraocular pressure, personality changes
Describe Immunosuppressants
Suppress immune system to keep autoimmune disorders in remission (Crohns, Ulcerative Colitis, Autoimmune Hepatits)
Check levels to determine metabolite levels
Potential hepatotoxicity
Describe Stimulants
Stimulates peristalsis in large intestine produces BM
Relieves constipation
Can cause cramping/diarrhea, assess stool patterns
Describe Laxatives
softens stool to allow easier passage through colon.
Relieves Constipation
Monitor stool patterns and doses (adjust for child)
Describe Antidiarrheals
Decreases peristalsis prolonging passing of stool through intestine.
Treats diarrhea related to short bowel syndrome, chronic nonspecific diarrhea, IBS (irritable bowel syndrome)
May cause drowsiness or constipation
Describe Antiemetics
Acts on CNS transmitters to prevent nausea and vomitting
CNS effects; drowsiness or irritability
Describe Anticholinergics
Controls abdominal spasms and cramping associated with IBS, functional bowel disorders
May cause excessive thirst, dizziness
Encourage plenty of fluid intake
Describe Anti-Inflammatory
Reduces inflammation in the colon associative w/ ulcerative colitis, proctitis.
monitor stool output for presence of oral medication as it indicated poor absorption
Risk Factors for GI Disorders
Prematurity
Family Hx
Genetic Sx
Chronic Illness
Prenatal factors
Exposure to infectious agents
Foreign Travel
Immune Deficiency, Chronic Steroid use
Risk Factors for Dehydration
Diarrhea
Vomiting
Decreased Oral Intake
Sustained High Fever
Diabetic Ketoacidosis
Extensive burns
Acute GI disorders
Dehydration, vomiting, diarrhea
Oral candidiasis and oral lesions
Appendicitis
Intussusception, malrotation, and volvulus
Hypertrophic pyloric stenosis
What is Malrotation?
Birth defect that occurs when the intestines do not correctly or completely rotate into their normal final position during development.
What is Volvulus?
condition where part of the intestine twists around and folds over itself, leading to bowel obstruction
Structural Anomalies of GI Tract
Cleft Lip & Palate
Meckel Diverticulum
Hernias (inguinal & umbilical)
Chronic GI Disorders
GER, GERD
Peptic Ulcer disease
constipation/encopresis (functional fecal incontinence or soiling)
Hirschsprung Disease
Short Bowel Syndrome
Celiac disease
Inflammatory bowel disease (Chron’s, Colitis)
Failure to Thrive
Hepatobiliary Disorders
Pancreatitis
Gallbladder disease
Biliary Atresia
Hepatitis (multiple types)
Cirrhosis and portal hypertension
Liver transplantation
When does the Suck and Swallow reflex develop?
34 weeks
When do coordinated oral pharyngeal movements (to swallow solids) develop?
2 months
When is Stool frequency highest?
Infancy
When do we gain control of stool?
Achieved by 18 months to 4 years
Describe Preschooler GI Development Changes
Continues having appetite fluctuations, with periods of overeating or refusal to eat
Weight gain 4-5 lbs/year
Describe Toddler GI Development Changes
Weight gain 5-6lbs/year
Growth of digestive system slows during toddler, leading to reduction in caloric needs
Avg toddler needs 102/kcal/kg (46kcal/lb)
Functional Gastrointestinal Disorders
GERD
Vomiting
Diarrhea
Constipation
Irritable Bowel Syndrome (IBS)
Obstructive Disorders
Hypertrophic pyloric stenosis
Intussusception
Volvulus
Hirschsprung's disease
Describe Diarrhea
Acute or Chronic excessive loss of fluid and electrolytes in the stool
Acute = caused by viruses
Chronic = longer than 2 wks
Risk Factors for Chronic Diarrhea
Ingestion of undercooked meats, foreign travel, day care attendance, well water use
Diarrhea Assessment
Moderate - Severe: decrease tear production, sunken orbits, dry mucous membranes, lethargy, tenting
Anal area = redness and rash
Diarrhea Management
Restore F/E balance
Oral Rehydration therapy
Acute diarrhea (infect) → hand hygiene, preventative measures
Chronic → Fluid Intake
Can be result from excessive intake of formula, water, fruit juice
avoid fluids high glucose → worsens
Describe GER
Gastroesophageal Reflux
Return of gastric contents from the stomach through the lower esophageal sphincter into the esophagus
Benign, occurs during 1st year of life, resolves 12-18months
Common in premmies
Assessment: nonbilious vomiting and regurg
Describe GERD
Gastroesophageal Reflux Disease
Gastric contents back into the esophagus or oropharynx (Pathologic)
In Infants older than 6months, children with congenital or neurological problems (Physiologic)
Not relieved by simple measures
Complications: laryngitis, recurrent pneumonia, asthma, acute life-threatening events, apnea
Describe GERD Assessment
Regurg feedings with slow growth/poor weight gain
esophagitis - excessive crying
Apnea/Resp Problems
Anemia
Not all children vomit → irritability, posturing, grimacing w/ feedings
Diagnosis:
Upper GI
Barium Swallow
24hr Intra-esophageal pH monitoring study
Describe GERD Management
Promoting safe feeding techniques/positioning
Elevated HOB, upright 30 min after feeding
Avoid prone
Small frequent feeding
Burp
Medication:
Decr acid production, stabilize pH
Prokinetic agents - empties stomach quickly and minimizes gastric contents
Post OP Care
Nissen fundoplication
Gastrostomy tube
Describe Nissen Fundoplication
Creates one way valve by wrapping gastric fundus 360 degrees around lower end of esophagus
Severe cases may need G-Tube for 6-8 weeks after surgery
Describe Appendicitis
Inflammation or Infection of Appendix
Rare in children < 2 yrs
Begins as pain in periumbilical area
Progresses over 4-6 hrs in right lower area
S/S: low grade fever, nausea, anorexia
Sudden pain relief - rupture of appendix → peritonitis
Describe Perforation
hole that forms in a structure
Typically GI
Perforation of appendix → pain relieved → returns as peritonitis
Abdominal distention
High fever
Dehydrated
Interventions of Perforation
Extra Fluids
NG to decompress stomach
IV antibiotics prior to surgery
Fever and Pain Control
AMBULATE
Cough and Deep Breathe
Pain Management
Assessment Appendiciits
Symptoms develop over 12 hr period
Pain, anorexia, nausea/vomiting, fever simultaneously
Vomiting precedes pain, suspect Gastroenteritis
Pain precedes vomiting, appendicitis
Child may lie down in knee-chest position
Greatest pain in right lower
Describe Intussusception
proximal segment of bowel ‘telescopes’ (sucks into itself) into a more distal segment
Common cause of intest obstruct 3-25 months
Causes: edema, vascular compromise, and ultimately partial/total bowel obstruction
1-2 yr old
Risk Factors: cystic fibrosis, celiac disease, 24hrs to treat bowel becomes necrotic → septic → death
Diagnosed: Contrast Enema
Intussusception Assessment
Sx flare and regress
hallmark sign: sausage shaped mass in upper mid abdomen
Bleeding results in passage of blood and mucous in stool
Currrant Jelly Stool (late sign)
pain mimics colic
pulls legs up toward abdomen
bilious vomiting (late sign) → REPORT MD
Intussusception Management
1st choice - air enema
barium enema - reduces large percentages of intussusception cases
portion of bowel must be resected if interventions are unsuccessful
Describe Hirschsprung Disease
Obstruction from motility of intestinal tract
Due to lack of ganglion cells in intestine
Congential Megacolon
Risk Factors - Chromosomal abnormalities, family hx of hirsch, down syndrome
Hirschsprung Disease Diagnosis and Symptoms
Newborn
Failure to pass meconium with first 48hrs of life
Failure to thrive
Poor feeding
Chronic constipation, vomiting, abdominal obstruction
Diagnosis:
Xray, dilated loop of bowel
Barium enema
Biopsy
Hirschsprung Disease Management/Treatment
Promote proper bowel function
Surgical resection of aganglionic
bowel and reanastomosis of remaining intestine
Rectal Biopsy
Ostomy to divert stool through stoma → allows resected area to heal → closed later
Describe Cleft Lip
Most Common Congential Craniofacial anomaly
1 in every 700 births
30% have genetic syndromes
Heart defect, ear malform, skeletal deform, GU abnorm
Occurs early in Pregnancy
5-6 weeks gestation = lip tissue fuses
7-9 palate closes
Lip or Palate does not fuse → CLEFT
50% of infants with cleft lips have cleft palate
Buildup of fluid in middle ear → Otitis media
Cleft Lip Characteristics
Primary/Permanent teeth - missing, malformed, unusually positioned
Nasal quality to speech, delays in speech development
Unilateral (left side more common) or bilateral
Cleft Lip Management
Surgical repair
Lip: 2-3 months
Palate: 6-9 months
Prevent injury to suture line
Promote adequate nutrition
Encourage infant-parent bonding
Describe Failure to Thrive
Inadequate growth resulting from inability to obtain or use calories required for growth
Uses standards of infants and toddlers younger than 3 yrs
Organic (physical cause): heart defect, GER, renal insufficiency, malabsorption, endocrine disease, cystic fibrosis, AIDS
Non-Organic (no associ medical condition): Neglect, inadequate intake of calories, disturbed bonding