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What is mitosis?
cell division
What is mitosis for?
growth and repair of an individual
What is Meiosis?
Meiosis is a type of cell division that produces gametes
Mitosis turns _ cell into _ cells
1-->2
in Mitosis, name the original cells (before mitosis) and the resulting cells, are the identical?
Parent cell, daughter cells, genetically identical to each other
What does the cell cycle represent
the growth and division of cells
What is the phase during the growth of cells where cells do not divide, what occurs during this phase?
interphase, the growth and copying of DNA
Who do cells need to copy its DNA before dividing?
Because every daughter cell needs its own copy to grow and function
what is a Karyotype?
the number and visual appearance of the chromosomes in the cell nuclei of an organism or species.
What can you tell about an individual using a Karyotype?
abnormalities derived form chromosome abnormalities, sex of an individual
What does DNA stand for?
deoxyribonucleic acid
What three things are determined by the genetic info in DNA?
How an organism develops, how each cell reacts to each other, what structures will form
What are the building blocks of life?
Amino Acids
recite the flow chart of how an organism is made up (small to large)
Amino acids construct proteins which make up cells to form tissue which is a part of organs which make up organisms
Describe the structure of DNA
double helix, like a twisted ladder with each rung being a base pair
What four common chemicals can be found in every organisms gene
adenine (A) , thymine (T) guanine (G) and cytosine (C)
What base pairs are formed within DNA
adenine (A) and thymine (T) join together - A-T
guanine (G) and cytosine (C) join together - G-C
What is a gene?
A specific segment of DNA with a unique combination of base pairs that construct a unique protein
Can genes be passed on from one generation to the next?
Yes.
Allele
different versions of the same gene, e.g eye colour
Allosomes and what possible pairs?
sex chromosomes (1 pair-XX and XY)
Chromosomes
tightly coiled strands of DNA
Autosomes
non-sex chromosomes 22xpairs
Trisomy
3 chromosomes in a pair
monosomy
a single chromosome in a pair
Flow chart for the production of cells, describe what happens
DNA makes partial genetic code with one side-->RNA travels outside nucleus to ribosome-->Ribosome reads codons to produce specific amino acids-->protein-->form cell
What is a Codon?
a three base sequence on RNA that codes for an amino acid
What is the formula to calculate all possible permutations?
P(permutations)=L(number of objects)^S(how many in each group)
How to determine sequences are code for the same protein?
If the sequence shares the same letter representation of amino acids as another
What is the structure of DNA, NOT DOUBLE HELIX
-composed of polynucleotides -- have a phosphate group, deoxyribose sugar and a nitrogen containing bases (adenine, thymine, cytosine and guanine)
What is RNA
ribonucleic acid with a single strand helix structure
difference between DNA and RNA
single vs double helix structure
uracil vs thymine
RNA able to leave nucleus
Why does Adenine go to thymine and cytosine go to guanine and vice versa?
their structure and shapes most easily fit together
describe the process of transcription
RNA polymerase 'unzips' DNA (of a gene) to let rRNA to be coded, codes the opposite of the nucleic acid along the gene.
Describe the process of translation
mRNA travels out of nucleus to ribosome, codons clings to specific tRNA (which clings with amino acid) to produce amino acid by coding the opposite on mRNA (back to original) which produces amino acids to eventually form a protein
What are somatic cells?
your body cells- the cells that make up your tissue and organs
functions of proteins (acronym)
SHITSME, structure, hormones, immunity, transport, sensory, movement, enzymes
what are mutations?
any change in the genetic sequence of an organism, a nucleotide can be swapped, deleted or added
Gene mutations can be…
Spontaneous - (error-natural), internal
Induced - exposure to mutagens
what are mutagens and examples:
physicial or chemical agents that cause mutations through altering DNA, Radiation (UV), Chemicals (Nitrate), infectious agents (HPV)
How many chromosomes are in a sex cell?
23 chromosomes
homologuous chromosomes have… is one each obtained by one parent?
two chromosomes containing copies of the same genes in the same locations, parents give one in a pair
homozygous
Two of the same alleles for a trait (blue + blue)
Heterozygous
An organism that has two different alleles for a trait (blue + brown)
Phenotype
An organism's physical appearance, or visible traits.
dominant allele
An allele whose trait always shows up in the organism when the allele is present.
recessive allele
An allele that is masked when a dominant allele is present
The inheritance of a recessive trait occurs only when
each parent contributes one allele for the trait
You have a __% chance to pass on either recessive or dominant (heterozygous)
50%
How to construct Punnett squares
each parent allele genotype on both axis, 4 squares, each square has equal chance
Males can't be carriers of sex-linked disorders because…
they only have one x chromosome
alleles are assigned to which chromosome in sex-linked inheritance?
the x chromosome
for non sex-linked inheritance, each parent has a __ possibility for handing a recessive gene when: both parents are carriers, when one parent is, when none are
50%, 50%, 0%
What is used to display genetic patterns in a tree
a pedigree is used
What symbols in a pedigree are males, and females, affected and unaffected
males are square, females are spheres, affected=coloured in, non-affected=not coloured in
what is point mutation?
a change in a single base pair in DNA
What is insertion mutation?
the addition of a base, causing shift in framework
What is deletion mutation?
the removal of a base, causing a shift in framework
How to determine how many chromosomes in a somatic and gamete
number of chromosomes on a karyotype=23=amount of chromosomes in a gamete= to the amount of PAIRS of chromosomes in a somatic cell